Health Monitoring Report Latest Monthly Update: 02AUG2021 Location: Greenfield, IN 265I-C.B-17/IcrHsd-Prkdc scid Species: Mouse Most Recent Most Recent Historical Test Virusesf Test Method Test Date Resultsa Resultsa,e Frequencyd Ectromelia Virus 28APR21 ## 0 / 6 0 / 6 Annually Bead Hantaan Virus 28APR21 ## 0 / 6 0 / 6 Annually Bead K Virus 28APR21 ## 0 / 6 0 / 6 Annually ELISA Lactic Dehydrogenase Elevating Virus (LDEV) 28APR21 ## 0 / 6 0 / 6 Annually ELISA Lymphocytic Choriomeningitis Virus (LCM) 28APR21 ## 0 / 6 0 / 6 Annually Bead Minute Virus of Mice (MVM) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Mouse Adenovirus type 1 (FL)(MAD-1) 28APR21 ## 0 / 6 0 / 6 Annually Bead Mouse Adenovirus type 2 (K87)(MAD-2) 28APR21 ## 0 / 6 0 / 6 Annually Bead Mouse Cytomegalovirus (MCMV) 28APR21 ## 0 / 6 0 / 6 Annually Bead Mouse Hepatitis Virus (MHV) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Mouse Parvovirus (MPV) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Mouse Polyoma Virus 28APR21 ## 0 / 6 0 / 6 Annually ELISA Mouse Rotavirus (EDIM) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Mouse Thymic Virus (MTV) 28APR21 ## 0 / 6 0 / 6 Annually IFA Murine Chapparvovirus (MuCPV also known as MKPV) 19FEB21 0 / 9 0 / 21 Annually RT-PCR Murine Norovirus (MNV) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Pneumonia Virus of Mice (PVM) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Respiratory Enteric Virus III (REO 3) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Sendai Virus 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Theiler’s Murine Encephalomyelitis Virus (TMEV, GD7) 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Bacteria, Mycoplasma and Fungi Bordetella bronchiseptica 02AUG21 ## 0 / 8 0 / 56 Quarterly RT-PCR CAR Bacillus 28APR21 ## 0 / 6 0 / 6 Annually ELISA Citrobacter rodentium 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Clostridium piliforme 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Corynebacterium bovis i 02AUG21 ## 0 / 8 0 / 42 Quarterly RT-PCR Corynebacterium kutscheri 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Dermatophytes 28APR21 ## 0 / 12 0 / 28 Quarterly Culture Helicobacter bilis 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Helicobacter hepaticus 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Helicobacter spp 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Klebsiella oxytoca 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Klebsiella pneumoniae 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Mycoplasma pulmonis 02AUG21 ## 0 / 4 0 / 20 Quarterly RT-PCR Pasteurella multocida 02AUG21 ## 0 / 8 0 / 56 Quarterly RT-PCR Pasteurella pneumotropica 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Pneumocystis murina 02AUG21 ## 0 / 12 0 / 56 Quarterly RT-PCR Proteus mirabilis 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Pseudomonas aeruginosa 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Salmonella spp 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Staphylococcus aureus 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Streptobacillus moniliformis 28APR21 ## 0 / 6 0 / 6 Annually RT-PCR Streptococcus spp Group B Beta 02AUG21 ## 0 / 12 0 / 70 Quarterly Culture Streptococcus pneumoniae 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Parasites Ectoparasites 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Endoparasites 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Enteric Protozoan 02AUG21 ## 0 / 12 0 / 70 Quarterly RT-PCR Encephalitozoon cuniculi 28APR21 ## 0 / 6 0 / 6 Annually ELISA Pathological Lesions Gross Exam 28APR21 ## 0 / 12 0 / 28 Annually Pathology Testing Laboratory: ENVIGO RMS Srl Mutant Report Released: 06AUG2021 C.B-17/IcrHsd-Prkdc scid Date Isolator Populated: Varies by Isolator Species Within Isolators: Mouse Report Notes: a Data are expressed as number animals positive/number tested. b Data are expressed as number isolators positive/isolators tested. If a single animal tests positive within the isolator, the isolator is considered positive. d Testing intervals are reported per isolator. e Historical results include 18 months cumulative data. f Serology is completed on immune competent sentinel mice. i Hyperkeratosis Associated Corynebacterium Oct Paul E. Knepley, DVM Attending Veterinarian, Envigo RMS North America Envigo + 8520 Allison Pointe Boulevard + Suite 400 + Indianapolis, IN 46250 + envigo.com .