Table S1 Affymetrix expression profiling in resting B cells upregulated in Suv4-20h dn Affy Id p-Value log(fc) Gene Symbol Gene Name 1436148_at 0,000 4,06 1449314_at 0,001 3,67 Zfpm2 zinc finger protein, multitype 2 1430174_at 0,001 3,43 A930010G16Rik RIKEN cDNA A930010G16 gene 1459452_at 0,002 3,41 Cml2 camello-like 2 1437299_at 0,002 3,40 1455977_x_at 0,007 3,03 1435933_at 0,006 3,03 Scn2a1 sodium channel, voltage-gated, type II, alpha 1 1439712_at 0,007 2,76 Ints10 integrator complex subunit 10 1418359_at 0,010 2,74 Wbscr27 Williams Beuren syndrome chromosome region 27 (human) 1438392_at 0,001 2,74 Cd247 CD247 antigen 1426470_at 0,004 2,72 Tbp TATA box binding protein 1450387_s_at 0,008 2,70 Ak3l1 adenylate kinase 3 alpha-like 1 1457235_at 0,002 2,66 Ran RAN, member RAS oncogene family 1437060_at 0,003 2,65 Olfm4 olfactomedin 4 1441515_at 0,001 2,58 1443648_at 0,004 2,54 9530003O04Rik RIKEN cDNA 9530003O04 gene 1435281_at 0,001 2,53 Cpt1c carnitine palmitoyltransferase 1c 1434098_at 0,007 2,51 Glra2 glycine receptor, alpha 2 subunit 1431977_at 0,010 2,49 4933402J15Rik RIKEN cDNA 4933402J15 gene 1443501_at 0,002 2,48 hypothetical protein LOC667787 1438237_at 0,006 2,45 Rex2 reduced expression 2 1427681_s_at 0,003 2,45 V2r3 vomeronasal 2, receptor, 3 1456839_at 0,002 2,44 AL022681 expressed sequence AL022681 1452827_at 0,003 2,43 1500009C09Rik RIKEN cDNA 1500009C09 gene 1428321_at 0,001 2,42 Eml1 echinoderm microtubule associated protein like 1 1456401_at 0,008 2,40 Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 1456925_at 0,005 2,35 P2rxl1 purinergic receptor P2X-like 1, orphan receptor 1449457_at 0,010 2,35 Acot12 acyl-CoA thioesterase 12 1459260_at 0,008 2,35 1420362_a_at 0,001 2,31 Bik Bcl2-interacting killer 1453592_at 0,001 2,28 2010005E21Rik RIKEN cDNA 2010005E21 gene 1436799_at 0,008 2,27 D230005D02Rik RIKEN cDNA D230005D02 gene 1420536_at 0,000 2,27 Crybb2 crystallin, beta B2 1445070_at 0,010 2,25 1456345_at 0,002 2,23 1425679_a_at 0,000 2,22 Mapk8ip1 mitogen activated protein kinase 8 interacting protein 1 1460252_s_at 0,005 2,19 Zfp105 zinc finger protein 105 1439717_at 0,001 2,18 B230362M20Rik RIKEN cDNA B230362M20 gene 1419127_at 0,004 2,18 Npy neuropeptide Y 1454487_at 0,000 2,17 5830490A04Rik RIKEN cDNA 5830490A04 gene 1423865_at 0,008 2,15 Slc44a1 solute carrier family 44, member 1 1455463_at 0,003 2,14 Phyhip phytanoyl-CoA hydroxylase interacting protein 1429523_a_at 0,005 2,14 Slc39a5 solute carrier family 39 (metal ion transporter), member 5 1450228_a_at 0,010 2,14 Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma 1445275_at 0,010 2,13 C130092O11Rik RIKEN cDNA C130092O11 gene 1422835_at 0,005 2,10 AW555701 expressed sequence AW555701 1451279_at 0,004 2,07 5033405M01Rik RIKEN cDNA 5033405M01 gene 1445797_at 0,008 2,07 Pam peptidylglycine alpha-amidating monooxygenase 1428238_at 0,005 2,06 2700059D21Rik RIKEN cDNA 2700059D21 gene 1446561_at 0,010 2,05 Pax8 paired box gene 8 1424652_at 0,001 2,05 Tmem166 transmembrane protein 166 1436806_at 0,010 2,04 Trim62 tripartite motif-containing 62 1438486_at 0,006 2,03 Tssk4 testis-specific serine kinase 4 1452872_at 0,006 2,03 Page 1 1450481_at 0,010 2,00 Mybl1 myeloblastosis oncogene-like 1 1450097_s_at 0,010 1,99 Gna12 guanine nucleotide binding protein, alpha 12 1440589_at 0,007 1,96 1416193_at 0,001 1,94 Car1 carbonic anhydrase 1 1445289_at 0,008 1,94 1453930_at 0,007 1,88 1110015M06Rik RIKEN cDNA 1110015M06 gene 1445669_at 0,008 1,80 Spry4 sprouty homolog 4 (Drosophila) 1455970_at 0,005 1,80 1458674_at 0,003 1,79 Ptger1 prostaglandin E receptor 1 (subtype EP1) 1426959_at 0,010 1,76 Bdh1 3-hydroxybutyrate dehydrogenase, type 1 1440661_at 0,003 1,73 A430010J10Rik RIKEN cDNA A430010J10 gene 1443633_at 0,005 1,71 1700086O06Rik RIKEN cDNA 1700086O06 gene 1431459_at 0,009 1,69 9430013L14Rik RIKEN cDNA 9430013L14 gene 1425528_at 0,005 1,66 Prrx1 paired related homeobox 1 1441670_at 0,007 1,66 Tiam2 T-cell lymphoma invasion and metastasis 2 1420561_at 0,008 1,65 Trpc7 transient receptor potential cation channel, subfamily C, member 7 downregulated in Suv4-20h dn Affy Id p-Value log(fc) Gene Symbol Gene Name 1438881_at 0,008 -4,04 Vezt vezatin, adherens junctions transmembrane protein 1460107_at 0,004 -3,80 1700129I04Rik RIKEN cDNA 1700129I04 gene 1452532_x_at 0,010 -3,67 Ceacam1 CEA-related cell adhesion molecule 1 1458917_at 0,007 -3,44 Depdc5 DEP domain containing 5 1442938_at 0,008 -3,35 1443402_at 0,001 -3,32 Phka2 phosphorylase kinase alpha 2 1416081_at 0,004 -3,27 Smad1 MAD homolog 1 (Drosophila) 1432716_at 0,007 -3,19 Lrrn1 leucine rich repeat protein 1, neuronal 1444575_at 0,005 -2,86 1500002O20Rik RIKEN cDNA 1500002O20 gene 1447723_at 0,004 -2,63 AFFX-ThrX-5_at 0,006 -2,57 1453843_at 0,003 -2,36 Thap6 THAP domain containing 6 1444416_at 0,005 -2,32 Cenpa centromere protein A 1425236_at 0,003 -2,28 Col20a1 collagen, type XX, alpha 1 1439801_at 0,002 -2,28 Sunc1 Sad1 and UNC84 domain containing 1 1431702_at 0,010 -2,27 1458383_at 0,008 -2,20 1444147_at 0,007 -2,19 1447626_x_at 0,007 -2,17 Arid3b AT rich interactive domain 3B (Bright like) 1425290_at 0,004 -2,06 Stx19 syntaxin 19 1416077_at 0,008 -2,04 Adm adrenomedullin 1446576_at 0,004 -2,03 4931419K03Rik RIKEN cDNA 4931419K03 gene 1440410_at 0,003 -1,99 A930011G23Rik RIKEN cDNA A930011G23 gene 1421403_at 0,002 -1,89 Pi15 peptidase inhibitor 15 1425592_at 0,006 -1,81 Tnpo2 transportin 2 (importin 3, karyopherin beta 2b) 1425999_at 0,007 -1,80 complement factor H related protein 3A4/5G4 1426715_s_at 0,009 -1,80 D11Ertd18e DNA segment, Chr 11, ERATO Doi 18, expressed 1452022_at 0,007 -1,77 Baalc brain and acute leukemia, cytoplasmic 1421803_at 0,004 -1,72 Apbh androgen-binding protein eta 1425538_x_at 0,009 -1,71 Ceacam1 CEA-related cell adhesion molecule 1 Page 2.