Final Program April 26-29, 2018 Sheraton Centre Toronto Toronto, Canada CIS-0318-599 CIS 2018 Annual Meeting: Immune Deficiency & Dysregulation North American Conference TABLE OF CONTENTS About CIS . Left General Meeting Information . .3 ABOUT THE CLINICAL Continuing Medical Education Information . .4 IMMUNOLOGY SOCIETY Speaker Disclosures . .5 The Clinical Immunology Society (CIS), Toronto Visitor Information . .7 established in 1986, is the key inter- Schedule at-a-glance . 8. disciplinary organization for the field of Schedule of Events . .10 clinical immunology and is devoted to fostering developments in the science and Exhibit Hall Floor Plan . .19 practice of clinical immunology . CIS is an Exhibitor Listing . .20 international professional organization Poster Listing . 22. which includes more than 800 clinicians, 2018 Annual Meeting Supporters . 32. investigators, and trainees . The mission of CIS is to facilitate education, translational research and novel approaches 2018 ANNUAL MEETING PROGRAM COMMITTEE to therapy in clinical immunology to promote Co-Chairs: Program Committee: excellence in the care of patients with Roshini Sarah Abraham, PhD Megan Cooper, MD, PhD immunologic/inflammatory disorders . Mayo Clinic Washington University in St . Louis The primary objectives and purposes of CIS Rochester, MN St . Louis, MO are to: Troy Torgerson, MD, PhD Alexandra Freeman, MD • facilitate the interchange of ideas and University of Washington NIH information among physicians and other Seattle, WA Bethesda, MD investigators who are concerned with immunological/inflammatory diseases; Elie Haddad, MD, PhD • promote research on the causes and CHU Ste-Justine, University of Montreal mechanisms of diseases relating to the Montreal, QC, Canada immune system and, as a result, to unify Sergio Rosenzweig, MD, PhD concepts of disease pathogenesis; NIH • encourage investigators and clinicians Bethesda, MD to share in their knowledge of Mikko Seppänen, MD, PhD immunologically active drugs and other Helsinki University Central Hospital interventions; Helsinki, Finland • promote application and dissemination of recent advances in biomedical science for Nicola Wright, MD the prevention, diagnosis and treatment Alberta Children’s Hospital of diseases related to immunity and Alberta, AB, Canada inflammation; and • foster excellence in research and medical practice . CONNECT WITH YOUR COLLEAGUES! “LIKE” CIS on Facebook CIS NATIONAL OFFICE Follow us on Twitter @CLINIMMSOC #CIS2018AM #CISinToronto 555 East Wells Street, Suite 1100 Join our Group on LinkedIn Milwaukee, WI 53202 Phone: 414 .224 .8095 Email: info@clinimmsoc .org www .clinimmsoc .org CIS-0318-599 2 FINAL PROGRAM 2018 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference April 26-29, 2018 Toronto, Canada Dear Colleagues, On behalf of the Clinical Immunology Society (CIS), thank you for participating in the 2018 Annual Meeting: Immune Deficiency & Dysregulation North American Conference taking place April 26-29, 2018 at the Sheraton Centre in Toronto, Ontario, Canada . CIS is the key inter-disciplinary organization for the field of clinical immunology and is devoted to fostering developments in the science and practice of clinical immunology . The mission of CIS is to facilitate education, translational research and novel approaches to therapy in clinical immunology and to promote excellence in the care of patients with immunologic/inflammatory disorders . The CIS leadership and the members of the Program Committee have jointly defined our goals and have engaged clinicians and researchers from all types of backgrounds to try to identify the best manner of addressing the critical needs . The primary goal of the Annual Meeting is to provide an exciting venue for the presentation of the newest immune deficiency diseases and the pathogenesis of these defects in molecular terms . The substance of the conference will be cutting edge clinical and basic science research . Another goal is to educate clinicians regarding the state of the art clinical care . We recognize that physicians in training who are likely to see these patients need sessions on the pragmatic aspects of diagnosis and clinical care; thus sessions were designed to provide a stimulating discussion of these issues, while delving into unsolved questions . The final major goal of this conference is to begin to grow the community of physicians who feel competent to see patients with primary immune deficiency . We believe that this is the only way to consolidate and build up a community of physicians and scientists who are working in this area . This Annual Meeting is sure to foster enthusiasm and provide advanced training for physicians and researchers working in the field of primary immune deficiency . The CIS leadership is excited about the 2018 Annual Meeting and we look forward to bringing accomplished clinical researchers together to present what is sure to be outstanding science . We hope you enjoy the meeting! Regards, Roshini Sarah Abraham, PhD Troy Torgerson MD, PhD Mayo Clinic Seattle Children’s Research Institute and University of Washington Rochester, MN Seattle, WA 2018 Program Committee Co-Chair 2018 Program Committee Co-Chair 1 April 26-29, 2018 Toronto, Canada 2018 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference FINAL PROGRAM Submit a Manuscript About the Journal The Journal of Clinical Immunology accepts manuscripts in the areas The Journal of Clinical Immunology of human, basic, and clinical immunology and molecular biology. The is a bimonthly international areas of basic immunology include (but are not limited to) studies of journal that helps researchers lymphocytes, antigen presenting cells, neutrophils, natural killer cells, and academic clinicians keep complement components, immunoglobulins, antibodies, cytokines current on investigative basic and their receptors, immunoregulation, signal transduction, T−cell immunology and diseases receptors, and immunoglobulin genes. Papers on animal models of related to the immune system. human diseases are welcome. Articles dealing with molecular biology This well-established journal related to human diseases are accepted. Special Articles are by invitation only. Case reports will only be considered if they are linked publishes articles on basic, to novel new findings/science or are accompanied by an extensive translational, and clinical review of the relevant medical literature to the findings of the case studies in all aspects of report. immunology, including animal models of human diseases. Authors, editors and reviewers of Journal of Clinical Immunology The OnlineFirst™ feature use our fully web-enabled online manuscript submission and review allows articles to be viewed through the system. To keep the review time as short as possible, we request journal’s website before they are available in the printed journal. authors to submit manuscripts online to the journal’s editorial office. The Journal of Clinical Immunology is the official journal of the Our online manuscript submission and review system offers authors the option to track the progress of the review process of manuscripts Clinical Immunology Society. CIS-0412-365 in real time. To submit a manuscript, please visit http://www.editorialmanager.com/joci/ Editor-in-Chief: Troy R. Torgerson Yildiz Camcioglu Amos Etzioni Emmanuelle Jouanguy Anne Puel Vincent R. Bonagura Seattle Children’s Hospital Istanbul University Ruth Rappaport Children’s INSERM INSERM The Feinstein Institute for Seattle, WA, USA Istanbul, Turkey Hospital Paris, France Paris, France Medical Research Editorial Board: Regis Campos Haifa, Israel Carl June Jose R. Regueiro Hofstra North Shore-LIJ Daniel Adelman Federal University of Bahia Lisa Filipovich University of Pennsylvania Universidad Complutense School of Medicine University of California at San Medical School Cincinnati Children’s Hospital School of Medicine Madrid Manhasset, NY, USA Francisco Salvador, Brazil Medical Center Philadelphia, PA, USA Madrid, Spain Editor-in-Chief: San Francisco, CA, USA Fabio Candotti Cincinnati, Ohio, USA Donald Kohn Janine Reichenbach Jean-Laurent Casanova Waleed Al-Herz National Human Genome Jose Luis Franco University of California at Los University Children’s Hospital The Rockefeller University Kuwait University Research Institute Universidad de Antioquia Angeles Zurich New York, NY, USA Kuwait Bethesda, MD, USA Medellin, Columbia Los Angeles, CA, USA Zurich, Switzerland Associate Editors: Hamoud Al-Moussa Andrew Cant Benzi Garty Necil Kütükçüler John Routes Steven M. Holland King Faisal Specialist Hospital Newcastle Univeristy Schneider Children’s Medical Ege University Medical School Medical College of Wisconsin National Institute of Allergy and Research Center Newcastle upon Tyne, United Center of Israel and Tel Aviv Ege, Turkey Milwaukee, WI, USA and Infectious Diseases Riyadh, Saudi Arabia Kingdom University School of Medicine Harry Malech Reinhard Seger Bethesda, MD, USA Saleh Al-Muhsen Talal Chatila Tel Aviv, Israel National Institute of Allergy University Children’s Hospital Christoph Klein King Saud University University of California at Los Bobby Gaspar and Infectious Diseases Zurich Ludwig Maximilians Riyadh, Saudi Arabia Angeles University College London Bethesda, MD, USA Zurich, Switzerland University Munich Basel K. Al-Ramadi Los Angeles, CA, USA London, United Kingdom Tim Niehues John W. Sleasman Munich, Germany United Arab Emirates Antonio Condino-Neto Andrew Gennery HELIOS