a YEAR of STORIES 2013 Annual Report 4 MEssAGE from the PRESIDENT and CHAIRMAN of the BOARD 6 COLLABORATIONS DRAW top RESEARCH LEADERS to MCLEAN 8 MASTERING anxiety DISORDERS a YEAR of STORIES 10 REACHING more PEOPLE by TRANSFORMING MCLEAN SOUTHEAST 12 PROMOTING WELLNEss for GIRLS and WOMEN 14 EDUCATING the NEXT GENERATION 16 MCLEAN LEADERS draw AccOLADES 18 ENDOWED CHAIR PROVIDES RESOURCES to DELIVER on MCLEAN’S MIssION 19 the MARY BELKNAP SOCIETY 20 WAys to GIVE 21 2013 FINANCIALS 22 MCLEAN LEADERSHIP 2 McLean Hospital 2013 Annual Report PAGE 14 PAGE 9 PAGE 12 PAGE 10 PAGE 6 PAGE 17 PAGE 11 PAGE 8 OUR MISSION McLean Hospital is dedicated to improving the lives of people and families affected by psychiatric illness. McLean pursues this mission by: Providing the highest quality compassionate, specialized and effective clinical care, in partnership with those whom we serve; Conducting state-of-the-art scientific investigation to maximize discovery and accelerate translation of findings towards achieving prevention and cures; Training the next generation of leaders in psychiatry, mental health and neuroscience; Providing public education to facilitate enlightened policy and eliminate stigma. STORIES of COmpAssION, INNOVATION and DEDICATION From left: Scott L. Rauch, MD, president and psychiatrist in chief, and David S. Barlow, chairman of the board 4 McLean Hospital 2013 Annual Report Dear Friends, Each of us has a story about who we are, the women, Shelly F. Greenfield, MD, MPH, and experiences that helped shape us and what moved the clinicians within the Division of Women’s us to be a part of the McLean community. Some Mental Health are promoting wellness for of us have witnessed firsthand the pain, fear and girls and women throughout the life span. uncertainty experienced by a loved one with n As the newly named directors of the psychiatric illness. Others have seen how stigma Massachusetts General Hospital (MGH)/ can be a caustic deterrent from preventing people McLean Hospital Adult Psychiatry Residency from seeking psychiatric care. Each of us has been Program and the MGH/McLean Child and motivated by different circumstances, but despite Adolescent Psychiatry Residency Program, the varied paths that led us to McLean, there is Felicia Smith, MD, and David Rubin, MD, are one common denominator—our collective drive to dedicated to providing unparalleled training and accomplish McLean’s mission of improving the lives guidance to tomorrow’s psychiatric leaders. of people with psychiatric illness and their families. n The McLean Anxiety Mastery Program is In 2013, we made great strides in fulfilling that one of only a handful of programs in the mission—growing clinical programs, strengthening country to provide intensive and evidence- research, and increasing educational outreach to based treatment for youths suffering professionals, patients and families. As a team we from debilitating anxiety disorders. have made meaningful progress, and through our n expansion of services and our work in the community, United States President Barack Obama recently we continue to respond to the needs of patients and called for a national dialogue about mental families across Massachusetts and around the globe. health. In support of the president’s charge, McLean Hospital launched its first social media In this 2013 Annual Report, aptly titled A Year of campaign with the goal of encouraging more public Stories, you will meet a sampling of our dedicated conversation about mental health and reducing team who make up the fabric of McLean. On the the stigma with which it is often associated. following pages, you will read their compelling stories, n including these: Rose-Marie and Eijk van Otterloo want to make a difference in the lives of people with n Despite coming from very different places psychiatric illness. Through their continued geographically, two of the world’s most support of McLean Hospital, including making esteemed neuroscientists—Vadim Bolshakov, a generous gift to establish the Rose-Marie and PhD, and Uwe Rudolph, Dr med—found Eijk van Otterloo Endowed Chair of Psychiatry opportunity half the world away in the at McLean Hospital, they are doing just that. very same place: McLean Hospital. As you read A Year of Stories, we hope that you will n Through treatment, research and education be inspired by the clinicians, researchers, educators, that appreciate the biological, sociocultural donors, faculty and staff who have committed their and environmental factors that are unique to lives to delivering on the mission of McLean Hospital. With warmest regards, Scott L. Rauch, MD David S. Barlow President and Psychiatrist in Chief Chairman of the Board McLean Hospital 2013 Annual Report 5 From left: Vadim Bolshakov, PhD, and Uwe Rudolph, Dr med COLLABORATIONS DRAW top RESEARCH LEADERS to MCLEAN Despite coming from very different places a national search for an assistant professor and geographically, two of the world’s most esteemed invited me to interview. The rest is history.” neuroscientists found opportunity half the world In 1997, Bolshakov made the move to McLean, away in the very same place: McLean Hospital. where he founded the Cellular Neurobiology As a graduate student at the Russian Academy of Laboratory, and today is considered one of the Sciences in St. Petersburg, Russia, Vadim Bolshakov, world’s foremost psychiatric neuroscientists. PhD, could not have predicted that his career “McLean has offered me many opportunities path would lead him out of his home country to to expand my research and to collaborate with America. In fact, before accepting a postdoctoral colleagues both within the hospital and globally,” position at Columbia University, Bolshakov said Bolshakov, whose influential work has had never even visited the United States. advanced the understanding of fear mechanisms “I was excited at the prospect of working at Columbia, in the brain and how they influence conditions where I could develop and possibly flourish under such as post-traumatic stress disorder and anxiety. the mentorship of Dr. Steven Siegelbaum,” said “Collaboration is an integral part of research Bolshakov. “After six years there, having published because it allows us to build off of one another’s several high-profile papers, I knew that I was ready strengths in order to produce results that have to take the next step. Fortunately, while I was great implications for the scientific community.” coming to this realization, McLean was performing 6 McLean Hospital 2013 Annual Report “We are working together in order to advance our Inspiring hope knowledge of the brain, and such advances may through research ultimately help to improve people’s lives,” said Uwe Rudolph, Dr med, director of the Laboratory As a trained certified public accountant (CPA), of Genetic Neuropharmacology at McLean. Raquel Espinosa followed a unique path to McLean, “Today, most successful research is teamwork. where she oversees the hospital’s Research My junior colleagues in the lab put in countless Administration Department. However, the detail- hours, doing all the experimental work and oriented work involved in becoming a CPA turns out making valuable intellectual contributions.” to have been a perfect training ground for Espinosa, who uses her love of numbers and details each day Like Bolshakov, Rudolph could have never to provide infrastructural support for the hospital’s predicted he would someday be one of McLean 66 laboratories and 388 research scientists and staff. Hospital’s leading investigators. His path to Although she lived in the United States for the Belmont started in Germany, where he completed first 10 years of her life, Espinosa spent the next both medical school and a research thesis in 17 years living in Uruguay, a small South American molecular pharmacology before receiving country located between Brazil and Argentina. postdoctoral research training at Houston’s After becoming a CPA, she moved back to America Baylor College of Medicine’s Department of Cell the week following graduation and quickly found Biology. It was at Baylor, under the mentorship her calling while working at Tufts Medical Center. of Lutz Birnbaumer, PhD, that he was first able to “From Tufts, I moved to Massachusetts General combine his medical background with his newly Hospital, where I was given opportunities to learn acquired skills in mouse molecular genetics. and grow. I was able to hone my skills and better His unique skills led him to the University of understand the needs of researchers and how to help Zürich in Switzerland, where he applied the them,” she said. “I discovered a passion for research techniques he learned at Baylor to neuroscience. and the hope that it inspires.” “In Zürich, I was fortunate to land in a highly Espinosa joined the McLean team in 2009 as a per collaborative environment with excellent diem employee and quickly became an invaluable institutional resources that enabled me to resource to the research community. In 2011, she was pursue an untested and thus high-risk approach promoted to director of Research Administration— to generate new knowledge relevant for future a position she takes great pride in holding. drug development,” explained Rudolph. “McLean has outstanding researchers and there Rudolph was recruited to McLean in 2005. His are so many opportunities to make a difference by pioneering and innovative research on the functions simplifying the administrative burden of specific neurotransmitter receptor subtypes on scientists,” said Espinosa.