www.corning.com/lifesciences Corning Life Sciences Selection Guide Issue 6 Trust Corning for Your Research For superior quality and performance in life science research tools, you can count on Corning. Our comprehensive line of advanced products and technologies is designed to meet your evolving needs in cell-based and genomics research. To learn more, please visit www.corning.com/lifesciences, or call 1.800.492.1110. Customers outside the U.S., please call 1.978.442.2200 or contact your local support office (listed below). Corning Incorporated Worldwide India Taiwan United Kingdom Life Sciences Support Offices t 91-124-235 7850 t 886 2-2716-0338 t 0800 376 8660 f 91-124-401 0207 f 886 2-2716-0339 f 0800 279 1117 Corning BV Life Sciences ASIA/PACIFIC Japan All Other European EUROPE Koolhovenlaan 12 Australia t 81 (0) 3-3586 1996/1997 Countries 1119 NE Schiphol Rijk t 61 2-9416-0492 f 81 (0) 3-3586 1291/1292 France t 31 (0) 20 659 60 51 The Netherlands f 61 2-9416-0493 Korea t 0800 916 882 f 31 (0) 20 659 76 73 f 0800 918 636 Corning Incorporated China t 82 2-796-9500 f 82 2-796-9300 Germany LATINAMERICA Life Sciences t 86 21-3222-4666 t 0800 101 1153 Brasil Tower 2, 4th Floor f 86 21-6288-1575 Singapore f 0800 101 2427 t (55-11) 3089-7419 900 Chelmsford St. Hong Kong t 65 6733-6511 The Netherlands f (55-11) 3167-0700 Lowell, MA 01851 t 852-2807-2723 f 65 6861-2913 Mexico t 800.492.1110 f 852-2807-2152 t 31 20 655 79 28 New! t (52-81) 8158-8400 t 978.442.2200 f 31 20 659 76 73 f (52-81) 8313-8589 f 978.442.2476 www.corning.com/lifesciences Online ordering now available 6/08 6M APC CLS–PSG–001-A4-REV6 Corning, Costar, CellBIND, CellCube, CellSTACK, DNA-BIND, Lambda, Octapette, Spin-X, Stripette, Stripwell, Thermowell, Transtar-96, Transwell,, 8-Pette, and 12-Pette are registered trademarks of Corning Incorporated, Corning, NY. Carbo-BIND, CentriStar, E-Cube, Easy Wash, FiltrEX, GAPS, HYPERFlask, NBS, Netwell, Pronto!, RoboFlask, Snapwell, Steri-View, Stripettor, Sulfhydryl-BIND, UltraGAPS, and Universal-BIND are trademarks of Corning Incorporated, Corning, NY. Ultra-Web is a U.S. registered trademark of Donaldson Company, Inc. Possibilities Made Real All other trademarks included in this document are the property of their respective owners. PCR is covered by patents owned by Hoffman-La Roche, Inc., Nutley, NJ. Issue 6 Corning’s products may be used in connection with the manufacture, use and/or analysis of oligonucleotide arrays under patents owned by Oxford Gene Technology Limited or related companies (“OGT”), but Corning does not have the right to pass on a license under any such patents. Therefore, before Corning’s products can be used in connection with the manufacture, use, or analysis of oligonucleotide arrays, the user should first check with OGT as to whether a license is necessary and if so, secure one. To inquire about a license under OGT's oligonucleotide array patents, please contact [email protected]. For information about OGT, please visit its website at www.ogt.co.uk. Corning Incorporated, One Riverfront Plaza, Corning, NY 14831-0001 ©2008 Corning Incorporated Printed in USA Corning is helping to make your research possibilities real with new and innovative products. Introduction We have recently advanced our microplate line to include many enhancmements and new products. Check out Corning is pleased to present our Life Sciences Selection the new 384 well solid, low-volume and Poly-D-Lysine Guide. In this guide,you will find a selection of our microplates, as well as 384 and 1536 well microplates For up-to-date information on Corning Life Sciences’ newest, most innovative and most requested products. with generic bar codes in the Microplates Section. comprehensive range of products and services, go to For more than 150 years, Corning Incorporated has leveraged For up-to-date information on Corning Life Sciences’ its materials science and process engineering expertise to comprehensive range of products and services, go to www.corning.com/lifesciences. collaborate closely with customers worldwide — turning www.corning.com/lifesciences where you can access: what were once only possibilities into breakthrough realities. Q New Products Information Q One such reality is the Corning® Epic® System, a high- Technical Information including: throughput label-free screening platform based on optical - Application Notes biosensor technology.The system performs both biochemical - Instruction Manuals and cell-based drug discovery applications and offers drug - Product Bulletins developers the ability to evaluate promising new drug Q Educational Opportunities targets. It also allows for the observation of direct biological Q Product Catalog Information interactions not previously detectable in high-throughput applications. Q Product Literature Q For hard-to-attach cell lines, Corning offers a number of Complete Distributor Information ® modified or synthetic surfaces including Corning CellBIND For additional product information, please visit ™ Surface, Ultra-Low Attachment, and Ultra-Web Surfaces. www.corning.com/lifesciences, or contact your local If you are trying to prevent or reduce attachment, we offer support office (see back cover). plates, dishes, flasks and the CellSTACK® Culture Chambers with our Ultra-Low Attachment surface. We also offer two Try one of our newest innovations and see if it can new vessel formats, the HYPERFlask™ Cell Culture Vessel help to make your research possibilities real. and Low Profile flask, for conserving incubator space. Grow enough cells in one 1720 cm2 Grow more in vivo-like cells on Corning’s Epic System, the new Improve cell attachment and HYPERFlask Cell Culture Vessel to Ultra-Web™ synthetic surfaces. high-throughput, label-free yield with our Corning CellBIND seed 2,000 microplates. detection technology allows surface – a nonbiological surface researchers to bring drugs to with high oxygen levels. market faster. Contents WHAT’S NEW FROM CORNING ............ iii MICROPLATES .................................... 45 Overview .............................................. 46 ONLINE CELL CULTURE AND ASSAY TRAINING ............................... iv Selecting the Best Microplate . 47 96 Well Microplates ................................... 50 PRODUCT ORDERING INFORMATION ..... v Corning 96 Well Microplate Selection Guide . Foldout 96 Well Assay Microplates . 50 DISTRIBUTORS .................................... v 96 Well Polystyrene Stripwell™ Microplates . 54 96 Well Polypropylene Storage Microplates and CELL CULTURE ..................................... 1 Cluster Tubes . 55 Overview ............................................... 2 384 Well Microplates ................................... 57 3 4 Innovative Cell Culture Surfaces for Corning 8 Well Microplate Selection Guide . Foldout the 21st Century .................................. Foldout 384 Well Assay Microplates . 57 Corning® CellBIND® Surface . 3 384 Well Polystyrene Microplates . 58 Ultra-Low Attachment Surface . 6 384 Well Polypropylene Storage Microplates . 60 Corning Labware with UltraWeb™ Surfaces . .7 1536 Well Microplates .................................. 61 Cell Culture Flasks ...................................... 9 Protein Crystallization Microplates .................... 63 Cell Culture Dishes ..................................... 13 Microplate Accessories ................................. 65 Multiple Well Plates .................................... 15 Lids ................................................ 65 Transwell® Permeable Supports ........................ 20 Storage Mats and Accessories . 65 Culture Tubes .......................................... 25 Robolids . 66 Sealing Tapes . 66 Roller Bottles .......................................... 26 Technical Appendix ................................... 67 CellSTACK® Culture Chambers .......................... 28 Properties of Some Thermoplastics . 67 CellCube® Systems ..................................... 30 Selected Corning Technical Literature . 71 E-Cube® Culture System ................................ 30 Spinner Flasks .......................................... 31 GENOMICS ........................................ 73 Erlenmeyer Flasks ...................................... 36 Overview .............................................. 74 Cell Scrapers and Lifters ................................ 38 Colony Picking, Bacterial Growth, and Storage ......... 75 Pipets ................................................. 99 Purification ............................................ 76 Spatulas and Microspatulas ........................... 112 Quantitation and Detection ........................... 79 Centrifuge Tubes ...................................... 113 DNA Amplification ..................................... 81 Cryogenic Vials and Accessories ....................... 116 Bar Code Customization ............................... 84 Technical Appendix .................................... 39 (continued next page) Corning Cell Culture Surfaces . 39 Characteristics of Corning Plasticware . 41 Chemical Compatibility of Corning Plasticware . 42 Characteristics of Corning Centrifuge Tubes . 42 Online ordering now available at www.corning.com/lifesciences. i Contents (CONTINUED) MICROARRAY ..................................... 85 Storage Bottles ....................................... 109 Overview .............................................. 86 Containers ............................................ 110 Slide Selection Chart ................................... 87 Cylinder ...............................................