Chemical Hygiene Plan Revision Date: January 2021 Table of Contents Forward ......................................................................................................................................................... 1 Definitions ..................................................................................................................................................... 1 Section 1: Responsibilities............................................................................................................................. 4 Safety and Risk Management Office ......................................................................................................... 4 Chemical Hygiene Officer (CHO) ............................................................................................................... 4 Department Heads .................................................................................................................................... 5 Principal Investigators or Lab Supervisors ................................................................................................ 5 Laboratory Personnel ................................................................................................................................ 6 Section 2: Laboratory Registration ............................................................................................................... 6 Section 3: Laboratory Inspections ................................................................................................................. 6 Inspection Reports .................................................................................................................................... 7 Lab Inspection Follow-up Process ............................................................................................................. 7 Section 4: Laboratory Close-Out Procedure ................................................................................................. 7 Section 5: Chemical Management ................................................................................................................ 8 Chemical Hazard Information ................................................................................................................... 8 Hazard Symbols and Labeling ................................................................................................................... 8 Table 1: New GHS Labeling Pictograms ................................................................................................ 9 Secondary Container Labeling ................................................................................................................ 10 Safety Data Sheets (SDS) ......................................................................................................................... 10 Exposure Limits ....................................................................................................................................... 11 Chemical Storage .................................................................................................................................... 11 Table 2: Chemical Compatibility Chart ................................................................................................ 12 Chemical Inventory Control .................................................................................................................... 15 Section 6: Time Sensitive Chemicals ........................................................................................................... 15 Peroxide Forming Chemicals ................................................................................................................... 16 Table 3: List of Common Peroxide Formers ........................................................................................ 16 Chloroform .............................................................................................................................................. 18 Shock Sensitive Chemicals ...................................................................................................................... 18 Hazard Controls for Time Sensitive Materials ........................................................................................ 19 Section 7: Dispensing Flammable Liquids ................................................................................................... 19 Section 8: Compressed Gas ......................................................................................................................... 20 Compressed Gas Use Applications .......................................................................................................... 21 Compressed Gas Use in Fume Hoods ..................................................................................................... 21 General Compressed Gas Safety Practices ............................................................................................. 22 Storing Compressed Gas Cylinders ......................................................................................................... 22 Handling Compressed Gas Cylinders ...................................................................................................... 23 Regulators, Tubing, and Piping Connections .......................................................................................... 23 Lecture Gas Bottles ................................................................................................................................. 23 Cryogenic Liquids .................................................................................................................................... 24 Transporting Cryogen Containers ........................................................................................................... 26 Compressed Gas Emergency Procedures ............................................................................................... 26 Compressed Gas Training Requirements ................................................................................................ 27 Dry Ice Handling and Disposal................................................................................................................. 27 Section 9: Controlled Substances................................................................................................................ 28 Section 10: Safety Rules and Best Lab Practices ......................................................................................... 28 Risk Reduction: Hierarchy of Controls .................................................................................................... 28 Working Alone ........................................................................................................................................ 29 Unattended Operations .......................................................................................................................... 30 Housekeeping ......................................................................................................................................... 30 Food, Drink, Tobacco, and Cosmetic Application ................................................................................... 31 Warning Signs and Labels ....................................................................................................................... 31 Glassware Safety ..................................................................................................................................... 31 Mercury Replacement ............................................................................................................................ 32 Maintenance Personnel and Housekeeping ........................................................................................... 32 Section 11: Standard Operating Procedures (SOPs) ................................................................................... 32 High Risk Procedures .............................................................................................................................. 32 Section 12: Personal Protective Equipment (PPE) ...................................................................................... 33 Eye Protection ......................................................................................................................................... 33 Foot Protection ....................................................................................................................................... 36 Hand Protection ...................................................................................................................................... 36 Lab Clothing and Protective Apparel ...................................................................................................... 37 Respirators .............................................................................................................................................. 38 Section 13: Guarding and Shielding for Safety ........................................................................................... 38 Pressurized Systems ................................................................................................................................ 38 Cold Traps and Cryogenic Hazards .......................................................................................................... 39 Section 14: Laboratory