PATRON JAIMC Prof. Arif Tajammal Principal The Journal of Allama Iqbal Medical College Allama Iqbal Medical College/ Jinnah Hospital July - Sept, 2018, Volume 16, Issue 03 CHIEF EDITOR Rakhshanda Farid Comparison of Recovery Chracteristic of Evoflurane with Isoflurane in Adult 1 Patients Undergoing Cancer Surgery ASSOCIATE EDITOR Aftab Mohsin Aamir Bashir, Muhammad Naveed Azhar,Sajjad Hussain Farhat Naz Irrational Beliefs & Psychological Disturbances: A Cross-Cultural Validation 7 Rashid Zia of Ellis' Hypothesis Zahid Mehmood, Faiza Athar, Rubina Aslam, Kiran Ishfaq MANAGING EDITOR Muhammad Imran Diagnostic Accuracy of Mri In Pituitary Macroadenoma 15 Rafiz Irum, Faiza Siddique, Aisha Asghar, Tashhir Rana, Ahsen Nazir Ahmed STATISTICAL EDITOR Mamoon Akbar Qureshi Trans-Vaginal Ultrasound; An Adjunct to Trans-Abdominal Ultrasound in 19 Ectopic Pregnancy DESIGNING & COMPOSING Talal Publishers Aisha Asghar, Rafia Irum, Ahsen Nazir Ahmed, Syed Saqib Raza Bukhari Biochemical Analysis of Bone Parameters in Patients of Beta Thalassemia 24 INTERNATIONAL ADVISORY BOARD Major Children in Lahore, Pakistan Shoaib Khan (Finland) Saad Usmani (USA) Bashir Ahmad, Farah Deeba, Nadeem Abbas Bilal Ayub (USA) Diagnostic Accuracy of Doppler Ultrasonography for Diagnosis ff Placenta 28 M. Hassan Majeed (USA) Accreta Taking Surgical Findings as Gold Standard Adnan Agha (Saudi Arabia) Uzma Malik Zeeshan Tariq (USA) Diagnostic Accuracy of Mrcp in Differentiating Benign and Malignant Causes 32 Umar Farooq (USA) of Obstructive Jaundice Taking Histopathology as Gold Standard EDITORIAL ADVISORY BOARD Shazia Aman, Muhammad Aamir Khan Frequency and Determinants of Digital Dementia Caused by Overuse of Digital 36 Amatullah Zareen Technology among Students of King Edward Medical University, Lahore Zubair Akram Nadeem Hafeez Butt Sundas Rafique, Suneela Shaukat, Moneeb Ashraf Ayesha Arif Relationship of Urinary Neutrophil Gelatinase Associated Lipocalin with 42 Kashif Iqbal Baseline Proteinuria in Contrast Induced Nephropathy Tariq Rasheed Faiza Javaid, Saima Inam, Marium Shoukat, M. Tahir Saeed, Ahsen Nazir Ahmed Naveed Ashraf Comparison of Ca-125 In First Trimester Of Pregnancy with Non Pregnant 45 Moazzam Nazeer Tarar Woman: Comparitive Cross Sectional Study Tayyab Abbas Asma Fatima, Muhammad Iqbal Javaid, Masuma Ghazanfar, Hifsa Mobeen, Rizwana Aamir Nadeem Nawaz, Ambreen Anwar, Seema Mazhar Tehseen Riaz Effect of Mebendazole Therapy During Pregnancy on Birth Outcome in Patients 50 Muhammd Akram Presenting to Ch. Rehmat Ali Memorial Teaching Hospital Meh-un-Nisa Iram Inam, Shazia Seghal, Nudrat Sohail Ambereen Anwar Rashid Saeed Perception and Practices Regarding Adverse Drug Reaction Among Doctors 54 Muhammad Ashraf Working in Tertiary Care Hospital of Lahore Muhammad Abbas Raza M. Ahmad Alamgir, Mamoon Akbar Qureshi, Muzammil Kataria, Shajeel Akhtar Azim Jahangir Khan Prevalence of Gastric Varices, Their Types and Associations Among Liver 59 Fouzia Ashraf Cirrhosis Patients Shahnaz Akhtar Muhammad Irfan, Haroon Bilal, Farrukh Siddique, Ghulam Mustafa Aftab, Syed Saleem Abbas Jafri Attique Abou Bakr, Aftab Mohsin Shahzad Avais Teratogenic Effects of Deltamethrin on the Developing Mice 63 Tayyab Pasha Shaukat Ali Sayal, Maham Shaukat, Tanvir Akhter, Moeen Din, Asmat Ullah Muhammad Nasrullah Khan Ehsan ur Rehman An Association of Serum Zinc Levels with Febrile Seizures A Case Control 71 Rubina Alsam Study in Children (06 To 36 Months) Ashraf Zia Suffurra Huma, Nosheen Iftikhar, Shabir Ahmed, Nazir Malik, Amna Bibi, Isra Khurshid Khan Khalid Farhat Sultana Bullying among Medical Students of AIMC and its Psychological Effects on 74 Gulraiz Zulfiqar Them Ameena Ashraf Zaka Ullah khan, Zamaraq Manzoor, Saad Tariq, Zermina Azhar, Umme Laila, ZainebTalat PUBLICATION Department of Community Medicine, Allama Iqbal Medical College, Allama Shabbir Ahamed Usmani OFFICE Road, Lahore (Pakistan). Ph: 99231453, E-mail: [email protected], [email protected] JAIMC The Journal of Allama Iqbal Medical College July - Sept, 2018, Volume 16, Issue 03 Bullying among Medical Students of Aimc and its Psychological Effects on them 75 Zaka Ullah khan, Zamaraq Manzoor, Saad Tariq, Zermina Azhar, Umme Laila, ZainebTalat Comparison of Hormonal Assays with Transvaginal Sonography in Polycystic 80 Ovarian Disease Irfan Masood, Naeem Ahmad Khan, Malik Sajjad, Roohi Jabbar, Aamer Nadeem Chaudhary Diagnostic Accuracy of Color Doppler Sonography in the Diagnosis of Thyroid 84 Nodules Malik Sajjad, Naeem Ahmad Khan, Irfan Masood, Aamer Nadeem Chaudhary Prevalence of Depression in Asthmatic Females of Lahore. Pakistan 89 Alishba Mustansar, Sana Batool, FareehaAmjad, Irfan Malik Antimicrobial Susceptibility Pattern of Uropathogens at a Tertiary Care 92 Hospital, Lahore Saima Inam, Muhammad Tahir Saeed, Aqsa Aslam, Buzm Rehman, Iram Awais, Ahsen Nazir Ahmed Clinicopathological Features of Chronic Myeloid Leukemia 99 Masuma Ghazanfar, Muhammad Iqbal Javaid, Rizwana Nawaz, Ambereen Anwar Role of CT (FESS PROTOCOL) in Diagnosis of Fungal Sinusitis in Immuno- 104 copromised Patients Keeping Histopathology as Gold Standard Shazia Aman The Aetiological Factors of Epistaxis in Patients Presented in a Referral 107 Hospital in Saudi Arabia Sajid Rashid Nagra, Ghulam Dastgir Khan, Javed Aslam, Ayesha Hayat Managing Giardia Intestinalis Associated Iron Deficiency Anemia, without 112 Iron Supplementation Mujtaba Hasan Siddiqui, Rizwan Elahi, Omair Farooq Improved Detection of Intrascrotal Pathologies by Colour Doppler Scrotal 117 Ultrasound in Addition to Scrotal Physical Examination in Primary Infertility Cases in Males Yasser Amin, Irfan Nazir, Mujtaba Hasan Siddiqui Association of Serum Cholesterol Levels with Decompensated Chronic Liver 121 Disease Naeem Akbar, Sabeen Farhan, Muhammad Arif Nadeem Frequency of Prediabetes in Patients Infected with Hepatitis C Virus 127 Shahidah Zaman, Asah Ullah Mahmood, Sabeen Farhan, Muhammad Arif Nadeem Frequency of Metabolic Syndrome in Patients Presenting with Cardiac 131 Symptoms and Mean Serum Gammaglutamyltransferase in Patients with or without Metabolic Syndrome Muhammad Waqar ul Hasnain Niaz, Sabeen Farhan, Rana Muhammad Suhail Khan Diagnostic Accuracy of Ultrasound in the Diagnosis of Intussusception in 136 Children Munazza Zafar, Syed Hasnain Abbas, Shahid Manzoor, Fahad Mukhtar, Mustansar Mahmood Warraich PUBLICATION Department of Community Medicine, Allama Iqbal Medical College, Allama Shabbir Ahamed Usmani OFFICE Road, Lahore (Pakistan). Ph: 99231453, E-mail: [email protected], [email protected] ORIGINAL ARTICLE JAIMC COMPARISON OF RECOVERY CHRACTERISTIC OF EVOFLURANE WITH ISOFLURANE IN ADULT PATIENTS UNDERGOING CANCER SURGERY Aamir Bashir1, Muhammad Naveed Azhar2, Sajjad Hussain3 Shaukat Khanum Memorial Cancer Hospital & Research Centre Lahore, Pakistan University Hospital Waterford Ireland, Sulaiman Alhabib Hospital, Rayan Branch, Riyadh ABSTRACT Inhaled volatile anesthetics are used for maintenance of general anesthesia because of their ease of administration, predictable intra-operative hemodynamic changes and recovery characteristics. Rapid recovery from anesthesia is beneficial to ensure quick return of protective airway reflexes, better respiratory drive to improve patient outcome and decrease post-operative complications. We compared recovery characteristics of two inhaled anesthetic agents sevoflurane and isoflurane in adult cancer surgical patients. We hypothesized that sevoflurane has less mean emergence time than isoflurane in adult patients undergoing cancer surgical procedures of intermediate duration. The objective of this study is to compare the mean emergence time of sevoflurane with isoflurane in adult patients. It was a randomized controlled trial conducted in a tertiary care cancer hospital over a period of 6 months. A total of 80 patients equally divided in two group were included. Mean and standard deviation was calculated for emergence time and age, gender was presented in frequency and percentage. Emergence time (in minutes) was compared in both groups and student t- test was applied as a test of significance. Results showed that emergence time of 7.1 ± 1.1 minutes with sevoflurane in group (A) patients and emergence time of 11.1 ± 1.4 minutes with isoflurane in group (B) patients with p value= 0.000. We concluded that Sevoflurane has less mean emergence time than Isoflurane in adult patients undergoing cancer surgical procedures of intermediate duration. Key Words: emergence time, sevoflurane, isoflurane nhaled volatile anesthetics remain the most regional anesthesia (7). The choice of anesthesia and Iwidely used drugs for maintenance of general anesthetics has a profound impact on peri-operative anesthesia because of their ease of administration course, and on post anesthetic recovery of patient(8). through specially designed chambers (vaporizers) The use of new inhalational anesthetic agents is on and predictable intra-operative hemodynamic rise because of their favorable recovery characteris- changes and recovery characteristics(1,2). Rapid tics, measured in terms of emergence time, recovery from general anesthesia is beneficial to extubation time and orientation time (9,10). None of the ensure quick return of protective airway reflexes, currently available inhaled volatile anesthetic agents better respiratory drive to improve patient outcome has all the properties of an ideal inhaled agents (11). and to decrease post-operative complications and Sevoflurane is a rapidly acting, fluorinated ether ultimately decreasing morbidity