Liver Transplantation Liver Transplantation Author Dilip Chakravarty K Division of HPB Surgery and Liver Transplantation Department of General Surgery Chang Gung Memorial Hospital (Linkou) Taipei, Taiwan (ROC) Co-authors WC Lee YY Jan Professor and Chief Professor and Chairman Department of Liver and Transplantation Surgery Department of General Surgery Chang Gung Transplantation Institute (Linkou) Chang Gung Memorial Hospital (Linkou) Chang Gung University Chang Gung University Taipei, Taiwan (ROC) Taipei, Taiwan (ROC) Po-Huang Lee YC Chen Professor of Surgery and Chairman Department of Nephrology Department of Surgery and Chang Gung Memorial Hospital (Linkou) Liver Transplantation Program Chang Gung University National Taiwan University Hospital Taipei, Taiwan (ROC) Taipei, Taiwan (ROC) Foreword Sir Roy Calne ® JAYPEE BROTHERS MEDICAL PUBLISHERS (P) LTD St Louis (USA) • Panama City (Panama) • New Delhi • Ahmedabad • Bengaluru • Chennai Hyderabad • Kochi • Kolkata • Lucknow • Mumbai • Nagpur Published by Jitendar P Vij Jaypee Brothers Medical Publishers (P) Ltd Corporate Office 4838/24 Ansari Road, Daryaganj, New Delhi 110 002, India Phone: +91-11-43574357, Fax: +91-11-43574314 Registered Office B-3 EMCA House, 23/23B Ansari Road, Daryaganj, New Delhi 110 002, India Phones: +91-11-23272143, +91-11-23272703, +91-11-23282021, +91-11-23245672, Rel: +91-11-32558559 Fax: +91-11-23276490, +91-11-23245683 e-mail: [email protected], Website: www.jaypeebrothers.com Branches 2/B, Akruti Society, Jodhpur Gam Road Satellite, Ahmedabad 380 015 Phones: +91-79-26926233, Rel: +91-79-32988717, Fax: +91-79-26927094 e-mail: [email protected] 202 Batavia Chambers, 8 Kumara Krupa Road, Kumara Park East, Bengaluru 560 001 Phones: +91-80-22285971, +91-80-22382956, +91-80-22372664, Rel: +91-80-32714073 Fax: +91-80-22281761 e-mail: [email protected] 282 IIIrd Floor, Khaleel Shirazi Estate, Fountain Plaza, Pantheon Road, Chennai 600 008 Phones: +91-44-28193265, +91-44-28194897, Rel: +91-44-32972089 Fax: +91-44-28193231 e-mail: [email protected] 4-2-1067/1-3, 1st Floor, Balaji Building, Ramkote Cross Road, Hyderabad 500 095 Phones: +91-40-66610020, +91-40-24758498, Rel:+91-40-32940929, Fax:+91-40-24758499 e-mail: [email protected] No. 41/3098, B and B1, Kuruvi Building, St. Vincent Road, Kochi 682 018, Kerala Phones: +91-484-4036109, +91-484-2395739, +91-484-2395740 e-mail: [email protected] 1-A Indian Mirror Street, Wellington Square, Kolkata 700 013 Phones: +91-33-22651926, +91-33-22276404, +91-33-22276415 Fax: +91-33-22656075, e-mail: [email protected] Lekhraj Market III, B-2, Sector-4, Faizabad Road, Indira Nagar, Lucknow 226 016 Phones: +91-522-3040553, +91-522-3040554, e-mail: [email protected] 106 Amit Industrial Estate, 61 Dr SS Rao Road, Near MGM Hospital, Parel, Mumbai 400012 Phones: +91-22-24124863, +91-22-24104532, Rel: +91-22-32926896 Fax: +91-22-24160828 e-mail: [email protected] “KAMALPUSHPA” 38, Reshimbag, Opp. Mohota Science College, Umred Road, Nagpur 440 009 (MS) Phone: Rel: +91-712-3245220, Fax: +91-712-2704275 e-mail: [email protected] North America Office 1745, Pheasant Run Drive, Maryland Heights (Missouri), MO 63043, USA Ph: 001-636-6279734, e-mail: [email protected], [email protected] Central America Office Jaypee-Highlights Medical Publishers Inc., City of Knowledge, Bld. 237, Clayton, Panama City, Panama, Ph: (507)317-0160 Liver Transplantation © 2010, Jaypee Brothers Medical Publishers All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the authors and the publisher. This book has been published in good faith that the material provided by contributors is original. Every effort is made to ensure accuracy of material, but the publisher, printer and authors will not be held responsible for any inadvertent error(s). In case of any dispute, all legal matters are to be settled under Delhi jurisdiction only. First Edition: 2010 ISBN: 978-81-8448-770-1 Typeset at JPBMP typesetting unit Printed at “History tells us that procedures that were inconceivable yesterday, and are barely achievable today, often become the routine of tomorrow.” —Thomas E Starzl Contributors Sir Roy Yorke Calne FRS Miin-Fu Chen MD Arianeb Mehrabi Emeritus Professor of Surgery Professor of Surgery and Department of General, Visceral University of Cambridge and Superintendent, Chang Gung and Transplantation Surgery National University of Singapore Memorial Hospital (Linkou) University of Heidelberg, Im Cambridge, United Kingdom Chang Gung University Neuenheimer Feld 110, 69120 Taipei, Taiwan (ROC) Heidelberg, Germany Masatoshi Makuuchi MD PhD President, Japanese Red Cross Medical Carl-Gustav Groth MD Chao-Long Chen MD Center, 4-1-22 Hiro-o, Shibuya-ku Professor Emeritus Superintendent and Chief Tokyo 150-8935, Japan Transplantation Surgery Department of Liver transplantation Karolinska Institute Chang Gung Memorial Hospital Burckhardt Ringe Fogdevreten 2A SE- 171 77 Kaohsiung Medical Center Department of Surgery Stockholm, Sweden Kaohsiung, Taiwan (ROC) Center for Liver, Biliary and Constantino Fondevila Pancreas Diseases Assistant Professor of Surgery Drexel University College of Medicine Hironori Haga MD Liver Surgery and Liver Transplant Philadelphia, Pennsylvania Associate Professor Department of Surgical Pathology Unit, Institute of Digestive Diseases Pav. 4, 3rd floor, office 19 Sung Gyu Lee Hokkaido University Hospital Hospital Clinic, University of Department of Surgery North 14, West 5, Kita-ku Barcelona, Villarroel 170 Asan Medical Center, Ulsan University Sapporo, 060-8648, Japan Barcelona 08036, Spain 388-1 Poong-Nap Dong Song-Pa Ku, Seoul 138-736, Korea Jordi Bruix Laura Llado Barcelona Clínic Liver Cancer Group Department of Surgery and Hiroto Egawa MD Liver Unit, Hospital Clinic Gastroenterology Organ Transplant Unit Liver Transplant Unit, Hospital U. Kyoto University Hospital CIBERehd, Institute for Biomedical Investigations, August Pi Sunyer Bellvitge, University of Barcelona, 54 Kawara-cho, Sakyo-ku Barcelona, Spain Kyoto-606-8507, Japan Villarroel 170, 08036, Barcelona Catalonia, Spain C/Feixa Llarga s/n, 08907 Hospitalet Ll, Barcelona, Spain Hiroshi Imamura MD Department of Hepatobiliary Nai-Jen Liu MD Jia Fan MD PhD FACS Pancreatic Surgery Chief Liver Cancer Institute Juntendo School of Medicine Division of Therapeutic Endoscopy Zhongshan Hospital, Fudan 2-1-1, Hongo, Bunkyo-ku Department of Hepatogastroenterology University Tokyo 113-8421, Japan Chang Gung Memorial Hospital 180 Feng Lin Road, Shanghai, 200032 Taipei, Taiwan China Seiji Kawasaki MD Department of Hepatobiliary- James Neuberger Pancreatic Surgery, Juntendo Christian S Kuhr MD FACS Liver Unit University, 2-1-1 Director of Transplantation Queen Elizabeth Hospital Hongo Bunkyo-ku, Tokyo 113-8421 Virginia Mason Medical Center Birmingham B15 2TH Japan Seattle, Washington, USA United Kingdom viii Liver Transplantation Sergio Mies MD PhD Ta Sen Yeh MD PhD. Rei Ping Tang MD Associate Professor of Surgery Professor of surgery Chief of Division of Colorectal Sao Paulo Medical School - USP Chang Gung Memorial Hospital Surgery, Department of Surgery Liver Unit, Instituto Dante Pazzanese Director of Surgical Laboratory Chang Gung Memorial Hospital de Cardiologia, São Paulo - SP Chang Gung University Chang Gung University Brazil Taipei, Taiwan Taipei, Taiwan Nicolas Jabbour MD FACS Yao-Ming Wu MD Director Chun-Yen Lin MD DPhil (Oxon) Assistant Professor Nazih Zuhdi Transplant Institute Associate Professor Division of Hepatobiliary surgery INTEGRIS Baptist Medical Center Department of Gastroenterology and Transplantation surgery 3300 NW Expressway, 100-3444 Chang-Gung Memorial Hospital and Department of Surgery Oklahoma City, OK 73112-4481 College of Medicine National Taiwan University Hospital USA Chang-Gung University Taipei, Taiwan Taipei, Taiwan Jaime Bosch MD PhD Chun Nan Yeh MD Liver Unit Chih Chung Lin MD Assistant Professor Institut d’Investigacions Biomediques Division of Liver transplantation Department of General Surgery August Pi i Sunyer (IDIBAPS) Anesthesia Chang Gung Memorial Hospital University of Barcelona Department of Anesthesia Chang Gung University Hospital Clýnic, C.Villarroel 170, Chang Gung Memorial Hospital Linkou, Taoyuan, Taiwan 08036, Barcelona, Spain Chang Gung University Linkou, Taoyuan Taiwan Sung-Yu Chu MD H Ramesh MS MCh FACS FRCS Department of Medical Imaging and Director of Surgical Gastroenterology Interventional Radiology and Liver Transplantation Surgery Ching Sung Lee MD Chang Gung memorial hospital Lakeshore Hospital and Research Division of Therapeutic Endoscopy Linkou, Taoyuan, Taiwan Center, Nettoor, Cochin 682304, Department of Hepatogastroenterology Kerala, India Chang Gung Memorial Hospital Chang Gung University Akshay Kumar Mishra MD Kyu-Bo Sung MD Taipei, Taiwan Deputy Director Department of Radiology (Monitoring and Evaluation/ Asan Medical Center Tsann Long Hwang MD Surveillance) University of Ulsan College of Vice President and Dean AP State AIDS Control Society, Medicine, 388-1, Pungnap-2dong, Department of General Surgery DM and HS Campus Songpa-gu, Seoul 138-736 Chang Gung Memorial Hospital Hyderabad-500095, India Republic of Korea and School of Medicine Chang Gung University SP Samantaray MS Pere Ginès MD Taipei, Taiwan Department