European Cell Death Organization 15 (ECDO) The Jožef Stefan Institute, Ljubljana, October 26-31, 2007, Portoroz, Slovenia ___________________________________________________________________________ Programme and Book of Abstracts This publication is available at the conference website http://www.ecdo.eu/portoroz/index.html Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ No responsibility is assumed by the publisher for any injury and/or damage to persons or property resulting either directly or indirectly from material contained within this book. Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Organisation Local Organisation Boris Turk Department of Biochemistry, Molecular and Structural Biology J. Stefan Institute Jamova 39 SI-1000 Ljubljana, Slovenia Tel. +386 1 477 3772 Fax. +386 1 477 3984 e-mail: [email protected] ECDO Scientific Committee Wilfried Bursch Institute of Cancer Research, Medical University of Vienna, Vienna, Austria Klaus-Michael Debatin University Children's Hospital, Ulm, Germany Wim Declercq VIB/Ghent University, Ghent, Belgium László Fésüs University of Debrecen, Debrecen, Hungary Simone Fulda University Children's Hospital, Ulm, Germany Marie-Lise Gougeon Institut Pasteur, Paris, France Marja Jäättelä Institute for Cancer Biology, Danish Cancer Society, Copenhagen, Denmark Peter Krammer German Cancer Research Centre, Heidelberg, Germany Guido Kroemer Institut Gustave Roussy, Villejuif, France Seamus Martin Trinity College, Dublin, Ireland Gerry Melino MRC Toxicology Unit, Leicester, United Kingdom Mauro Piacentini University of Rome “Tor Vergata”, Rome, Italy Hans-Uwe Simon University of Bern, Bern, Switzerland Zsuzsa Szondy University of Debrecen, Debrecen, Hungary Boris Turk Jozef Stefan Institute, Ljubljana, Slovenia Peter Vandenabeele VIB/Ghent University,Ghent, Belgium Boris Zhivotovsky Karolinska Institutet, Stockholm, Sweden Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Table of Contents Table of Contents Welcome Marie Curie Evaluation form Conference Information Training Course Programme Conference Programme Lecture Abstracts: Invited speakers (alphabetically) Lecture Abstracts: Short Oral Communications (alphabetically) Poster Abstracts (alphabetically) Poster List Authors’ Index Participants’ List Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Welcome Welcome It is my great pleasure and honour to welcome all of you at the 15th 15 th Euroconference on Apoptosis in Portorož. This is the first time that the Euroconference is organized in Slovenia. Although a cell death meeting was never organized in Slovenia, cell death was a regular topic for more then a decade on International Symposia on Proteinase Inhibitors and Biological Control and on International Conferences on Cysteine Proteinases, organized in Slovenia every second year since 1983. The program of this Meeting linking basic science with clinical applications stresses the importance and trends in cell death research. At this year’s meeting there are 400 participants from 6 different continents. I would like to thank all of the invited speakers, poster presenters and participants who contribute to the quality of the Meeting, as well as express my thanks to EC for the financial support within the framework of the Marie Curie Conferences and Training Courses, which have made the meeting possible. At this point I would express my sincere gratitude to ECDO Scientific Board, who made a very attractive program with a lot of space for young researchers, and especially to ECDO Secretary Veronique Vandevoorde for her invaluable work in preparing a very exciting conference. I believe that scientific meetings like this provide a great opportunity to strengthen our knowledge in this area and, by our discussions together, stimulate future research. I wish you a very pleasant stay in Slovenia. October 11, 2007 Boris Turk Chairman of the Conference Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Evaluation form Evaluation form Also this year's Euroconference is organised within the framework of the EC Marie Curie Programme ‘Europtosis’. Thanks to the financial support of the EC, a substantial number of participants received a grant to attend this meeting. In view of this European programme, ECDO would appreciate it very much if you could fill in the evaluation questionnaire online upon your return. This will only take about 5 minutes of your time and the total procedure is outlined on the next page. Thank you for your cooperation! The ECDO board Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Evaluation form 1 Choose the URL: http://webgate.cec.eu.int/sesam/index.do 2. In the left banner, select “ MCA Questionnaires ” 3. The “ Select questionnaire type ” page is presented below. The “Instrument”, “Project type” and “Questionnaire type” options you need to select are filled in on the example 4. “Edit questionnaire” 5. The “ Project identification ” page is presented. The “Project ID’ number you have to fill in is “504454”. 6. After pressing the “ Validate ” button, you will reach the “ MCA Conferences and Training Courses Assessment Questionnaire ”. 7. Please read carefully the instructions, complete the questionnaire, and submit your evaluation by pressing the “submit” button. Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Conference information CONFERENCE VENUE: St. Bernardin Resort & Convention Centre Obala 2 6320 Portoroz Slovenia SCIENTIFIC CORRESPONDENCE (CHAIR) Boris Turk Department of Biochemistry, Molecular and Structural Biology J. Stefan Institute Jamova 39 SI-1000 Ljubljana Slovenia Tel. +386 1 477 3772 Fax. +386 1 477 3984 e-mail: [email protected] ECDO SECRETARIAT Veronique Vandevoorde Department for Molecular Biomedical Research VIB-University of Ghent, Technologiepark 927 9052 Ghent (Zwijnaarde) Belgium Tel. +32-(0)9-3313682 Fax. +32-(0)9-3313511 e-mail: [email protected] [email protected] http://www.ecdo.eu REGISTRATION To collect the conference materials you are kindly requested to register at the Conference Secretariat in the Grand Hotel Bernardin. Opening hours of the registration desk October 26 (Friday) 14:00 – 18.00 October 27 (Saturday) 08.00 – 18.00 Participants are kindly requested to wear their name badge during all events of the meeting. It allows entry to all sessions, welcome reception, meals,.. Supported by EC within the framework of the Marie Curie ___________________________________________________Conferences and Training Courses ________________________ 15 th Euroconference on Apoptosis Conference information CONFERENCE SECRETARIAT If you need any help during the conference you can find the local organiser and the ECDO secretary at the registration desk. They will help you in all practical aspects of conference participation. In case of emergency please call one of these mobile phone numbers: +32-475-783851 (Veronique Vandevoorde) or +386-51348925 (Boris Turk) LECTURE ROOMS All lectures will be given in the Europe Convention Hall on the top floor of the Grand Hotel Bernardin. Poster presentation will take place next to the meeting room. Please visit the information boards at the registration desk for further information on the poster sessions. INTERNET CONNECTION Wireless Internet access is available at the St. Bernardin Conference Center and is paying (a card can be bought in the hotel). Additionally, a few PCs with internet access will be available to the conference delegates. Histrion Hotel has an internet room where you can connect to the Web through one of the available computers. MEALS AND REFRESHMENT Breakfast will be served at the hotel of lodging. Lunches and dinners during the meeting will be served at the Grand Hotel Bernardin for the all participants/hotel guests of the St. Bernardin Hotels. Lunch and dinner time is indicated in the conference programme. Note : • For participants arriving on October 25 or 26 , dinner will be served in the hotel of lodging. The dinner time at the Grand Hotel Bernardin is from 19.00 – 21.00 and at the Histrion Hotel from 18.30 – 21.00. Hotel guests of the Vile Park Hotel can have the dinner at the Histrion Hotel. • On October 27 , dinner has to be taken before the official opening of the meeting. It will be served from 18.30 on. • Gala dinner on Tuesday evening October 30 will start at 19.30. Refreshments are included in the registration fee for all registered participants. INCOMING MESSAGES AND MESSAGE BOARD Messages received by the desk will be posted on the message board located at the registration desk. Participants may also use this board