OriGene Technologies, Inc. OriGene Technologies GmbH 9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-888-267-4436 Phone: +49-5221-34606-0 Fax: +1-301-340-8606 Fax: +49-5221-34606-11 [email protected] [email protected] SP4583P Polyclonal Antibody to MRGPRX4 (C-term) - Aff - Purified Alternate names: MRGX4, Mas-related G-protein coupled receptor member X4, SNSR5, SNSR6, Sensory neuron-specific G-protein coupled receptor 5/6 Quantity: 50 µg Concentration: 1.0 mg/ml Background: MRGX4 is an Orphan-A GPCR with an unknown ligand highly similar to other MRG receptors. MRGX4 has been suggested to function in sensory neuron regulation and in the modulation of nociception. MRGX4 expression is confined to the dorsal root and trigeminal ganglia. Uniprot ID: Q96LA9 NCBI: NP_473373.2 GeneID: 117196 Host: Rabbit Immunogen: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MRGPRX3 (67%), MRGPRX1 (67%), ALMS1 (44%). Percent identity with other species by BLAST analysis: Human (100%); Gorilla (89%) Genename: MRGPRX4 Format: State: Liquid Ig fraction Purification: Peptide immunogen affinity column Buffer System: PBS containing 0.09% sodium azide Applications: Immunohistochemistry on Paraffin Sections: 3 - 16 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: Reacts with C-terminus of G Protein-Coupled Receptor MRGX4 (family: GPCR, subfamily: Orphan A). Species Reactivity: Tested: Human, Gorilla Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20170830 1 / 3 SP4583P: Polyclonal Antibody to MRGPRX4 (C-term) - Aff - Purified Pictures: Anti-MRGPRX4 / MRGX4 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat- induced antigen retrieval. Anti-MRGPRX4 / MRGX4 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat- induced antigen retrieval. Anti-MRGPRX4 / MRGX4 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat- induced antigen retrieval. For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20170830 2 / 3 SP4583P: Polyclonal Antibody to MRGPRX4 (C-term) - Aff - Purified Anti-MRGPRX4 / MRGX4 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat- induced antigen retrieval. For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20170830 3 / 3 Powered by TCPDF (www.tcpdf.org).