Anti-KIF13A (internal region) polyclonal antibody (DPABH-13819) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis. Specificity Cross reacts with many mammalian proteins due to sequence homology. Immunogen Synthetic peptide within Human KIF13A (internal sequence). The exact sequence is proprietary.Database link: KIF13A Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A purified Conjugate Unconjugated Applications IHC-P, WB Format Liquid Size 100 μg Buffer Constituents: 1.21% Tris, 0.75% Glycine, 2% Sucrose Preservative None Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved GENE INFORMATION Gene Name KIF13A kinesin family member 13A [ Homo sapiens ] Official Symbol KIF13A Synonyms KIF13A; kinesin family member 13A; kinesin-like protein KIF13A; bA500C11.2; kinesin-like protein RBKIN; homolog of mouse KIF13A mannose-6-phosphate receptor transporter; RBKIN; FLJ27232; Entrez Gene ID 63971 Protein Refseq NP_001099036 UniProt ID Q9H1H9 Chromosome Location 6p23 Pathway Association of TriC/CCT with target proteins during biosynthesis; Chaperonin-mediated protein folding; Metabolism of proteins; Protein folding; Function ATP binding; microtubule motor activity; nucleotide binding; protein binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.