Defeating dementia: the road to 2025 worlddementiacouncil.org 1 ContentsWorld Dementia Council Introduction 3 Contributors 4 The Rt Hon David Cameron, former UK Prime Minister 4 Shinzo Abe, Prime Minister of Japan 5 Angel Gurría, Secretary-General, OECD 6 Tedros Adhanom Ghebreyesus, Director-General, WHO 7 Marty Reiswig, Person affected by dementia living in the United States 8 Nishi Pulugurtha, Caregiver living in India 9 Dennis Gillings, Former World Dementia Envoy and Founding Chairman, WDC 10 Acknowledgements and terminology 11 Chapter 1: A disease-modifying therapy 12 Funding 13 Data sharing 14 Recruitment for clinical trials 15 Chapter 2: Living well 18 National dementia plans 20 Diagnostic rates and prevalence 21 Support in the community 22 Chapter 3: Better care 24 Quality care 25 Collecting data 26 Technology 27 Chapter 4: Reducing the impact of dementia 28 Global brain health 29 Economic risk 31 Impact of dementia on women 31 Thematic conclusions 32 Bill Gates on innovation and data 32 Gabriela Michetti on low and middle-income countries 33 Maria Shriver on the global impact on women 34 G8 Declaration 11 December 2013 35 2 Defeating dementia: the road to 2025 Introduction Dementia is the 21st century’s biggest health challenge. These four areas are: Today almost 50 million people around the world have the • the search for a disease modifying therapy; disease and that number is set to triple by 2050. • the challenge of living well; In 2013, the then Prime Minister David Cameron used the • the need for better care; United Kingdom’s presidency of the G8 to host a historic • reducing the impact of dementia. summit in London which focused the international community’s attention on the growing dementia challenge. It is not to say that there are issues that lie outside these There, the G8 agreed key commitments, set out in their DUHDVWKDWDUHQRWVLJQLˋFDQW6LQFHWKHGHPHQWLD declaration and communique, on how global action could movement has grown and grown. From grassroots activism turn the tide on dementia by 2025. to advocacy at the United Nations, individuals and organisations are pushing for change. This report shines Five years on there is much to be proud of. The London a spotlight on a small number of areas where greater summit has helped propel forward international efforts international collaboration can help drive this. WRˋQGGLVHDVHPRGLI\LQJWKHUDSLHVLPSURYHFDUHUDLVH awareness and understand how we can reduce the risk In addition to these chapters, this report hears from of dementia. Progress has been made but the challenge LQGLYLGXDOVDQGRUJDQLVDWLRQVZKRˋYH\HDUVDJRDQGVLQFH remains immense. have done so much to help the cause. From understanding the basic biology of dementia, through Alongside these voices we hear the words of the most to tackling the still too prevalent perception that it is a important people of all – those affected by dementia. They natural part of ageing, there is no part of this agenda where DUHWKHUHDVRQZHDUHˋJKWLQJIRUWKLVFDXVH the job is done. It is vast. And no single report can cover the successes since 2013 nor the challenges of realising the The 2013 summit marked a turning point in the 2025 ambitions. international effort to meet the dementia challenge. The job is not done. The job is far from done. But we can No individual, no organisation and no country can FROOHFWLYHO\ORRNEDFNDWWKHODVWˋYH\HDUVDQGEHSURXG defeat dementia alone. The G8 summit aimed to of the advances that have been made since the G8 met in harness the strength of international collaboration to London. And with that sense of pride redouble our efforts improve the lives of people with the disease. In this to deliver on the 2025 goals. report we set out four areas where greater international cooperation through the G7 and G20, along with organisations like the European Union, Organisation for Economic Co-ordination and Development (OECD) and World Health Organization (WHO). Harry Johns Lenny Shallcross Chair, WDC Executive Director, WDC President and CEO, Alzheimer’s Association 3 World Dementia Council David Cameron Five years ago, I hosted the G8 summit in Lough This is the groundwork that will make breakthroughs Erne. As the leaders of the world arrived in Northern possible. But there is much further to go. Ireland, I had an urgent message for them. It was about dementia. I warned them that this health crisis had Funding is vital. In the UK, between 2012 and 2015, the world in its grip. That it was the only major cause of government funding for dementia research doubled death we couldn’t prevent or slow down or cure. to over £60 million a year. Yet dementia research still receives less funding than other major disease areas, $VSDUWRIWKH8.ȢV*SUHVLGHQF\ZHFRQYHQHGWKHˋUVW despite it being the biggest killer in our country. ever G8 dementia summit in London. Some ambitious goals were set for the international community to Technology is also key. It has the potential to transform meet by 2025, including the aim to identify a cure everything, from how we manage risk, to how we or a disease-modifying therapy for dementia. It was deliver care. Big data can rapidly accelerate dementia also here that we agreed the foundation of the research – not just biomedical research, but care World Dementia Council. research as well. The World Health Organization’s Global Dementia Observatory is a great way of pooling Why was it so important to bring world leaders information. We need more of that. together on this issue? Because this is a great global challenge of our time. 50 million people around the Five years ago, I was daunted when I explained the world have dementia; by 2050 that will have more scale of the challenge to those leaders. But now, than trebled to over 150 million. No individual, reading reports like this, I feel a deep sense of organisation or country is going to be able to solve it FRQˋGHQFH%HFDXVHWKHUHLVOLJKWDWWKHHQGRIDYHU\ alone. It doesn’t affect one country or some countries; long tunnel. We are going in the right direction. And if it affects us all. It is too big and too complex to tackle we keep up the pressure, take all the steps we’ve said without each other. And it will grow and grow if we we would, there’s no reason the diseases that cause don’t do more, and do so now. dementia cannot be defeated. As this report shows, we have made much progress WRZDUGVRXUJRDOVLQWKHODVWˋYH\HDUV First, on awareness. Countries across the world are raising awareness through programmes such as Dementia Friends. In fact, I made sure all my ministers took part in the programme – and now in the UK over two million people have followed suit. The Rt Hon David Cameron Second, on care. More people than ever are living in President, Alzheimer’s Research UK dementia-friendly communities and more people and Former Prime Minister of the are receiving good quality care. The world is a better United Kingdom, 2010–2016 SODFHIRUSHRSOHOLYLQJZLWKGHPHQWLDWKDQLWZDVˋYH years ago. Third, on risk. We are discovering more about how lifestyle and other factors can contribute towards a person’s risk of developing dementia. Fourth, on research. Across the world we are investing more in dementia research. In Britain, we established the UK Dementia Research Institute with government funding and additional funding from the charitable sector. There’s the Dementia Discovery Fund, which will help to turn research breakthroughs into potential new treatments. And I am proud to be President of Alzheimer’s Research UK, the charity which is backing new research and playing a leading role in the early diagnosis of dementia, with an overall ambition to detect the condition 10–15 years earlier than we do today. 4 Defeating dementia: the road to 2025 Shinzo Abe I would like to extend my heartfelt congratulations to To further advance research on dementia, in FY2016, WKH:RUOG'HPHQWLD&RXQFLO :'& XSRQ\RXUˋIWK it was suggested at the Japan Agency for Medical DQQLYHUVDU\DVZHOODVWKHSXEOLVKLQJRIWKLVˋYH\HDU Research and Development (AMED) that a system progress report. The WDC was established under the of international, multi-sectoral cooperation be United Kingdom’s leadership following the G8 London HVWDEOLVKHGIRUWKHHIIHFWLYHDQGHIˋFLHQWSURPRWLRQ 6XPPLWLQ,QWKHˋYH\HDUVVLQFHWKHQPDQ\ of dementia research. A research project was thus people around the world have come to the realization started on the construction of a concrete framework WKDWZHKDYHDVLJQLˋFDQWUHVSRQVLELOLW\WRDFWRQWKH WRWKDWHQG6LQFHWKLVˋVFDO\HDUGLVFXVVLRQKDVEHHQ issues of dementia. underway at expert meetings toward the creation RIDUHDOZRUOGWHVWˋHOGIRUQHZGHPHQWLDIULHQGO\ In addition to the adoption of the “G7 Ise-Shima products and services as part of this “Public-Private Vision for Global Health” at the 42nd G7 Summit Joint Demonstration Platform for Dementia (the G7 Ise-Shima Summit), which was held in Japan Patients” project. in 2016, the “Kobe Communiqué,” including global dementia initiatives based on Summit agreements, G20 meetings will be held in Japan in 2019, and we are was adopted at the G7 Health Ministers’ Meeting held considering the organization of discussions on themes in Kobe that same year. Japan will continue efforts related to the aging of society. Japan has achieved to maintain a leading role within the international the longest healthy life expectancy in the world, and FRPPXQLW\LQWKHˋJKWDJDLQVWGHPHQWLD it is expected that our healthy life expectancy will increase even further in the future. In preparation for With approximately 7 million elderly people projected the emergence of a “100-year life society,” Japan is to be living with dementia in Japan by 2025, in 2015, currently working to create society in which people of the Government established a “Comprehensive all ages can continue to meaningfully participate and Strategy to Accelerate Dementia Measures,” live healthy, active lives with peace of mind. It is my also known as the “New Orange Plan.” This plan hope that, as populations around the world continue promotes the creation of age- and dementia-friendly to age, we will be able to share Japan’s initiatives communities not only by the Ministry of Health, on aging far and wide, thereby contributing to the Labour and Welfare (MHLW), but also through resolution of international issues.