CIBMTR Scientific July 1, Working Committee 2018 Research Portfolio Milwaukee Campus Minneapolis Campus Medical College of Wisconsin National Marrow Donor Program/ 9200 W Wisconsin Ave, Suite Be The Match – 500 N 5th St C5500 Minneapolis, MN 55401-9959 USA Milwaukee, WI 53226 USA (763) 406-5800 (414) 805-0700 cibmtr.org CIBMTR Scientific Working Committee Research Portfolio: July 1, 2018 TABLE OF CONTENTS 1.0 OVERVIEW .................................................................................................................................................................. 1 1.1 Membership ........................................................................................................................................................... 2 1.2 Leadership .............................................................................................................................................................. 2 1.3 Productivity ............................................................................................................................................................ 3 1.4 How to Get Involved ............................................................................................................................................ 3 2.0 ACUTE LEUKEMIA WORKING COMMITTEE .................................................................................................. 6 2.1 Leadership .............................................................................................................................................................. 6 2.2 Recent Publications ............................................................................................................................................. 6 2.3 Current Studies ...................................................................................................................................................10 3.0 AUTOIMMUNE DISEASES AND CELLULAR THERAPIES WORKING COMMITTEE ........................14 3.1 Leadership ............................................................................................................................................................14 3.2 Recent Publications ...........................................................................................................................................14 3.3 Current Studies ...................................................................................................................................................15 4.0 CHRONIC LEUKEMIA WORKING COMMITTEE ...........................................................................................17 4.1 Leadership ............................................................................................................................................................17 4.2 Recent Publications ...........................................................................................................................................17 4.3 Current Studies ...................................................................................................................................................20 5.0 DONOR HEALTH AND SAFETY WORKING COMMITTEE ........................................................................24 5.1 Leadership ............................................................................................................................................................24 5.2 Recent Publications ...........................................................................................................................................24 5.3 Current Studies ...................................................................................................................................................26 6.0 GRAFT SOURCES AND MANIPULATION WORKING COMMITTEE ......................................................30 6.1 Leadership ............................................................................................................................................................30 6.2 Recent Publications ...........................................................................................................................................30 6.3 Current Studies ...................................................................................................................................................33 7.0 GRAFT-VS-HOST DISEASE WORKING COMMITTEE .................................................................................36 7.1 Leadership ............................................................................................................................................................36 7.2 Recent Publications ...........................................................................................................................................36 7.3 Current Studies ...................................................................................................................................................39 8.0 HEALTH SERVICES AND INTERNATIONAL STUDIES WORKING COMMITTEE .............................42 8.1 Leadership ............................................................................................................................................................42 8.2 Recent Publications ...........................................................................................................................................42 8.3 Current Studies ...................................................................................................................................................45 9.0 IMMUNOBIOLOGY WORKING COMMITTEE ................................................................................................48 9.1 Leadership ............................................................................................................................................................48 9.2 Recent Publications ...........................................................................................................................................48 9.3 Current Studies ...................................................................................................................................................55 2018 Scientific Working Committee Research Portfolio TABLE OF CONTENTS 10.0 INFECTION AND IMMUNE RECONSTITUTION WORKING COMMITTEE .......................................63 10.1 Leadership ..........................................................................................................................................................63 10.2 Recent Publications ........................................................................................................................................63 10.3 Current Studies .................................................................................................................................................64 11.0 LATE EFFECTS AND QUALITY OF LIFE WORKING COMMITTEE .....................................................67 11.1 Leadership ..........................................................................................................................................................67 11.2 Recent Publications ........................................................................................................................................67 11.3 Current Studies .................................................................................................................................................71 12.0 LYMPHOMA WORKING COMMITTEE ..........................................................................................................75 12.1 Leadership ..........................................................................................................................................................75 12.2 Recent Publications ........................................................................................................................................75 12.3 Current Studies .................................................................................................................................................80 13.0 PEDIATRIC CANCER WORKING COMMITTEE ..........................................................................................83 13.1 Leadership ..........................................................................................................................................................83 13.2 Recent Publications ........................................................................................................................................83 13.3 Current Studies .................................................................................................................................................85 14.0 PLASMA CELL DISORDERS AND ADULT SOLID TUMORS WORKING COMMITTEE ..................86 14.1 Leadership ..........................................................................................................................................................86 14.2 Recent Publications ........................................................................................................................................86 14.3 Current Studies .................................................................................................................................................90 15.0 PRIMARY IMMUNE DEFICIENCIES, INBORN ERRORS OF METABOLISM, AND NON- MALIGNANT MARROW DISORDERS WORKING