Supplementary Table 1. Heat-induced alterations in transcript levels of matured oocytes. Average Entrez Gene Amplification Fold Gene ID Affy Probe ID1 Gene Name Symbol Method2 Change Increased in heat-stressed oocytes (n = 22) 100336530 Bt.25923.1.S1_at Formin binding protein 4 (predicted) FNBP4 Total 2.12 615386 Bt.17964.2.A1_s_at Hermansky-Pudlak syndrome 4 HPS4 Total 2.09 SH3 and PX domains 2A, transcript variant Total 2.08 100299286 Bt.3854.1.S1_at SH3PXD2A X2 (predicted) Poly(A) 1.76 540831 Bt.28685.1.S1_at RNA binding motif protein 47 RBM47 Total 1.98 Maturin, neural progenitor differentiation Poly(A) 1.80 615685 Bt.13798.1.S1_at MTURN regulator homolog (Xenopus) Total 1.50 531178 Bt.22384.2.S1_at Cell adhesion molecule 3 CADM3 Total 1.76 507860 Bt.6575.3.A1_at Phosphatidylinositol 4-kinase type 2 alpha PI4K2A Total 1.70 510492 Bt.7385.1.S1_at Rogdi homolog (Drosophila) ROGDI Total 1.70 511754 Bt.10884.2.S1_at Cyclin-dependent kinase 6 CDK6 Poly(A) 1.68 SH3 and PX domains 2A, transcript variant 100299286 Bt.13562.1.S1_at SH3PXD2A Poly(A) 1.65 X2 (predicted) Zinc finger protein 146, transcript variant 100138954 Bt.28639.1.S1_at ZNF146 Poly(A) 1.63 X3 (predicted) Cleavage and polyadenylation specific 282703 Bt.4911.1.S1_at CPSF1 Total 1.61 factor 1, 160kDa 1008848507 Bt.16967.1.A1_at Uncharacterized LOC100848507 LOC100848507 Total 1.61 Stearoyl-CoA desaturase (delta-9- 280924 Bt.4798.1.S2_at SCD Poly(A) 1.59 desaturase) 534273 Bt.24990.2.S1_a_at Ubiquitin specific peptidase 21 USP21 Total 1.59 Cytochrome c oxidase subunit VIa 282199 Bt.23002.1.S1_at COX6A1 Total 1.53 polypeptide 1 Bt.5872.1.S1_at Unknown Poly(A) 1.53 515491 Bt.17754.1.S1_at Transmembrane protein 2 TMEM2 Poly(A) 1.51 ArfGAP with GTPase domain, ankyrin 61630225054 Bt.5481.1.S1_at AGAP3 Total 1.46 repeat &PH domain 3 (predicted) 514720 Bt.24859.1.A1_at Oncostatin M receptor OSMR Poly(A) 1.45 615255 Bt.16111.1.S1_at Glia maturation factor, beta GMFB Poly(A) 1.42 541204 Bt.18789.1.S1_at Activating transcription factor 7 ATF7 Total 1.41 Decreased in heat-stressed oocytes (n = 137) 505376 Bt.13624.2.S1_at F-box protein 15 FBXO15 Poly(A) -1.32 414346 Bt.9791.1.S1_at Peptidylprolyl isomerase F (cyclophilin F) PPIF Total -1.32 Aldo-keto reductase family 1, member B1 317748 Bt.1330.1.S1_at AKR1B1 Poly(A) -1.33 (aldose reductase) 526844 Bt.8925.1.S1_at Dolichol kinase DOLK Poly(A) -1.33 MDS1 and EVI1 complex locus, transcript 532209 Bt.14366.1.S1_at MECOM Poly(A) -1.33 variant X3 (predicted) Menage a trois homolog 1, cyclin H 534176 Bt.2940.1.A1_at MNAT1 Total -1.33 assembly factor (Xenopus laevis) 514440 Bt.26308.2.A1_at RAD18 homolog (S. cerevisiae) RAD18 Poly(A) -1.33 Small nuclear ribonucleoprotein 767873 Bt.11024.1.S1_at SNRPB2 Poly(A) -1.33 polypeptide B SWI/SNF related, actin dependent regulator 540904 Bt.22441.1.S1_at SMARCA2 Poly(A) -1.33 of chromatin, subfamily a, member 2 615512 Bt.23257.1.S1_a_at Cyclin H CCNH Poly(A) -1.34 Family with sequence similarity 98, 530070 Bt.15909.1.S1_at FAM98A Total -1.34 member A Membrane bound O-acyltransferase 541284 Bt. 20276.1.S1_at MBOAT1 Poly(A) -1.34 domain containing 1 Bt.25235.1.A1_at Unknown Poly(A) -1.34 NADH dehydrogenase (ubiquinone) 1, 282289 Bt.67.1.S1_at NDUFC1 Poly(A) -1.34 subcomplex unknown, 1, 6 kDa 539753 Bt.9579.2.S1_a_at Basic transcription factor 3-like 4 BTF3L4 Poly(A) -1.35 507498 Bt.5578.1.S1_at Cytoskeleton associated protein 2-like CKAP2L Poly(A) -1.35 Late endosomal/lysosomal adaptor, MAPK 511903 Bt.4228.1.S1_at LAMTOR4 Poly(A) -1.36 and MTOR activator 4 281555 Bt.5445.2.A1_at Tubulin, beta 2A TUBB2A Poly(A) -1.36 Dishevelled associated activator of 513742 Bt.28836.1.S1_at DAAM1 Total -1.38 morphogenesis 1 Family with sequence similarity 43, 539374 Bt.27193.1.A1_at FAM43A Poly(A) -1.38 member A (predicted) 529245 Bt.13189.2.S1_at Origin recognition complex, subunit 4 ORC4 Poly(A) -1.38 524166 Bt.23857.1.S1_at Ring finger protein 144B RNF144B Poly(A) -1.38 ATP synthase, H+ transporting, 281640 Bt.442.1.S1_at ATP5O Poly(A) -1.39 mitochondrial F1 complex, O subunit 614783 Bt.2277.1.S1_at DAZ associated protein 1 DAZAP1 Poly(A) -1.39 533374 Bt.21270.1.A1_at Gamma-glutamylcyclotransferase GGCT Poly(A) -1.39 Glucosaminyl (N-acetyl) transferase 1, core 281778 Bt.17542.1.S1_at GCNT1 Total -1.39 2 506978 Bt.23546.1.A1_at HEAT repeat containing 1 (predicted) HEATR1 Poly(A) -1.39 Leucine zipper and CTNNBIP1 domain 767886 Bt.22005.1.S1_at LZIC Total -1.39 containing (predicted) 519969 Bt.6078.1.S1 Methylphosphate capping enzyme MEPCE Poly(A) -1.39 514403 Bt.9362.1.S1_at Mitochondrial ribosomal protein L2 MRPL2 Poly(A) -1.39 Family with sequence similarity 149, 533952 Bt.24651.1.A1_at FAM149B1 Total -1.39 member B1 514216 Bt.21087.1.A1_at Transcription factor 19 TCF19 Poly(A) -1.39 100296837 Bt.24408.1.S1_at Cyclin J-like CCNJL Poly(A) -1.39 512684 Bt.10631.1A1_at Zinc finger protein 547-like (LOC512684) ZNF547 Poly(A) -1.39 ATP-binding cassette, sub-family G 536203 Bt.27938.1.A1_at ABCG2 Poly(A) -1.40 (WHITE), member 2 281707 Bt.3907.1.S2_at Coatomer protein complex, subunit zeta 1 COPZ1 Poly(A) -1.40 613720 Bt.727.1.S1_at Coiled-coil domain containing 53 CCDC53 Poly(A) -1.40 Epidermal growth factor receptor pathway 506374 Bt.11266.1.S1_at EPS15L1 Poly(A) -1.40 substrate 15-like 1 504835 Bt.3472.1.A1 Mitochondrial ribosomal protein L1 MRPL1 Poly(A) -1.40 614210 Bt.616.1.S1_at Ring finger protein 166 RNF166 Poly(A) -1.41 Growth hormone inducible transmembrane 404143 Bt.7007.1.S2_at GHITM Total -1.42 protein 617379 Bt.10686.1.S1_at Ring finger protein 170 RNF170 Poly(A) -1.42 Family with sequence similarity 114, Poly(A) -1.43 511198 Bt.12043.1.S1_at FAM114A2 member A2 Total -1.38 5-hydroxymethylcytosine (hmC) binding, 530527 Bt.7639.1.S1_at HMCES Poly(A) -1.43 ES cell-specific 506597 Bt.22676.1.A1_at GPN-loop GTPase 3 GPN3 Total -1.43 TSR1, 20S rRNA accumulation, homolog 510820 Bt.25569.1.A1_at TSR1 Total -1.43 (S. cerevisiae) 540014 Bt.18386.1.A1_at Zinc finger protein 134 (predicted) ZNF134 Poly(A) -1.43 Bt.22096.1.S1_at Unknown Total -1.43 505059 Bt.27918.1.S1_at Wilms tumor 1 interacting protein WT1P Poly(A) -1.43 100141038 Bt.22110.1.S1_at Cytohesin 1 (predicted) CYTH1 Poly(A) -1.44 DEAD (Asp-Glu-Ala-Asp) box polypeptide 504760 Bt.24033.1.A1_at DDX58 Poly(A) -1.44 58, transcript variant X1 (predicted) 534290 Bt.13296.2.A1_at Anoctamin 10 ANO10 Poly(A) -1.45 FAM179B family with sequence similarity 540222 Bt.3990.1.S1_at FAM179B Total -1.45 179, member B LSM6 homolog, U6 small nuclear RNA 615916 Bt.11597.1.S1_at LSM6 Total -1.45 associated (S. cerevisiae) 504477 Bt.28346.1.A1_at Non-SMC condensin I complex, subunit H NCAPH Total -1.45 Solute carrier family 46 (folate transporter), 511097 Bt.7353.1.S1_at SLC46A1 Poly(A) -1.45 member 1 539753 Bt.9579.1.S1_at Basic transcription factor 3-like 4 BTF3L4 Total -1.46 Cholinergic receptor, nicotinic, beta 1 282179 Bt.5107.1.S1_at CHRNB1 Poly(A) -1.46 (muscle) Cleavage and polyadenylation specific 327689 Bt.4077.1.S1_at CPSF2 Poly(A) -1.46 factor 2, 100 kDa Nudix (nucleoside disphosphate linked 614149 Bt.2887.1.S1_at NUDT5 Poly(A) -1.46 moiety X)-type motif 5 281940 Bt.14191.1.A1_at Neurocalcin delta NCALD Poly(A) -1.46 ATP synthase subunit g, mitochondrial-like 515696 Bt.2816.1.S2_at ATP5L Total -1.47 (predicted) 615658 Bt.13563.2.S1_at Calcium modulating ligand CAMLG Poly(A) -1.47 CD59 molecule, complement regulatory 505574 Bt.15782.1.S1_at CD59 Poly(A) -1.47 protein Hematological and neurological expressed 613381 Bt.23106.1.S1_at HN1 Poly(A) -1.47 1 522884 Bt.22067.1.S1_at Timeless homolog (Drosophila) TIMELESS Poly(A) -1.47 508477 Bt.12205.1.S1_at Zinc finger protein 593 ZNF593 Poly(A) -1.47 507512 Bt.3852.1.S1_at O-sialoglycoprotein endopeptidase OSGEP Poly(A) -1.48 511054 Bt.27915.1.S1_at Zinc finger, FYVE domain containing 19 ZFYVE19 Poly(A) -1.48 507711 Bt.21661.1.S1_at Alcohol dehydrogenase, iron containing, 1 ADHFE1 Poly(A) -1.49 613358 Bt.14200.1.A1_at Metallothionein 1E MT1E Poly(A) -1.49 NADH dehydrogenase (ubiquinone) 1, 338046 Bt.21.1.S1_at NDUFC2 Poly(A) -1.49 subcomplex unknown, 2, 14.5 kDa 512377 Bt.9706.2.S1_at RAB5-interacting protein (C13H20orf24) RIP5 Total -1.49 511200 Bt.25097.1.S1_at Guanine monophosphate synthase GMPS Poly(A) -1.50 532671 Bt.25669.1.S1_at Mucolipin 2 MCOLN2 Poly(A) -1.50 280705 Bt.5336.1.A1_a_at Transferrin TF Poly(A) -1.50 541014 Bt.10113.1.S1_at KIAA1143 ortholog KIAA1143 Poly(A) -1.51 Vitamin K epoxide reductase complex, 445422 Bt.1707.1.S1_at VKORC1 Poly(A) -1.51 subunit 1 ATPase, H+ transporting, lysosomal 38 282148 Bt.1575.1.S1_at ATP6V0D1 Poly(A) -1.52 kDa, V0 subunit D1 Polymerase (DNA-directed), delta 539673 Bt.23234.1.S1_at POLDIP2 Poly(A) -1.52 interacting protein 2 522029 Bt.14159.1.A1_at Ribosomal protein L7-like 1 RPL7L1 Poly(A) -1.52 Small nuclear ribonucleoprotein 614553 Bt.2869.1.A1_at SNRPC Poly(A) -1.52 polypeptide C 100295744 Bt.25290.1.A1_at Homeobox D3 (predicted) HOXD3 Total -1.52 Zinc finger with KRAB and SCAN 516885 Bt.7940.1.S1_at ZKSCAN5 Poly(A) -1.52 domains 5 615965 Bt.27808.1.S1_at TatD DNase domain containing e TATDN3 Poly(A) -1.53 512213 Bt.6096.3.A1_at Component of oligomeric golgi complex 2 COG2 Poly(A) -1.53 Poly(A) -1.53 788471 Bt.26608.1.S1_at Ring finger protein 139 (predicted) RNF139 Total -1.43 Roundabout , axon guidance receptor, 534842 Bt.4177.3.A1_at homolog 2 (Drosophila), transcript variant ROBO2 Poly(A) -1.53 X2 (predicted) UDP-Gal:betaGlcNAc beta 1,3- 539027 Bt.16814.1.A1_at galactosyltransferase, polypeptide 1, B3GALT1 Total -1.53 transcript variant X8 497025 Bt.24293.1.A1_at Betaine-homocysteine S-methyltransferase BHMT Total -1.54 Coenzyme Q3 homolog, methyltransferase 540298 Bt.19692.1.S1_at COQ3 Poly(A) -1.54 (S.