Brain region Type Enriched GO annotation Gene symbol AQR, ARMC7, BTBD9, HACL1, KCTD10, KCTD13, LSM6, MT2A, MYBPC1, POLD2, SRPX, TNFAIP1, USP25, EC Common type DNA replication, Protein catabolic process, Transport USP28, ZMYND19 EC Common type Transport KIAA1549, MBD5, MYO5B, RAB11A, RAB11FIP1, RAB11FIP2, RAB11FIP3, RAB11FIP4, RAB11FIP5, REPS1 ACD, BMP2K, C1orf63, CDK13, CLK3, CYLC2, DDX3Y, FOXJ3, GNL3L, GRPEL1, KIAA2022, MACROD2, Cellular component organization, Kinase activity, Localization, EC Common type NANOG, PAK1IP1, PCBP1, PCMT1, PLOD1, PLOD2, POT1, PRPS1L1, RASGEF1C, RBM15B, RPS7, RSBN1L, Response to stimulus, Transcription SALL1, SEC16A, TDRD6, TERF1, TERF2IP, TINF2, YTHDF1, YTHDF3, ZC3HAV1L, ZNF281 AGFG1, AKR1C3, ARIH1, ARIH2, BCL10, BFAR, BIRC2, BIRC3, BIRC6, BIRC7, C9orf89, CADPS2, CNOT4, DDX58, DIABLO, DTX1, DTX3L, DZIP3, EIF4E2, EML4, EPS15, EXTL3, FBXL19, FCHO2, GPR108, HLTF, HPCA, HTRA2, INF2, ISG15, KIAA1107, KIAA1797, LNX2, LOC147791, LRSAM1, LTN1, MAGEL2, MAP3K1, MARCH5, MARCH7, MC1R, MFN1, MGRN1, MID1, MID2, MKRN1, MKRN2, MKRN3, MRAP, MUL1, NAIP, PARP9, PCNP, PDZRN3, PJA2, PLCD4, RBCK1, RLIM, RMND5B, RNF10, RNF103, RNF11, RNF111, RNF114, DNA repair, Apoptosis, Protein catabolic process, Protein EC Common type RNF115, RNF125, RNF126, RNF128, RNF13, RNF130, RNF138, RNF14, RNF144A, RNF150, RNF165, RNF166, metabolic process, Protein modification process RNF167, RNF181, RNF182, RNF25, RNF26, RNF38, RNF4, RNF41, RSPRY1, SGCE, SH3RF2, STRADB, TMBIM6, TMEM189, TOPORS, TRAF7, TRIM2, TRIM25, TRIM26, TRIM27, TRIM32, TRIM35, TRIM39, TRIM8, UBA52, UBA6, UBE2D1, UBE2D2, UBE2D3, UBE2D4, UBE2E1, UBE2E2, UBE2E3, UBE2G1, UBE2J1, UBE2K, UBE2L3, UBE2L6, UBE2N, UBE2O, UBE2Q2, UBE2R2, UBE2T, UBE2V2, UBE2W, UBE2Z, UBE4A, UBOX5, UBTD1, UEVLD, UGP2, UHRF2, WDR91, XAF1, XIAP, ZNRF1, ZNRF3 ARL4A, BCAS2, CHD8, CSE1L, CTCF, CTNNBL1, KPNA1, KPNA2, KPNA4, PLAG1, PLRG1, PRPF19, RECQL, EC Common type RNA metabolic process, RNA splicing, Transport RPL22, ZNF143 ACCN2, AGAP2, C1orf116, CACNG2, CSPG4, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK3, GRIK5, GRIP1, EC Common type Synaptic transmission, Transport GRIPAP1, GRM3, HOMER1, MLF1, NUMBL, PICK1, PPM1A, RYR1, SDCBP, SOX4, STOML1 EC AD-specific type Cellular biosynthetic process AGL, CNTNAP4, GFPT1, GYG1, GYG2, GYS1, MAST3, NET1, PRKAB2, SH3PXD2A, STIM1, STIM2 EC AD-specific type Glycolysis, Metabolic process, Oxidation reduction DGKE, DLAT, PDHA1, PDHB, PDHX, PDK3 ADAP1, ANP32A, CHRM3, CSNK1A1, DKC1, ERF, LYPLA2, NME1, NUP88, PPP1R14A, PTMA, SET, SETBP1, EC AD-specific type Transport SHQ1, SYT9, THAP7, TNFRSF1B, TRPV1 EC Early-disrupted type Cell cycle, Protein modification process, Transport ACTN4, ATF1, CALM3, CAMK2A, CAMK2B, CAMK2D, MYO10, TRIM3, USP6NL EC Early-disrupted type Glycolysis C16orf45, ENO2, ENSA, HK1, MAP4, SNUPN, TUBA4A, ZNF259 ARHGAP10, ARHGAP44, CBLL1, CCDC104, CDC42, CDC42BPA, CDC42SE1, CDC42SE2, CLIP1, CSN2, Axon guidance, Cellular component organization, Kinase EC Early-disrupted type DOCK9, FGD1, FMNL2, HN1, HPS4, IQGAP1, MCF2L, MYL6B, OLFM2, OPHN1, PAK3, PAK6, PAK7, RAC1, activity ST13 EC Late-disrupted type MRNA stabilization, Protein folding, RNA catabolic process ARCN1, ETF1, GSPT1, GSPT2, MRPL39, PABPC1, PAIP1, PAIP2, PAN2, PAN3, PCBP1, PFDN2, PRMT6, VBP1 ACTB, ACTG1, ACTL6A, ACTR6, ACTR8, BRD8, C20orf20, CAP1, CAP2, CCDC87, CFL1, CFL2, DIP2A, DMAP1, DPCD, DSTN, E2F7, EP400, EPC1, EPC2, FKBP3, GEMIN7, H2AFV, H2AFZ, ING3, INO80, INO80B, Cell polarity, Cellular component movement, Chromatin EC Late-disrupted type INO80C, INO80E, KAT5, MBTD1, MCRS1, MORF4L1, MORF4L2, MRFAP1, MRFAP1L1, NCALD, NFRKB, modification, DNA repair, Growth, Kinase activity, Transcription NUFIP1, PALB2, PCBP1, PCYT1B, PIH1D1, PLA2G4A, PROM1, RUVBL1, RUVBL2, SENP6, SSH1, SSH2, TELO2, TFPT, TRIM68, TTI1, TUBA1A, VPS72, VSNL1, YEATS4, YY1, ZNF232, ZNHIT1 Cellular component organization, DNA repair, Response to EC Late-disrupted type APITD1, C17orf70, ERCC1, ERCC4, FANCF, FANCG, FANCL, HES1, RMI1, RTN2, SAMD3, STRA13, UBL7 stimulus ALDH3A2, ATP1A1, COBRA1, COX2, COX5A, COX5B, COX6B1, COX6C, FXYD1, RDBP, RPS26, SERF2, TH1L, EC Late-disrupted type Transcription TMEM141, TSR2, WHSC2 ARL2, BEST1, C22orf39, CCNG2, CCT2, CCT3, CCT4, CCT5, CCT6A, CCT6B, CCT7, CCT8, CEP350, CLDN12, Biological_process, Cell adhesion, Cell differentiation, DNA CTTNBP2, CTTNBP2NL, ECSIT, FAM40A, FAM40B, FGFR1OP, FGFR1OP2, HECTD1, IER2, IER5, IGBP1, replication, Growth, Kinase activity, Phosphorylation, Protein KLHDC2, MARCH1, MCC, PDCD10, PIM1, PPME1, PPP2CA, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2B, EC Late-disrupted type catabolic process, Protein modification process, Response to PPP2R2D, PPP2R3A, PPP2R4, PPP2R5A, PPP2R5B, PPP2R5C, PPP2R5D, PPP2R5E, PRDX2, PRR14, RAB18, stimulus, Signaling, Small molecule metabolic process RFWD2, SKA2, SKIV2L2, SLMAP, STK25, STRN, STRN3, STRN4, TCP1, TUBA8, ZCCHC8, ZNF136, ZNF295, ZRANB1 Catalytic activity, Cell adhesion, Cell death, Cellular component organization, Membrane protein ectodomain proteolysis, Notch APBA2, APBA3, APBB2, APBB3, APP, BACE1, BGN, CIB1, CLSTN1, ICAM5, KCNIP4, NCSTN, PSEN1, EC Late-disrupted type receptor processing, Protein catabolic process, Protein PSEN2, PSENEN, SLK, YME1L1 processing, Proteolysis, Signaling Cell cycle, Cell division, Cellular component organization, EC Late-disrupted type FRMD4A, NCAPD3, NCAPH2, OLFM1, SMC2, SMC4, SNAP91, TRAF3IP1 Mitosis, Mitotic chromosome condensation ABI1, APBB1, APBB1IP, ASAP1, CHERP, COBL, CPSF6, CPSF7, CYFIP1, CYFIP2, DDX42, DDX46, DHX15, Endocytosis, Nuclear mRNA 3'-splice site recognition, Nuclear DNMBP, EVL, FMNL3, FYB, GAS7, GIN1, HTATSF1, MICALL1, NCK2, NCKAP1, PACSIN1, PACSIN2, PHF5A, EC Late-disrupted type mRNA splicing, via spliceosome, RNA metabolic process, RNA PRMT2, PRPF40A, RAPH1, RBM17, RCC2, RUFY2, SF1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B14, SF3B2, splicing, Response to stimulus SF3B3, SF3B4, SF3B5, SMNDC1, TCERG1, TPM4, TSHZ1, TSHZ2, TSHZ3, VASP, WAS, WASF2, WBP11, WBP4, WIPF2, WIPF3, WWOX, YLPM1 EC Late-disrupted type Sensory perception of taste, Signaling ARHGEF18, GNB1, GNB2, GNB3, GNB4, GNB5, GNG10, GNG13, GNG3, GNG4, GNG5, KCNJ3 ADAT3, ANKRD12, ANLN, ATXN7, ATXN7L3, BRD2, BTAF1, CCDC101, CREM, DRAP1, ENY2, FAM48A, FOXF2, GTF2A1, GTF2A2, GTF2B, GTF2E1, GTF2E2, GTF2F1, GTF2H4, KAT2A, KLF5, KRT2, LAMB2, NFYB, Cell death, Cellular biosynthetic process, Histone H3 EC Late-disrupted type NR1D2, POU3F2, SAP130, SETD7, SND1, SUPT3H, SUPT7L, TADA1, TADA3, TAF1, TAF10, TAF11, TAF12, acetylation, Histone deubiquitination, Transcription TAF1L, TAF2, TAF3, TAF4, TAF4B, TAF5, TAF5L, TAF6, TAF7, TAF9, TAF9B, TBP, TBPL1, TCF12, THY1, TRIM24, TXNDC11, ZNF7 Anterior/posterior pattern formation, Cell proliferation, EC Late-disrupted type BTG1, BTG2, CNOT1, CNOT10, CNOT3, CNOT7, CNOT8, HMGN1, HOPX, HOXB9, PHTF1 Developmental process, Transcription EC Late-disrupted type RNA metabolic process NOVA1, POP1, POP4, POP5, POP7, RPP14, RPP30, RPP38, RPP40 ADRM1, ANKIB1, ASPRV1, C19orf60, CKMT2, CYB5B, DERA, DLD, DSP, DUSP14, HAUS7, HERC3, HERC6, HTR1E, INSIG2, JKAMP, LENG8, MAP3K5, MB, NUB1, PAAF1, PCID2, POTEKP, PSMA1, PSMA2, PSMA4, Cell cycle, Developmental process, Interspecies interaction PSMA6, PSMA7, PSMB2, PSMB3, PSMB5, PSMB6, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, EC Late-disrupted type between organisms, Protein catabolic process PSMC6, PSMD1, PSMD10, PSMD11, PSMD12, PSMD13, PSMD14, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PTPN2, RNF185, RPN1, S100A14, S100A16, SAC3D1, SHFM1, SRXN1, TXN, TXNL1, UBE3C, UBLCP1, UBQLN2, UCHL5, USP14, USP37 Apoptosis, Cell cycle, Cell proliferation, Cellular biosynthetic EC Late-disrupted type CD74, CLEC2L, CRB1, EXT1, EXT2, FIBP, HYOU1, KIAA0528, MIF process, Macrophage activation, Ossification EC Late-disrupted type Cellular component organization, Transport NUP107, NUP37, NUP85, SEC13, SEC16B, SEC31A, SEH1L EC Late-disrupted type Cell cycle, Cell division, Mitosis, Protein modification process CDC42EP3, SEPT2, SEPT6, SEPT7, SEPT9, STMN1 EC Late-disrupted type Transport ALDOA, ALDOC, ATP6V1E1, ATP6V1G1, ATP6V1G2, ATP6V1H Apoptosis, Interspecies interaction between organisms, EC Late-disrupted type BNIP3, BNIP3L, CD47, DOK5, HLA-DPB1, PKMYT1, ROBO2, STEAP3, TMEM11, TRIM13 Response to stimulus, Survival gene product expression EC Late-disrupted type Protein modification process, Transport COG1, COG2, COG3, COG4, COG5, COG6, COG7 EC Late-disrupted type Attachment of GPI anchor to protein GPAA1, PIGK, PIGS, PIGT, ULBP2 EC Late-disrupted type Cellular biosynthetic process, Protein modification process DPM1, DPM2, DPM3, PIGA, PIGC, PIGH, PIGP, PIGQ EC Late-disrupted type Biological_process MPDZ, PLEKHA1, PLEKHA2 BCAP29, BCAP31, CABLES2, CDK3, CDK5, CPLX1, CPLX2, DOC2A, EHD3, ITSN1, OSBP, PRRT2, SCAMP1, Calcium ion-dependent exocytosis, Exocytosis, Membrane SCAMP2, SLC38A2, SLC6A1, SNAP23, SNAP25, SNAP29, SNTG1, SRCIN1, STX11, STX12, STX17, STX1A, EC Late-disrupted type fusion, Secretion, Synaptic transmission, Synaptic vesicle STX1B, STX2, STX3, STX4, STXBP1, STXBP3, STXBP5, SV2C, SYT1, SYT3, TNFRSF21, UNC13B, VAMP1, docking during exocytosis, Transport VAMP2, VAMP3, VAMP7, VAPA, VAPB MRNA cleavage, MRNA polyadenylation, Nuclear mRNA CDC73, CNTNAP2, CPSF1, CPSF2, CPSF3, CPSF4, CSTF1, CSTF2, CSTF2T, CSTF3, CTR9, FIP1L1, HSF2BP, EC Late-disrupted type splicing, via spliceosome, RNA metabolic process, LEO1, NOL8, PAF1, RRAGA, RRAGB, RRAGC, RRAGD, RTF1, SUPT6H, SYMPK, TCEA1, TTC37, WDR61 Transcription Angiogenesis, Cell differentiation, Cell migration, Cell ABI2, ABL1, ABL2, AEBP1, AP3S1, AREG, ARHGAP17,