thoraxjnl_65_1S_cover.qxd 6/29/10 3:38 PM Page 1 65 July 2010 Vol 65 Supplement I Vol 65 Supplement I Pages i1–i58 THORAX ThoraxAN INTERNATIONAL JOURNAL OF RESPIRATORY MEDICINE Guideline for non-CF Bronchiectasis British Thoracic Society Bronchiectasis (non-CF) Guideline Group July 2010 thorax.bmj.com Aims and Scope: Thorax enjoys an enviable AN INTERNATIONAL JOURNAL OF RESPIRATORY MEDICINE and longstanding reputation for publishing Journal of the British Thoracic Society clinical and experimental research articles Editor-in-Chief J A Wedzicha (UK) covering many disciplines, including Editor S L Johnston (UK) pathology, immunology and surgery Associate Editors J S Brown (UK) P M A Calverley (UK) International Advisory Board Contact Details M Dusmet (UK) Editorial Office J S Elborn (N Ireland) N Ambrosino (Italy) A Morice (UK) J N Baraniuk (USA) R Panettieri (USA) BMJ Publishing Group Ltd, BMA House, Tavistock A J Fisher (UK) Square London, WC1H 9JR, UK P J Barnes (UK) A Papi (Italy) J M FitzGerald (Canada) T: +44 (0)20 7383 6168 C R W Beasley (New Zealand) N G Papadopoulos (Greece) J A Fleetham (Canada) F: +44 (0)20 7383 6668 J R Britton (UK) M R Partridge (UK) N M Foley (UK) E: [email protected] I Hall (UK) A S Buist (USA) I D Pavord (UK) J R Hurst (UK) E R Chilvers (UK) M G Pearson (UK) R Hubbard (UK) S-H Cho (Korea) T A E Platts Mills (USA) Permissions D A Lomas (UK) S-E Dahlen (Sweden) L Restrick (UK) See http://journals.bmj.com/misc/permissions.dtl D M Mannino (USA) G C Donaldson (UK) D S Robinson (UK) M W Elliott (UK) R M Rudd (UK) F D Martinez (USA) Supplement Enquiries Y Fukuchi (Japan) T A R Seemungal (Trinidad & Tobago) C Robertson (Australia) T: +44 (0)20 7383 6057 B Schonhofer (Germany) D M Geddes (UK) S Sethi (USA) F: +44 (0)20 7554 6795 G A Silvestri (USA) P Goldstraw (UK) T Sethi (UK) E: [email protected] G I Town (New Zealand) R Goldstein (Canada) A K Simonds (UK) M K B Whyte (UK) C Griffiths (UK) P Sliwinski (Poland) J C Hogg (Canada) R A Stockley (UK) For ALL subscription enquiries and orders Statistical Editors S T Holgate (UK) J K Stoller (USA) T: +44 (0)20 7383 6270 J Gibson (UK) P Hopewell (USA) M J Tobin (USA) F: +44 (0)20 7383 6402 L Tata (UK) M Ichinose (Japan) A Torres (Spain) E: [email protected] Images Editors A Kendrick (UK) J Vestbo (Denmark) http://group.bmj.com/group/customerservice/ J M FitzGerald (Canada) T King (USA) E H Walters (Australia) journalhelp/journalhelp J R Mayo (Canada) A J Knox (UK) S T Weiss (USA) J C Hogg (Canada) C K W Lai (China) A Wells (UK) Advertising Letters Editor G J Laurent (UK) JW Wilson (Australia) T: +44 (0)20 7383 6386 J R Hurst (UK) P LeSouef (Australia) A A Woodcock (UK) F: +44 (0)20 7383 6556 Lung Alert Editors W MacNee (UK) M Woodhead (UK) E: [email protected] http://group.bmj.com/group/advertising A Bhowmik (UK) C Mayaud (France) R Zuwallack (USA) J Quint (UK) J Moore-Gillon (UK) Editor, BMJ President, British Thoracic Author Reprints Society Reprints Administrator P Corris T: +44 (0)20 7383 6305 Subscription Information F: +44 (0)207 554 6185 Production Editor E: [email protected] Julia Dimitriou Thorax is published monthly (subscribers receive all supplements) Journal Manager Commercial Reprints (except USA & Canada) Claire Folkes Institutional Rates Personal Rates Nadia Gurney-Randall Publisher 2010 2010 T: +44 (0)20 8445 5825 Julie Solomon M: +44 (0)7866 262344 Print (includes online access at Guidelines for Authors and Print F: +44 (0)20 8445 5870 £491; US$957; 663 no additional cost) E: [email protected] Reviewers £209; US$408; 282 Full instructions are available online Online at http://thorax.bmj.com/ifora. 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F: +44 (0)20 7831 8766 Residents of some EC countries must pay VAT; for details call us or visit E: [email protected] http://group.bmj.com/group/subs-sales/subscriptions/subs-vat http://www.brit-thoracic.org.uk/index.html thoraxjnl_65_1S_titlepage.qxd 6/21/10 6:58 PM Page 1 M C Pasteur, D Bilton, A T Hill On behalf of the British Thoracic Society Bronchiectasis (non-CF) Guideline Group: a sub-group of the British Thoracic Society Standards of Care Committee Contents Volume 65 Issue Suppl I | THORAX July 2010 British Thoracic Society guideline for non-CF bronchiectasis i1 Summary of recommendations Clinical presentation of bronchiectasis Journal of the British Thoracic Society What are the symptoms and signs of Impact Factor: 7.04 Editor-in-Chief i6 Section 1: Introduction bronchiectasis in children? J A Wedzicha (UK) Reason for BTS Bronchiectasis Guideline What symptoms and signs should be assessed Editor in an adult with bronchiectasis? S L Johnston (UK) Guideline Group members Associate Editors How has the Guideline been designed? Investigations directed at underlying J S Brown (UK) J R Hurst (UK) P M A Calverley (UK) D A Lomas (UK) Definition cause M Dusmet (UK) D M Mannino (USA) Why should the underlying cause of J S Elborn (N Ireland) F D Martinez (USA) Methods A J Fisher (UK) C Robertson (Australia) bronchiectasis be established? J M FitzGerald (Canada) B Schonhofer (Germany) J A Fleetham (Canada) G A Silvestri (USA) How common is bronchiectasis in adults and What blood tests should be performed? N M Foley (UK) G I Town (New Zealand) children in the 21st century? I Hall (UK) M K B Whyte (UK) What immunological tests should be done on R Hubbard (UK) What are the pathology and underlying causes? Statistical Editors all patients? L Tata (UK) What is the outlook for these patients? What are the second-line immunological J Gibson (UK) investigations and when should they be Images Editors i8 Section 2: Background and causes J M FitzGerald (Canada) performed? J R Mayo (Canada) Causes and associations When should patients have gastrointestinal J C Hogg (Canada) What underlying causes and associations investigations? Letters Editor should be looked for when investigating When should patients have investigations to J R Hurst (UK) a patient with bronchiectasis? Lung Alert Editors exclude CF? A Bhowmik (UK) Congenital defects of large airways When should patients have tests of ciliary J Quint (UK) Foreign bodies and aspiration President, British Thoracic Society function? What are the best tests to identify P Corris What is the current relevance of previous ciliary defects? Editorial Office severe lower respiratory tract infections to What are the indications for bronchoscopy? BMJ Publishing Group Ltd, BMA House, patients with bronchiectasis? Tavistock Square, London WC1H 9JR, UK Radiological investigations T: +44 (0)20 7383 6147 Mycobacterium tuberculosis and opportunist F: +44 (0)20 7383 6668 mycobacteria What are the important modalities for imaging E: [email protected] bronchiectasis? Immune deficiency and bronchiectasis ISSN: 0040-6376 (print) What is the role of chest x-ray ISSN: 1468-3296 (online) What is the relationship of other airway What is the role of HRCT? Disclaimer: Thorax is owned and published by the diseases to bronchiectasis? British Thoracic Society and BMJ Publishing Group What is an optimum HRCT protocol for defining Ltd, a wholly owned subsidiary of the British Medical What is the relationship of bronchiectasis to Association. The owners grant editorial freedom to bronchiectasis? the Editor of Thorax. cystic fibrosis (CF)? Thorax follows guidelines on editorial What are the HRCT features of bronchiectasis? independence produced by the World Association Which connective tissue disorders are of Medical Editors and the code on good associated with bronchiectasis? Can HRCT identify features of specific causes? publication practice of the Committee on Publication Ethics. Inflammatory bowel diseases How are HRCT changes related to lung Thorax is intended for medical professionals and is provided without warranty, express or implied. function? Statements in the Journal are there sponsibility of Disorders of ciliary function their authors and advertisers and not authors’ How often should radiological investigations be institutions, the BMJ Publishing Group Ltd, the Is a1-antitrypsin deficiency a cause of British Thoracic Society or the BMA unless otherwise repeated? specified or determined by law. Acceptance of bronchiectasis? advertising does not imply endorsement. Radiology in children To the fullest extent permitted by law, the BMJ Yellow nail syndrome Publishing Group Ltd shall not be liable for any loss, What scoring systems should be used for injury or damage resulting from the use of Thorax The upper respiratory tract in bronchiectasis or any information in it whether based on contract, research? tort or otherwise.