Dr. Eyal Nir May, 2015 CURRICULUM VITAE • Personal Details Name: Eyal Nir Date and place of birth: 06-08-1971 Address and telephone number at work: Ben-Gurion University of the Negev, Beer Sheva, Israel; Office: 972(0)8-6428474, Lab: 972(0)8-6428472 Home Address: HaAtad Street, #11, Apartment #14, Tel-Aviv, 66843, Israel, Phone: 972(0)50-6994468 • Education B.Sc. (1994-1997) Hebrew University, Jerusalem, Israel, Chemistry M.Sc. (1998-1999) Hebrew University, Jerusalem, Israel, Physical-Chemistry Name of advisor: Prof. Mattanjah de Vries Title of the Thesis: Building Blocks of DNA, Gas-Phase Research Ph.D. (1999-2003) Hebrew University, Jerusalem, Israel, Physical-Chemistry Name of advisor: Prof. Mattanjah de Vries Title of the Thesis: Building Blocks of DNA, Gas-Phase Research • Employment History 10/2008 – Current: Senior Lecturer, Department of Chemistry, Ben-Gurion University of the Negev 2003 – 2008: Research Associate (Post-doctorate), Department of Chemistry and Biochemistry, University California Los-Angeles (UCLA), USA 2001 – 2002: Researcher, Department of Physical-Chemistry, University of California Santa Barbara (UCSB), USA 1997 – 2001: Teaching Assistant, Chemistry Department, Hebrew University, Israel Dr. Eyal Nir page 2 • Professional Activities Ad-hoc reviewer for peer-reviewed journals Science, Journal of the American Chemical Society, Nano Letters, Angewandte Chemie, ACS-Nano, The Journal of Physical Chemistry (Letters), Physical Chemistry Chemical Physics, Molecules, Nanoscale, PLOS ONE, Methods, Scientific Reports, A • Educational Activities (a) Courses Taught 1. Physical-Chemistry-I course for 2nd year undergraduate pharmacist (2009, 2011, 2012, 2013, 2014, 2015), biologist, geologists, computer science and health science students (2010, 2012, 2013, 2014, 2015) 2. Physical-Chemistry-II course for 3nd year undergraduate pharmacist (2010, 2011, 2012, 2013, 2014, 2015) 3. Physical-Chemistry-Advanced course for 3nd year undergraduate chemists together with Prof. Pines (2009, 2010, 2013, 2014) 4. Physical-Chemistry Lab - A for 2nd year undergraduate chemists (2009, 2011) 5. Physical-Chemistry Lab - B for 3nd year undergraduate chemical engineers (2011, 2014, 2015) 6. Physical-Chemistry Advance Lab - A for 3nd year undergraduate chemists (2010) 7. Condensed-Phase Course for 3nd year undergraduate chemists (2011, 2014 – with Dr. Visoly, 2015) 8. Physical-Chemistry Seminar Coordinator for graduate students (2011) 9. Departmental Seminar Coordinator for graduate students (2013) 10. General and Analytical Chemistry Lab for 1st year undergraduate chemists (2013) (b) Research Students Graduated: Rula Masoud (M.Sc. 2011) Toma Tomov (M.Sc. 2011, continued to doctorate studies in our group) Yaron Berger (M.Sc. 2014, continued to doctorate studies in our group) Roman Tsukanov (Ph.D. 2014, continued post-doctorate research in our group) Noa Plavner (Ph.D. 2015) Dr. Eyal Nir page 3 Current Students and Post-doctorate Toma Tomov, Doctorate studies, since 2011 – NEGEV Fellowship, 2011 Miran Liber, Doctorate studies, since 2011 – MILGAT DAROM Fellowship, 2011 Yaron Berger, Doctorate studies, since 2014 Roman Tsukanov, Post-doctorate, since 2014 Menahem Pirchi, Post-doctorate, since 2014 Michal Pellach, Post-doctorate, since 2015 Dinesh Khara, Post-doctorate, since 2015 Other Alumni Tapasi Sen, Post-doctorate, 2013 • Awards, Citations, Honors, Fellowships (a) Honors, Citation Awards Intel-Dean Prize for Excellent Ph.D. research, 2000, Hebrew University (4000$) (b) Fellowships 1. DFG (Deutsche Forschungs Gemeinschaft), 1999-2002, Ph.D. Fellowshiop (~45,000$) 2. HFSP (Human Frontier Science Program), 2003-2006, Post-doctorate Fellowship (~150,000$) 3. ALON Fellowship, 2009, Young Faculty in Israel (~230,000$) • Scientific Publications - Information is from ISI WEB OF SCIENCE Peer-reviewed papers: 29 Book chapters: 2 Total number of scientific citations, without self-citations: 1857 H-Index: 20 (out of 21 peer-reviewed papers from Ph.D. and post-doctorate studies) (a) Peer-Reviewed Journals (*From BGU) 1. Nir, E.S; Grace, L.T; Brauer, B.C; de Vries, M. S.PI, "REMPI spectroscopy of jot-cooled guanine", Journal of the American Chemical Society, 1999, 121, 4896-4897. (IF = 11.444; JR = 10/148; Q1; Citations = 103) 2. Nir, E.S; Hunziker, H. E.PI; de Vries, M. S.PI, "Fragment-free mass spectrometric analysis with jet cooling VUV photoionisation", Analytical Chemistry, 1999, 71, 1674- 1678. (IF = 5.825; JR = 4/76; Q1; Citations = 41) Dr. Eyal Nir page 4 3. Cohen, R.S; Brauer, B.C; Nir, E.S; Grace, L.T; de Vries, M. S.PI, "Resonance-enhanced multiphoton ionization spectroscopy of dipeptides", Journal of Physical Chemistry A, 2000, 104, 6351-6355. (IF = 2.775; JR = 50/136; Q2; Citations = 83) 4. Nir, E.S; Imhof, P.S; Kleinermanns, K.PI; de Vries, M. S.PI, "REMPI spectroscopy of laser desorbed guanosines", Journal of the American Chemical Society, 2000, 122, 8091-8092. (IF = 11.444; JR = 10/148; Q1; Citations = 54) 5. Nir, E.S; Kleinermanns, K.PI; de Vries, M. S.PI, "Pairing of isolated nucleic-acid bases in the absence of the DNA backbone", NATURE, 2000, 408, 949-951. (IF = 42.351; JR = 1/55; Q1; Citations = 183) 6. Nir, E.S; Janzen, C.S; Imhof, P.S; Kleinermanns, K.PI; de Vries, M. S.PI, "Guanine tautomerism revealed by UV-UV and IR-UV hole burning spectroscopy", Journal of Chemical Physics, 2001, 115, 4604-4611. (IF = 3.122; JR = 8/33; Q1; Citations = 145) 7. Nir, E.S; Kleinermanns, K.PI; Grace, L.T; de Vries, M. S.PI, "On the photochemistry of purine nucleobases", Journal of Physical Chemistry A, 2001, 105, 5106-5110. (IF = 2.775; JR = 50/136; Q2; Citations = 134) 8. Plutzer, C.S; Nir, E.S; de Vries, M. S.PI; Kleinermanns, K.PI, "IR-UV double-resonance spectroscopy of the nucleobase adenine", Physical Chemistry Chemical Physics, 2001, 3, 5466-5469. (IF = 4.198; JR = 33/136; Q1; Citations = 90) 9. Nir, E.S; de Vries, M. S.PI, "Fragmentation of laser-desorbed 9-substituted adenines", International Journal of Mass Spectrometry, 2002, 219, 133-138. (IF = 2.227; JR = 13/33; Q2; Citations = 5) 10. Nir, E.S; Janzen, C.S; Imhof, P.S; Kleinermanns, K.PI; de Vries, M. S.PI, "Pairing of the nucleobases guanine and cytosine in the gas phase studied by IR-UV double- resonance spectroscopy and ab initio calculations", Physical Chemistry Chemical Physics, 2002, 4, 732-739. (IF = 4.198; JR = 33/136; Q1; Citations = 95) 11. Nir, E.S; Janzen, C.S; Imhof, P.S; Kleinermanns, K.PI; de Vries, M. S.PI, "Pairing of the nucleobase guanine studied by IR-UV double-resonance spectroscopy and ab initio calculations", Physical Chemistry Chemical Physics, 2002, 4, 740-750. (IF = 4.198; JR = 33/136; Q1; Citations = 79) 12. Nir, E.S; Muller, M.S; Grace, L.T; de Vries, M. S.PI, "REMPI spectroscopy of cytosine", Chemical Physics Letters, 2002, 355, 59-64.(IF = 1.991; JR= 77/136; Q3; Citations = 98) 13. Nir, E.S; Plutzer, C.S; Kleinermanns, K.PI; de Vries, M. S.PI, "Properties of isolated DNA bases, base pairs and nucleosides examined by laser spectroscopy", European Physical Journal D, 2002, 20, 317-329. (IF = 1.398; JR = 40/82; Q2; Citations = 148) 14. Nir, E.S; Hunig, I.S; Kleinermanns, K.PI; de Vries, M. S.PI, "The nucleobase cytosine and the cytosine dimer investigated by double resonance laser spectroscopy and ab initio calculations", Physical Chemistry Chemical Physics, 2003, 5, 4780-4785. (IF = 4.198; JR = 33/136; Q1; Citations = 55) 15. Plutzer, C.S; Hunig, I.S; Kleinermanns, K.PI; Nir, E.S; de Vries, M. S.PI, "Pairing of isolated nucleobases: Double resonance laser spectroscopy of adenine-thymine", Chemphyschem, 2003, 4, 838-842. (IF = 3.360; JR = 7/33; Q1; Citations = 62) Dr. Eyal Nir page 5 16. Nir, E.S; Hunig, I.S; Kleinermanns, K.PI; de Vries, M. S.PI, "Conformers of guanosines and their vibrations in the electronic ground and excited states, as revealed by double-resonance spectroscopy and ab initio calculations", Chemphyschem, 2004, 5, 131-137. (IF = 3.360; JR = 7/33; Q1; Citations = 32) 17. Abo-Riziq, A.S; Grace, L.T; Nir, E.S; Kabelac, M.S; Hobza, P.PI; de Vries, M. S.PI, "Photochemical selectivity in guanine-cytosine base-pair structures", Proceedings of the National Academy of Sciences of the United States of America, 2005, 102, 20-23. (IF = 9.809; JR = 4/55; Q1; Citations = 134) 18. Jager, M.PD; Nir, E.PD; Weiss, S.PI, "Site-specific labeling of proteins for single- molecule FRET by combining chemical and enzymatic modification", Protein Science, 2006, 15, 640-646. (IF = 2.861; JR = 146/291; Q3; Citations = 27) 19. Nir, E.PD; Michalet, X.C; Hamadani, K. M.S; Laurence, T. A.S; Neuhauser, D.C; Kovchegov, Y.C; Weiss, S.PI, "Shot-noise limited single-molecule FRET histograms: Comparison between theory and experiments", Journal of Physical Chemistry B, 2006, 110, 22103-22124. (IF = 3.377; JR = 39/136; Q2; Citations = 119) 20. Kong, X. X.S; Nir, E.PD; Hamadani, K.S; Weiss, S.PI, "Photobleaching pathways in single-molecule FRET experiments", Journal of the American Chemical Society, 2007, 129, 4643-4654. (IF = 11.444; JR = 10/148; Q1; Citations = 35) 21. Majumdar, D. S.S; Smirnova, I.T; Kasho, V.T; Nir, E.PD; Kong, X.S; Weiss, S.PI; Kaback, H. R.PI, "Single-molecule FRET reveals sugar-induced conformational dynamics in LacY", Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (31), 12640-12645. (IF = 9.809; JR = 4/55; Q1; Citations = 91) *22. Kovchegov, Y.PI; Meredith, N.S; Nir, E.PI, "Occupation times and Bessel densities", Statistics & Probability Letters, 2010, 80, 104-110. (IF = 0.531; JR = 96/119; Q4; Citations = 0) *23.Tomov, T. E.S; Tsukanov, R.S; Masoud, R.S; Liber, M.S; Plavner, N.S; Nir, E.PI; "Disentangling subpopulations in single-molecule FRET and ALEX experiments with photon distribution analysis", Biophysical Journal, 2012, 102 (5), 1163-1173.