Medication Guide Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)* *see list of prescription NSAID NSAIDs are used to treat pain, redness, swelling, and heat (inflammation). medicines at the end of this guide WHAT IS THE MOST IMPORTANT INFORMATION YOU SHOULD KNOW ABOUT NSAIDS? NSAIDs can increase the risk of kidney failure, gastrointestinal damage, heart attack or stroke. Heart Kidney Gastrointestinal Attack Damage Damage (GI) Never use right before or You should not take NSAIDs Beware of life-threatening after coronary bypass graft if you have one of these ulcers and bleeding that may ! (CABG) surgery. ! high-risk conditions: ! happen without warning. Your risk† of heart attack or • Kidney disease Your GI risk increases with: stroke increases if: • Diabetes • Taking medicines called corticosteroids • You have heart disease • High blood pressure and anticoagulants • Even with short-term use • You take water pills or pills with • Old age or having poor health † • Smoking and drinking alcohol low dose aspirin does not pose this risk names that end in ‘pril’ or ‘sartan’ Your health risks increase the longer you take NSAIDs WHO SHOULD NOT TAKE NSAIDS? Do talk to your doctor if you: Do not take NSAIDs if you: • have medical conditions • have had an allergic reaction to aspirin or other NSAID • are breastfeeding • are a pregnant woman late in your pregnancy • take more than one medication: show your health provider a list of all of your medicines — some may cause serious side effects when combined with NSAIDs. WHAT ARE SERIOUS SIDE EFFECTS YOU SHOULD KNOW? Call you doctor if you experience: CALL 911 if you experience these symptoms: Signs of stomach problems Heart problems: • stomach pain • shortness of breath or trouble breathing • severe nausea • crushing chest pain • vomit that looks like coffee grounds • swelling in legs • stool is black and sticky like tar Stroke: Signs of allergic reaction • slurred speech • skin rash with blisters • weakness in one part or side of your body Signs of kidney problems Allergic reaction: • increasing blood pressure • swelling of the face or throat • swelling in feet or legs • skin rash with blisters • weakness, trouble breathing • less urination or you stop urinating LESS SERIOUS SIDE EFFECTS Signs of liver problems • gas • heartburn • nausea • skin or eyes look yellow • diarrhea • constipation • dizziness Medication Guide continued... Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)* NSAIDs are used to treat pain, redness, swelling, and heat (inflammation). WHAT HEALTH TIPS SHOULD YOU REMEMBER WHEN TAKING NSAIDS? All health risks Use NSAIDs exactly as prescribed, increase the longer at the lowest dose possible, for the you take NSAIDs. shortest time needed. WHAT NSAID MEDICINES NEED A PRESCRIPTION? Generic name Ibuprofen Naproxen Brand name Motrin, Tab-Profen, Vicoprofen Naprosyn, Anaprox, Anaprox (combined with hydrocodone), DS, EC-Naproxyn, Naprelan, Celecoxib Combunox (combined with Naprapac (copackaged with Celebrex oxycodone) lansoprazole) Diclofenac Indomethacin Oxaprozin Flector, Cataflam, Voltaren, Indocin, Indocin SR, Indo- Daypro Arthrotec (combined with Lemmon, Indomethagan Piroxicam misoprostol) Ketoprofen Feldene Diflunisal Oruvail Sulindac Dolobid Keterolac Clinoril Etodolac Toradol Tolmetin Lodine, Lodine XL Mefenamic Acid Tolectin, Tolectin DS, Tolectin 600 Fenoprofen Ponstel Nalfon, Nalfon 200 Meloxicam Flurbirofen Mobic Ansaid Nabumetone Relafen OVER-THE-COUNTER NSAID MEDICINES Ibuprofen Naproxen Others Motrin, Motrin PM, Advil, Aleve, Aleve PM, Aleve-D Maximum Stength Pamprin, Advil-D, Advil PM, Advil Sinus Doan’s Extra Stength, Congestion and Pain Excedrin PM, Alka Seltzer Plus Cold Author: Amy Barton Pai, PharmD, MHI, FASN, FCCP, FNKF This material is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License Last revised: 05/2018.
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