Safety Data Sheet Revision Date 2021-02-08 Revision Number 4 1. Identification Product identifier Product Name ssDNA Binding Buffer Other means of identification Product Code ST0923 Synonyms No information available Recommended use of the chemical and restrictions on use Identified uses No information available Restrictions on use No information available Details of the supplier of the safety data sheet Supplier USA: Takara Bio USA, Inc. 1290 Terra Bella Avenue Mountain View, CA 94043 Phone: 800.662.2566/888.251.6618 Web: www.takarabio.com Emergency telephone number Emergency telephone In case of emergency, call PERS (Professional Emergency Resource Services) 1-800-633-8253 (US) or 801-629-0667 (international). 2. Hazard(s) identification Classification Acute toxicity - Oral Category 4 Acute toxicity - Dermal Category 4 Acute toxicity - Inhalation (Dusts/Mists) Category 4 Carcinogenicity Category 1B Hazards not otherwise classified (HNOC) Not applicable Label elements Danger Hazard statements Harmful if swallowed Harmful in contact with skin Harmful if inhaled _____________________________________________________________________________________________ Page 1 / 9 ST0923 - ssDNA Binding Buffer Revision Date 2021-02-08 _____________________________________________________________________________________________ May cause cancer Appearance Clear, colorless Physical state Liquid Odor Odorless Precautionary Statements - Prevention Obtain special instructions before use Do not handle until all safety precautions have been read and understood Wear protective gloves/protective clothing/eye protection/face protection Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Avoid breathing dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area Precautionary Statements - Response IF exposed or concerned: Get medical advice/attention Specific treatment (see .? on this label) IF ON SKIN: Wash with plenty of water and soap Call a POISON CENTER or doctor if you feel unwell Take off contaminated clothing and wash it before reuse IF INHALED: Remove person to fresh air and keep comfortable for breathing IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell Rinse mouth Precautionary Statements - Storage Store locked up Precautionary Statements - Disposal Dispose of contents/container to an approved waste disposal plant Unknown acute toxicity 0 % of the mixture consists of ingredient(s) of unknown acute oral toxicity 0 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist) Other information Harmful to aquatic life with long lasting effects. 3. Composition/information on ingredients Substance Not applicable. Mixture Chemical name CAS No Weight-% Trade secret Potassium thiocyanate 333-20-0 60 - 100 * 4. First-aid measures Description of first aid measures _____________________________________________________________________________________________ Page 2 / 9 ST0923 - ssDNA Binding Buffer Revision Date 2021-02-08 _____________________________________________________________________________________________ General advice IF exposed or concerned: Get medical advice/attention. Show this safety data sheet to the doctor in attendance. Inhalation Remove to fresh air. If symptoms persist, call a physician. If breathing has stopped, give artificial respiration. Get medical attention immediately. Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Consult a physician. Skin contact Wash off immediately with plenty of water for at least 15 minutes. If symptoms persist, call a physician. Ingestion Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Get medical attention. Self-protection of the first aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. Avoid breathing vapors or mists. Use personal protective equipment as required. See section 8 for more information. Most important symptoms and effects, both acute and delayed Symptoms Coughing and/ or wheezing. Difficulty in breathing. Indication of any immediate medical attention and special treatment needed Note to physicians Treat symptomatically. 5. Fire-fighting measures Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Large Fire CAUTION: Use of water spray when fighting fire may be inefficient. Unsuitable extinguishing media Do not scatter spilled material with high pressure water streams. Specific hazards arising from the No information available. chemical Explosion Data Sensitivity to mechanical impact None. Sensitivity to static discharge None. Special protective equipment for Firefighters should wear self-contained breathing apparatus and full firefighting turnout fire-fighters gear. Use personal protection equipment. 6. Accidental release measures Personal precautions, protective equipment and emergency procedures Personal precautions Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Avoid breathing vapors or mists. Use personal protective equipment as required. Other information Refer to protective measures listed in Sections 7 and 8. Methods and material for containment and cleaning up Methods for containment Prevent further leakage or spillage if safe to do so. Methods for cleaning up Pick up and transfer to properly labeled containers. _____________________________________________________________________________________________ Page 3 / 9 ST0923 - ssDNA Binding Buffer Revision Date 2021-02-08 _____________________________________________________________________________________________ 7. Handling and storage Precautions for safe handling Advice on safe handling Avoid contact with skin, eyes or clothing. Handle in accordance with good industrial hygiene and safety practice. Avoid breathing vapors or mists. Ensure adequate ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Do not eat, drink or smoke when using this product. Conditions for safe storage, including any incompatibilities Storage Conditions Store locked up. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep out of the reach of children. 8. Exposure controls/personal protection Control parameters Exposure Limits Chemical name ACGIH TLV OSHA PEL NIOSH Potassium thiocyanate - TWA: 5 mg/m3 IDLH: 25 mg/m3 333-20-0 (vacated) TWA: 5 mg/m3 S* Appropriate engineering controls Engineering controls Showers Eyewash stations Ventilation systems. Individual protection measures, such as personal protective equipment Eye/face protection Wear safety glasses with side shields (or goggles). Hand protection Wear suitable gloves. Skin and body protection Long sleeved clothing. Wear suitable protective clothing. Respiratory protection No protective equipment is needed under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required. General hygiene considerations Avoid contact with skin, eyes or clothing. Wear suitable gloves and eye/face protection. Wash hands before breaks and immediately after handling the product. Do not eat, drink or smoke when using this product. 9. Physical and chemical properties Information on basic physical and chemical properties Physical state Liquid Appearance Clear, colorless Color Clear Odor Odorless Odor Threshold No information available _____________________________________________________________________________________________ Page 4 / 9 ST0923 - ssDNA Binding Buffer Revision Date 2021-02-08 _____________________________________________________________________________________________ Property Values Remarks • Method pH <7 None known Melting point / freezing point No data available None known Boiling point/boiling range (°C) No data available None known Flash point No data available Open cup Evaporation Rate no data available None known Flammability (solid, gas) no data available None known Flammability Limit in Air None known Upper flammability limit: No data available Lower flammability limit: No data available Vapor pressure no data available None known Vapor density No data available None known Relative density None known Water solubility No data available None known Solubility in other solvents no data available None known Partition coefficient no data available None known Autoignition temperature No data available None known Decomposition temperature None known Kinematic viscosity No data available None known Dynamic Viscosity no data available None known Other information Explosive properties No information available Oxidizing properties No information available Softening point No information available Molecular Weight No information available VOC Content (%) No information available Liquid Density No information available Bulk Density No information available 10. Stability and reactivity Reactivity No information available. Chemical stability Stable under normal conditions. Possibility of hazardous reactions None under normal processing. Conditions to Avoid Excessive heat. Incompatible materials None known based on information supplied. Hazardous decomposition products None known based on information supplied. 11. Toxicological information