LETTER TO THE MOUNT SINAI HEALTH SYSTEM COMMUNITY LETTER TO THE MOUNT SINAI HEALTH SYSTEM COMMUNITY Dear Friends, Facing the greatest health care challenge of our time, the entire Mount Sinai Health System Australia and Finland, Mount Sinai created a test that detects COVID-19 antibodies in has responded with extraordinary dedication to protect the health and well-being of a person’s blood as early as three days after the onset of coronavirus symptoms. Mount our communities. This is the guiding mission upon which The Mount Sinai Hospital was Sinai physicians have employed the test to transfer antibody-rich plasma from recovered founded 168 years ago, and today, as never before, our physicians and staff are proving COVID-19 patients to boost the immune response of critically ill patients fighting the their commitment to that mission by leading the fight against COVID-19. This is Mount disease, becoming one of the first health systems in the nation to undertake such a program. Sinai’s finest hour. So, it is with great pride that we share with you some of the Health System’s outstanding work at this critical moment in history. Mount Sinai scientists also developed a test that can quickly assess a patient’s inflammatory response to COVID-19, a critical indicator because in severely ill patients the disease often Mount Sinai physicians, nurses, nurse practitioners, respiratory therapists, and medical ignites extreme inflammation that can be fatal. Mount Sinai physicians are relying upon assistants are on the front lines of the COVID-19 battle, courageously risking their own these measurements in a clinical trial that employs a rheumatoid arthritis drug to reduce lives to care for severely ill patients. It is no overstatement to describe these medical inflammation and improve patient outcomes. And, in yet another new treatment approach, professionals as modern American heroes. As a result of their awe-inspiring, tireless Mount Sinai physicians successfully used a blood-clot-busting drug, tPA, as a life-saving effort, Mount Sinai has saved thousands of lives. measure for COVID-19 patients to clear blood clots in their lungs. Supporting our front-line COVID-19 caregivers is a Mount Sinai team that, day after day, Mount Sinai researchers have also learned that SARS-CoV-2, the virus that causes COVID-19, has gone above and beyond the call of duty: brilliant scientists who are introducing new invades the body stealthily, entering cells quietly, and consequently elicits a very muted treatment approaches as they expand our understanding of COVID-19; generous Trustees immune response compared to the flu or other common respiratory viruses when the body who have been invaluable in tapping their contacts and donating time and money to ensure secretes a family of proteins that assemble to prepare for a viral attack. This, Mount Sinai the delivery of essential equipment and to provide food and hotel accommodations for scientists believe, may account for the particularly lethal nature of COVID-19. our hard-working staff; medical and postgraduate students who have selflessly volunteered across the Health System; and housekeepers who are risking exposure to the virus to These COVID-19 insights and innovations come on top of Mount Sinai’s many research initia- ensure a sanitary environment in our hospitals, to name just a few. tives that are harnessing technology to drive new discoveries that will advance our ability to treat different forms of cancers, heart disease, brain disease, and other serious illnesses. Mount Sinai’s traditions of innovation, collaboration, and resourcefulness are serving us well. A team of pulmonologists, anesthesiologists, sleep and critical care specialists, and It is this exceptional work by our faculty, physicians, and scientists, and the expert, Icahn School of Medicine at Mount Sinai students collaborated to repurpose variable compassionate care of our providers, that make Mount Sinai one of the best health positive airway pressure (VPAP) machines normally used for sleep apnea patients into systems in the world. ventilators that can save lives; then, they shared instructions for their innovation with hospitals across the globe. Our facilities team restructured The Mount Sinai Hospital to Of course, Mount Sinai’s all-in response to COVID-19 has come at a financial cost. The triple its number of intensive care unit beds, and reconstructed dozens of rooms into crisis required aggressive spending to handle the onslaught of patients and has caused negative-pressure isolation rooms to prevent the disease from spreading. a significant loss of revenue due to the postponement of all elective surgery and routine doctor visits. Faced with this sudden imbalance, we must maintain Mount Sinai’s financial Researchers at the Icahn School of Medicine at Mount Sinai have been working with urgency health. And, as the COVID-19 crisis has demonstrated, we must ensure that Mount around the clock to unravel the mysteries of COVID-19 and discover effective treatments. Sinai remains a vital health care resource, providing outstanding care while generating In a matter of weeks, they have made substantial progress. Collaborating with scientists in cutting-edge research insights. LETTER TO THE MOUNT SINAI HEALTH SYSTEM COMMUNITY THE BOARDS OF TRUSTEES MOUNT SINAI HEALTH SYSTEM To meet that objective, we are continually investing in computing capability to enable CO-CHAIRMEN Hamilton E. James EX OFFICIOS Mount Sinai to be a leader in revolutionizing health care during what promises to be a Richard A. Friedman Brad S. Karp Michael S. Gross golden age of advances in biomedicine. We are supporting our students with the Enhanced James S. Tisch James L. Kempner Vicki Gross Thomas L. Kempner, Jr. A. Gale Kroeger Scholarship Initiative, ensuring that the cost of a medical education is not a barrier CHAIRMAN EMERITUS Michael Klein Joanne Stone, MD for highly promising individuals seeking a career in medicine. We are investing in Peter W. May Henry R. Kravis infrastructure to ensure that Mount Sinai’s care remains state-of-the-art and to make Eric S. Lane PHYSICIAN REPRESENTATIVES our facilities attractive, modern, and energy-efficient. Our patients should know they Andrew M. Alper John A. Levin Andrew Leibowitz, MD will receive the same exceptional level of compassionate care at all Mount Sinai locations. Glenn R. August Anton Levy I. Michael Leitman, MD None of this can happen without generous, visionary philanthropists. Frank J. Bisignano Marc S. Lipschultz George McKinley, MD Leon D. Black Daniel S. Loeb Richard B. Rosen, MD Jeff T. Blau Kenneth B. Mehlman Mount Sinai’s historic response to the COVID-19 pandemic highlights how valuable every Thomas R. Block Eric Mindich EMERITUS TRUSTEES philanthropic dollar is to the Health System, and how vital Mount Sinai is to New York and Henry M. Calderon Michael Minikes Bobbie Abrams to the world of medicine. With your support, the Mount Sinai Health System will continue Anthony Cancellieri Neil S. Mitchell Charles R. Bronfman to be prepared for any health emergency as we continue to be recognized as one of the very Gerald J. Cardinale Joshua Nash William M. Ellinghaus top academic medical centers in the nation. Edith W. Cooper James Neary Jane Friedman Henry Cornell Alice Netter Jerome R. Goldstein James W. Crystal Bernard W. Nussbaum Richard A. Goldstein While our Crystal Party tents are missing from Central Park this year—appropriately Jean C. Crystal Peter R. Orszag Judah Gribetz replaced by the tents of a Mount Sinai-affiliated emergency field hospital—we look forward Edgar M. Cullman, Jr. Zibby Owens George J. Grumbach, Jr. to celebrating with you at next year’s Crystal Party. Susan R. Cullman Lewis C. Pell Merril M. Halpern Bonnie M. Davis, MD Joel I. Picket Lawrence S. Huntington Thank you very much for your partnership. Eva Andersson Dubin, MD Bettina B. Plevan Lewis P. Jones Glenn Dubin Joseph J. Plumeri Ellen P. Katz Joel S. Ehrenkranz Richard Ravitch Stanley Komaroff Steven G. Einhorn Judith O. Rubin Jo Carole Lauder KENNETH L. DAVIS, MD DENNIS S. CHARNEY, MD RICHARD A. FRIEDMAN JAMES S. TISCH Joseph J. Fennessy Honorable Robert E. Rubin Eugene Mercy, Jr. PRESIDENT AND ANNE AND JOEL CO-CHAIRMEN, CO-CHAIRMEN, CHIEF EXECUTIVE OFFICER, EHRENKRANZ DEAN, BOARDS OF TRUSTEES BOARDS OF TRUSTEES James E. Flynn Joshua Ruch Carl M. Mueller MOUNT SINAI HEALTH SYSTEM ICAHN SCHOOL OF MEDICINE MOUNT SINAI HEALTH SYSTEM MOUNT SINAI HEALTH SYSTEM Eric J. Friedman Eric M. Ruttenberg Joan Sarnoff AT MOUNT SINAI Robert Friedman Alejandro Santo Domingo Edie Schur PRESIDENT FOR ACADEMIC AFFAIRS, Sonia E. Gardner Denise Saul MOUNT SINAI HEALTH SYSTEM Raquel K. Gilinski Robert F. Savage, Jr. List as of 4/6/20 Arne Glimcher Stephen L. Schwartz Donald J. Gogel Thomas W. Strauss David S. Gottesman Michael J. Urfirer Scott Gottlieb, MD Eric Waldman Joshua J. Harris David Windreich Kimberley D. Harris John S. Winkleman John B. Hess William H. Wright II Steven Hochberg David M. Zaslav Carl C. Icahn Michael J. Zimmerman Gail Golden Icahn CRYSTAL PARTY, THURSDAY, MAY 2, 2019 CRYSTAL PARTY, THURSDAY, MAY 2, 2019 MOUNT SINAI CRYSTAL PARTY MOUNT SINAI HEALTH SYSTEM LEADERSHIP HOSPITAL PRESIDENTS COMMITTEE Jeremy Boal, MD and Evan L. Flatow, MD Arthur A. Gianelli and Rebecca Sandler Sharon Gianelli Scott Lorin, MD Richard J. Murphy and Janet Lorin and Mary Murphy BENEFIT CHAIRS Joe and Susan Plumeri Keith L. Marran, Jr. and Tracey Tsai and David L. Reich, MD James C. Tsai, MD MOUNT SINAI HEALTH SYSTEM MOUNT SINAI HEALTH SYSTEM HOSPITALS HOSPITALS THE MOUNT SINAI HOSPITAL MOUNT SINAI BROOKLYN MOUNT SINAI QUEENS MOUNT SINAI SOUTH NASSAU David L. Reich, MD Scott Lorin, MD David L. Reich, MD Richard J. Murphy President, The Mount Sinai Hospital President and Chief Operating Officer, President, Mount Sinai Queens President, Mount Sinai South Nassau www.mountsinai.org/locations/mount-sinai Mount Sinai Brooklyn www.mountsinai.org/locations/queens www.southnassau.org 212-241-6500 www.mountsinai.org/locations/brooklyn 718-932-1000 516-632-3000 212-590-3300 718-252-3000 718-289-3100 718-312-7300 MOUNT SINAI BETH ISRAEL MOUNT SINAI MORNINGSIDE MOUNT SINAI WEST NEW YORK EYE AND EAR AND DOWNTOWN Arthur A.