Covid-19 Results Briefing

Covid-19 Results Briefing

Brazil COVID-19 RESULTS BRIEFING COVID-19 Results Briefing Brazil February 25, 2021 This document contains summary information on the latest projections from the IHME model on COVID-19 in Brazil. The model was run on February 24, 2021 with data through February 22, 2021. Current situation • Daily reported cases in the last week decreased to 44,200 per day on average compared to 44,800 the week before (Figure 1). • Daily deaths in the last week increased to 1,070 per day on average compared to 1,060 the week before (Figure 2). This makes COVID-19 the number 1 cause of death in Brazil this week (Table 1). • Effective R, computed using cases, hospitalizations, and deaths, is greater than 1 in 9 states (Figure 5). • We estimated that 34% of people in Brazil have been infected as of February 22 (Figure 4). • The daily death rate is greater than 4 per million in 15 states (Figure 3). Trends in drivers of transmission • Mobility last week was 16% lower than the pre-COVID-19 baseline (Figure 7). Mobility was near baseline (within 10%) in Acre, Alagoas, Amapá, Espírito Santo, Goiás, Maranhão, Mato Grosso, Pará, and Tocantins. Mobility was lower than 30% of baseline in Amazonas. • As of February 22 we estimated that 61% of people always wore a mask when leaving their home (Figure 9) compared to 61% last week. Mask use was lower than 50% in Maranhão. • There were 48 diagnostic tests per 100,000 people on February 22 (Figure 11). • In Brazil 85.5% of people say they would accept or would probably accept a vaccine for COVID-19. The fraction of the population who are open to receiving a COVID-19 vaccine ranges from 74% in Roraima to 89% in Sergipe (Figure 14). • In our current reference scenario, we expect that 90.35 million will be vaccinated by June 1st (Figure 15). Projections • In our reference scenario, which represents what we think is most likely to happen, our model projects 363,000 cumulative deaths on June 1, 2021. This represents 115,000 additional deaths from February 22 to June 1st (Figure 16). Daily deaths will peak at 1,420 on April 14, 2021 (Figure 17). • By June 1, 2021, we project that 22,700 lives will be saved by the projected vaccine rollout. • If universal mask coverage (95%) were attained in the next week, our model projects 33,000 fewer cumulative deaths compared to the reference scenario on June 1, 2021 (Figure 16). • Under our worse scenario, our model projects 372,000 cumulative deaths on June 1, 2021 (Figure 16). • Figure 19 compares our reference scenario forecasts to other publicly archived models. Forecasts are widely divergent. • At some point from February through June 1, 25 states will have high or extreme stress on hospital beds (Figure 20). At some point from February through June 1, 27 states will have high or extreme stress on ICU capacity (Figure 21). covid19.healthdata.org 1 Institute for Health Metrics and Evaluation Brazil COVID-19 RESULTS BRIEFING Model updates In this week’s model, we have made five updates. First, new blood bank seroprevalence data from South Africa has strengthened the evidence that the age-standardized infection-fatality ratio (IFR) is much lower in sub-Saharan Africa than previously estimated. Surveys in Kenya and Nigeria had supported this idea, but the more extensive data from South Africa have led us to revise the IFR for all countries in sub-Saharan Africa. This change revised upwards our estimates of the percentage of the population that has been infected in this region. Second, the third round Indian Council of Medical Research serosurvey found a higher level of seroprevalence at the national level than we have been estimating. In this week’s analysis of past levels of infection, we have put more emphasis on this new round of survey data in estimating state-specific IFRs, which in turn is leading to higher estimates of cumulative infection. Third, the winter storm and electricity outages in Texas have had a noticeable impact on case, hospitalization, and death reporting. We have excluded data after the storm from the analysis. Fourth, we have continued to revise our variant scale-up estimates for the past and forecasts for future scale-up. For the past, for countries in Southern Africa without sufficient numbers of isolates sequenced, we have revised the likely start data for B.1.351 based on the scale-up of cases observed in these countries. A similar approach has been taken for Ghana. Newly available sequence data have led to revisions of the timing of the introduction of B.1.1.7, B.1.351, and P1 in select locations. The maps below show our estimates of the prevalence of each variant this week by location. Fifth, we made two changes to the worse scenario. Rather than assuming immediate introduction of new variants B.1.351 or P1 in all locations, we have assumed that the variant spreads to adjacent locations in 21 days, including across national borders. We have also assumed that mask use in those who have been vaccinated will begin declining one month after completed vaccination (rather than the reference scenario that assumes mask will begin declining three months after completed vaccination). covid19.healthdata.org 2 Institute for Health Metrics and Evaluation Brazil COVID-19 RESULTS BRIEFING Figure 1. Reported daily COVID-19 cases 60,000 40,000 Count 20,000 0 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21 Month Daily cases Table 1. Ranking of COVID-19 among the leading causes of mortality this week, assuming uniform deaths of non-COVID causes throughout the year Cause name Weekly deaths Ranking COVID-19 7,480 1 Ischemic heart disease 3,293 2 Stroke 2,519 3 Lower respiratory infections 1,705 4 Chronic obstructive pulmonary disease 1,321 5 Interpersonal violence 1,267 6 Diabetes mellitus 1,257 7 Alzheimer’s disease and other dementias 1,050 8 Road injuries 856 9 Chronic kidney disease 814 10 covid19.healthdata.org 3 Institute for Health Metrics and Evaluation Brazil COVID-19 RESULTS BRIEFING Figure 2. Reported daily COVID-19 deaths 1,500 1,000 Daily deaths 500 0 Jan 20 Feb 20 Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21 covid19.healthdata.org 4 Institute for Health Metrics and Evaluation Brazil COVID-19 RESULTS BRIEFING Figure 3. Daily COVID-19 death rate per 1 million on February 22, 2021 <1 1 to 1.9 2 to 2.9 3 to 3.9 4 to 4.9 5 to 5.9 6 to 6.9 7 to 7.9 >=8 Figure 4. Estimated percent of the population infected with COVID-19 on February 22, 2021 <5 5−9.9 10−14.9 15−19.9 20−24.9 25−29.9 30−34.9 35−39.9 40−44.9 45−49.9 >=50 covid19.healthdata.org 5 Institute for Health Metrics and Evaluation Brazil COVID-19 RESULTS BRIEFING Figure 5. Mean effective R on February 11, 2021. The estimate of effective R is based on the combined analysis of deaths, case reporting, and hospitalizations where available. Current reported cases reflect infections 11-13 days prior, so estimates of effective R can only be made for the recent past. Effective R less than 1 means that transmission should decline, all other things being held the same. <0.89 0.89−0.91 0.92−0.94 0.95−0.96 0.97−0.99 1−1.02 1.03−1.04 1.05−1.07 1.08−1.1 >=1.11 covid19.healthdata.org 6 Institute for Health Metrics and Evaluation Brazil COVID-19 RESULTS BRIEFING Figure 6. Percent of COVID-19 infections detected. This is estimated as the ratio of reported daily COVID-19 cases to estimated daily COVID-19 infections based on the SEIR disease transmission model. 100% 75% 50% 25% Percent of infections detected of infections Percent 0% Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21 Mar 21 Argentina United States of America Colombia Mexico Brazil *Due to measurement errors in cases and testing rates, the infection to detection rate (IDR) can exceed 100% at particular points in time. covid19.healthdata.org 7 Institute for Health Metrics and Evaluation Brazil CRITICAL DRIVERS Critical drivers Table 2. Current mandate implementation All nonessential businesses closed All nonessential businesses restricted businesses Any gatherings Any restricted Mask use School closure home order Stay limits Travel Acre Alagoas Amapá Amazonas Bahia Ceará Distrito Federal Espírito Santo Goiás Maranhão Mato Grosso Mato Grosso do Sul Minas Gerais Paraná Paraíba Pará Pernambuco Piaui Rio Grande do Norte Rio Grande do Sul Rio de Janeiro Rondônia Roraima Santa Catarina Sergipe São Paulo Tocantins Mandate in place No mandate Mandate in place (imposed this week) No mandate (lifted this week) *Not all locations are measured at the subnational level. covid19.healthdata.org 8 Institute for Health Metrics and Evaluation Brazil CRITICAL DRIVERS Figure 7. Trend in mobility as measured through smartphone app use compared to January 2020 baseline 0 −20 −40 −60 Percent reduction from average mobility reduction from average Percent −80 Jan 20 Feb 20Mar 20 Apr 20 May 20 Jun 20 Jul 20 Aug 20 Sep 20 Oct 20 Nov 20 Dec 20 Jan 21 Feb 21Mar 21 Argentina United States of America Colombia Mexico Brazil Figure 8.

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