Supplementary table 3. Genes differentially expressed (log FC > 0.45 or logFC < ‐0.45) in response to stimuli at UVJ (control versus mated). “U” represents unique to the UVJ. A. UP‐REGULATED GENES SL Gene symbol or ID U Gene ID Panther Family/subfamily Functions (Panther Classification logFC System) 1 ENSGALG00000023898 U ENSGALG00000023898/F1NWQ8 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9 Cellular defense response, immune 1.68 (PTHR22826:SF107) response 2 PAPPA ENSGALG00000007079/F1N850 PAPPALYSIN‐1 (PTHR19325:SF347) Immune response, response to 1.45 external stimulus 3 ENSGALG00000012602 U ENSGALG00000012602/F1NYJ8 BPI FOLD‐CONTAINING FAMILY C PROTEIN (PTHR10504:SF17) Defense response to bacterium, 1.13 response to stress 4 ITGB4 U ENSGALG00000002389/E1C9G7 INTEGRIN BETA‐4 (PTHR10082:SF6) Response to external stimulus 0.72 5 MK06_CHICK U ENSGALG00000004690/Q5F3W3 MITOGEN‐ACTIVATED PROTEIN KINASE 6 (PTHR24055:SF171) Response to stress 0.60 6 RASA4 U ENSGALG00000001876/F1NF56 RAS GTPASE‐ACTIVATING PROTEIN 4‐RELATED (PTHR10194:SF4) 0.59 7 CREB1 U ENSGALG00000008494/E1BSK3 CYCLIC AMP‐RESPONSIVE ELEMENT‐BINDING PROTEIN 1 Response to stress 0.50 (PTHR22952:SF104) 8 SPDEF U ENSGALG00000002792/F1N9W6 SAM POINTED DOMAIN‐CONTAINING ETS TRANSCRIPTION FACTOR Cellular defense response 1.98 (PTHR11849:SF182) 9 EDIL3 ENSGALG00000015630/F1NCN3 EGF‐LIKE REPEAT AND DISCOIDIN I‐LIKE DOMAIN‐CONTAINING Response to external stimulus 1.81 PROTEIN 3 (PTHR10127:SF29) 10 SRPK1 U ENSGALG00000000890/E1C5I9 SRSF PROTEIN KINASE 1 (PTHR24055:SF101) Response to stress 1.43 11 SPATA13 U ENSGALG00000017116/F1P176 SPERMATOGENESIS‐ASSOCIATED PROTEIN 13 (PTHR22826:SF103) Cellular defense response, immune 1.28 response 12 GNA14 ENSGALG00000015176/F1NU41 GUANINE NUCLEOTIDE‐BINDING PROTEIN SUBUNIT ALPHA‐14 1.05 (PTHR10218:SF57) 13 ENSGALG00000003676 U ENSGALG00000003676/E1C2U5 JUNCTION PLAKOGLOBIN (PTHR23315:SF12) 0.86 14 WNT5B ENSGALG00000012998/F1NMK6 PROTEIN WNT‐5B (PTHR12027:SF87) 0.78 15 CD99L2 U ENSGALG00000009075/F1NGN9 CD99 ANTIGEN‐LIKE PROTEIN 2 (PTHR15076:SF13) Cellular defense response 0.71 16 TSPAN1 U ENSGALG00000010343/F1NBL2 TETRASPANIN‐1 (PTHR19282:SF153) Response to external stimulus 0.69 17 PP2AA_CHICK U ENSGALG00000010273/P48463 SERINE/THREONINE‐PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT Response to stress 0.62 BETA ISOFORM (PTHR11668:SF21) 18 C1QTNF3 ENSGALG00000003338/E1C6T7 COMPLEMENT C1Q TUMOR NECROSIS FACTOR‐RELATED PROTEIN 3 Immune response 2.60 (PTHR24022:SF76) 19 KALRN ENSGALG00000011744/F1NPK0 KALIRIN (PTHR22826:SF49) Cellular defense response, immune 1.59 response 20 IL5RA U ENSGALG00000008267/E1C261 INTERLEUKIN‐5 RECEPTOR SUBUNIT ALPHA (PTHR23036:SF17) Immune response 1.36 21 DNAJB5 ENSGALG00000001918/E1BWR7 DNAJ HOMOLOG SUBFAMILY B MEMBER 5 (PTHR24077:SF227) Response to stress 1.17 22 MAPK1 U ENSGALG00000001501/F1P066 MITOGEN‐ACTIVATED PROTEIN KINASE 1 (PTHR24055:SF161) Response to stress 1.11 23 PLEKHG1 U ENSGALG00000012395/E1C0X3 SUBFAMILY NOT NAMED (PTHR22826:SF50) Cellular defense response 1.08 24 LRP11 U ENSGALG00000019987/E1C5C3 LOW‐DENSITY LIPOPROTEIN RECEPTOR‐RELATED PROTEIN 11 Response to external stimulus 0.94 (PTHR10083:SF197) 25 TNKS2 U ENSGALG00000014614/F1P4A9 TANKYRASE‐2 (PTHR24180:SF11) Response to stress 0.82 26 LOXL2 ENSGALG00000000402/E1C3U7 LYSYL OXIDASE HOMOLOG 2 (PTHR19331:SF10) Cellular defense response 0.77 27 EPHX2 U ENSGALG00000016567/F1NHP2 BIFUNCTIONAL EPOXIDE HYDROLASE 2 (PTHR10992:SF758) Response to toxic substance 0.63 28 KLF10 U ENSGALG00000016063/F1P0C2 KRUEPPEL‐LIKE FACTOR 10 (PTHR23223:SF21) Immune response 0.63 29 FZD7 U ENSGALG00000023536/F1N965 FRIZZLED‐7 (PTHR11309:SF31) 0.57 30 BRAF U ENSGALG00000012865/F1P1L9 SERINE/THREONINE‐PROTEIN KINASE B‐RAF (PTHR23257:SF360) Response to stress 0.53 31 ENSGALG00000014252 ENSGALG00000014252/F1NEQ4 SUBFAMILY NOT NAMED (PTHR11412:SF73) Immune response 3.17 32 LOC771972 ENSGALG00000020972/F1NPR2 WAP FOUR‐DISULFIDE CORE DOMAIN PROTEIN 8 (PTHR10083:SF169) Response to external stimulus 2.49 33 PTX3 U ENSGALG00000009694/F1NYP7 PENTRAXIN‐RELATED PROTEIN PTX3 (PTHR19277:SF28) Immune response, response to stress 2.12 34 SIK1 ENSGALG00000016200/F1NL00 SERINE/THREONINE‐PROTEIN KINASE SIK1 (PTHR24343:SF0) Response to stress 1.79 35 KIAA0247 U ENSGALG00000009428/E1BXY7 PROTEIN 4933426M11RIK (PTHR19325:SF6) Immune response, response to 1.76 external stimulus 36 LOC395991 ENSGALG00000006944/F1NHI6 SUBFAMILY NOT NAMED (PTHR11309:SF12) 1.48 37 PROKR2 ENSGALG00000008741/F1NNL2 PROKINETICIN RECEPTOR 2 (PTHR24242:SF189) Response to stress 1.47 38 ICK U ENSGALG00000016321/E1BTD4 SERINE/THREONINE‐PROTEIN KINASE ICK (PTHR24055:SF150) Response to stress 1.33 39 GPR133 ENSGALG00000002557/E1C2Q6 G‐PROTEIN COUPLED RECEPTOR 133‐RELATED (PTHR12011:SF216) Immune response, response to stress 1.25 40 ETS2 U ENSGALG00000016059/F1P0R7 PROTEIN C‐ETS‐2 (PTHR11849:SF167) Cellular defense response, immune 1.26 response 41 IL13RA2 ENSGALG00000020316/F1NPT6 INTERLEUKIN‐13 RECEPTOR SUBUNIT ALPHA‐2 (PTHR23036:SF89) Immune response 1.04 42 GPR37L1 U ENSGALG00000000607/F1NJ18 ENDOTHELIN B RECEPTOR‐LIKE PROTEIN 2 (PTHR24243:SF33) Response to stress 1.00 43 LPHN2 U ENSGALG00000008871/F1NN37 LATROPHILIN‐2 (PTHR12011:SF61) Immune response, response to stress 0.90 44 PDGFC_CHICK U ENSGALG00000009378/Q9I946 PLATELET‐DERIVED GROWTH FACTOR C (PTHR10127:SF570) Response to external stimulus 0.84 45 EMID2 U ENSGALG00000001752/F1NI34 SUBFAMILY NOT NAMED (PTHR24023:SF402) 0.81 46 MKNK1 ENSGALG00000010440/F1N9J6 MAP KINASE‐INTERACTING SERINE/THREONINE‐PROTEIN KINASE 1 Response to stress 0.80 (PTHR24349:SF101) 47 TSPAN9 U ENSGALG00000014346/E1BT51 TETRASPANIN‐9 (PTHR19282:SF41) Response to external stimulus 0.76 48 SUSD4 U ENSGALG00000009388/F1P041 SUSHI DOMAIN‐CONTAINING PROTEIN 4 (PTHR19325:SF207) Immune response, response to 0.73 external stimulus 49 MOCOS ENSGALG00000013149/F1NQ69 MOLYBDENUM COFACTOR SULFURASE (PTHR14237:SF19) Response to stress 0.69 50 NFATC3 U ENSGALG00000003396/F1NSQ9 NUCLEAR FACTOR OF ACTIVATED T‐CELLS, CYTOPLASMIC 3 Cellular defense response 0.61 (PTHR12533:SF6) 51 GNAT3 ENSGALG00000008427/F1P3R0 GUANINE NUCLEOTIDE‐BINDING PROTEIN G(T) SUBUNIT ALPHA‐3 0.58 (PTHR10218:SF66) 52 COL4A1 ENSGALG00000016841/F1P2R3 COLLAGEN ALPHA‐5(IV) CHAIN (PTHR24023:SF381) 0.57 53 LOC427844 U ENSGALG00000007161/E1C5R5 LEUCINE‐RICH REPEAT SERINE/THREONINE‐PROTEIN KINASE 2 Response to stress 0.52 (PTHR23257:SF417) 54 F2 ENSGALG00000008332/F1NXV6 SUBFAMILY NOT NAMED (PTHR24265:SF82) Response to external stimulus 0.48 55 GSTT1 U ENSGALG00000005204/E1BUB6 GLUTATHIONE S‐TRANSFERASE THETA 3 (PTHR11260:SF177) Response to toxic substance 1.91 56 IL12B ENSGALG00000001409/F1NNW6 INTERLEUKIN‐12 SUBUNIT BETA (PTHR11321:SF0) Cellular defense response, immune 1.73 response 57 TMPRSS2 U ENSGALG00000016144/F1NY88 TRANSMEMBRANE PROTEASE SERINE 2 (PTHR24256:SF94) Response to external stimulus 1.59 58 CNTNAP5 ENSGALG00000011577/F1NW79 CONTACTIN‐ASSOCIATED PROTEIN‐LIKE 5 (PTHR10127:SF605) Response to external stimulus 1.50 59 DNAJB11 ENSGALG00000006564/F1NVY5 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 (PTHR24077:SF210) Response to stress 1.28 60 FRZB ENSGALG00000002763/F1NFU0 SECRETED FRIZZLED‐RELATED PROTEIN 3 (PTHR11309:SF76) 1.06 61 XG U ENSGALG00000016656/E1BYL8 GLYCOPROTEIN XG (PTHR15076:SF4) Cellular defense response 0.95 62 DAB2IP U ENSGALG00000001419/E1BWM9 DISABLED HOMOLOG 2‐INTERACTING PROTEIN (PTHR10194:SF26) 0.92 63 ENSGALG00000023111 U ENSGALG00000023111/E1C2X7 BPI FOLD‐CONTAINING FAMILY C PROTEIN (PTHR10504:SF17) Defense response to bacterium, 0.86 response to stress 64 COL4A5 ENSGALG00000008141/F1NDF5 COLLAGEN ALPHA‐5(IV) CHAIN (PTHR24023:SF381) 0.85 65 TSPAN6 ENSGALG00000006808/E1C857 TETRASPANIN‐6 (PTHR19282:SF169) Response to external stimulus 0.79 66 OSMR ENSGALG00000003747/F1NN77 ONCOSTATIN‐M‐SPECIFIC RECEPTOR SUBUNIT BETA Immune response 0.75 (PTHR23036:SF80) 67 LMO2 U ENSGALG00000000351/F1NU72 RHOMBOTIN‐2 (PTHR24208:SF101) Cellular defense response 0.70 68 COL4A2 ENSGALG00000016843/F1P2Q3 SUBFAMILY NOT NAMED (PTHR24023:SF354) 0.59 69 TXN U ENSGALG00000015704/P08629 THIOREDOXIN (PTHR10438:SF126) Response to stress 0.56 70 CD40 U ENSGALG00000007015/E1C9I3 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5 Cellular defense response, immune 0.54 (PTHR23097:SF103) response 71 CD276 ENSGALG00000001729/F1NZF8 CD276 ANTIGEN (PTHR24100:SF2) Cellular defense response 0.48 72 NOS1 ENSGALG00000008177/E1C799 NITRIC OXIDE SYNTHASE, BRAIN (PTHR19384:SF63) 1.68 73 NPTXR U ENSGALG00000012183/E1BUW1 NEURONAL PENTRAXIN RECEPTOR (PTHR19277:SF94) Immune response, response to stress 1.43 74 ICOSLG U ENSGALG00000016212/F1NKD4 ICOS LIGAND (PTHR24100:SF55) Cellular defense response 1.13 75 MCF2L ENSGALG00000016834/E1BT68 GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS (PTHR22826:SF115) Cellular defense response, immune 0.94 response 76 VEGFA ENSGALG00000010290/F1NAQ1 VASCULAR ENDOTHELIAL GROWTH FACTOR A (PTHR12025:SF5) Response to stress 0.88 77 SIK2 U ENSGALG00000000312/E1C5R4 SERINE/THREONINE‐PROTEIN KINASE SIK2 (PTHR24343:SF145) Response to stress 0.62 78 LOC428144 U ENSGALG00000004337/E1BWZ8 SUBFAMILY NOT NAMED (PTHR24243:SF119) Response to stress 0.56 79 Q5ZJ46_CHICK U ENSGALG00000015763/Q5ZJ46 GA‐BINDING PROTEIN ALPHA CHAIN (PTHR11849:SF28) Cellular defense response 0.49 80 NCK2 U ENSGALG00000016799/F1P4Q4 CYTOPLASMIC PROTEIN NCK2 (PTHR22820:SF29) Cellular defense response 0.45 81 COCH_CHICK ENSGALG00000009920/O42163 COCHLIN (PTHR22992:SF84) Response to external stimulus 3.36 82 F13A1 ENSGALG00000012802/F1NTJ0 COAGULATION FACTOR XIII A CHAIN