www.bioline.org.br Maximizing Research Impact of Scientific Publications from Developing Countries through Open Access: Experience from Bioline International 科学信息 开放获取战略与政策国际研讨会 Leslie Chan Associate Director, Bioline International University of Toronto at Scarborough International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br History and Mission • Established in 1993 • Explore ways of using ICT to improve scientific communications • Bridge the South-to-North Knowledge gap • Improving visibility, accessibility, and research impact of science from developing countries • Making the “lost” science visible International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br What is Bioline International? • Electronic aggregator of full text journals from developing countries • OAI data provider • Development project - what do readers and authors want? • Aims to influence scholarly communication practices and access to research literature • Will open access improve the visibility and impact of journals from developing countries? International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Three Aspects • Service • Research • Development International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Services • Free electronic publishing, distribution and archiving for participating journals • Technical support for individual and library users • Promotion of participating journals to library consortia and research institutions • Connecting authors and publishers International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Research • Will open access increase journal usage and sustainability? • How do researchers in developing countries use publications and what is their citation pattern? • Does the site of research publication affects the likely impact of research findings on medical practices (Ptolomy project)? International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Development • Value-added services that improve citation and discovery (e.g. Species linking tool) • Integration of open-source tools • Create alternative low-cost and collaborative model of scholarly publishing that is also portable • Technology transfer and human resource development (partnership with OSI, Electronic Publishing Trust for Development and others) International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Partners • CRIA – Centro de Referência em Informação Ambiental (Campanis, Brazil) www.cria.org.br (Reference Center for Environmental Information) Make scientific research useful and “useable” in a way that it can be incorporated in the definition of local, regional and national strategies for conservation and sustainable use of natural resources. Sidnei de Souza, Vanderlai Canhos, Dora Canhos International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Partners EPT, UK UT, Canada CRIA, Brazil International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br …Partners • Publishers from Africa (Kenya, Nigeria, South Africa, Uganda), Latin America (Brazil, Chile, Venezuela), India, Turkey and more… • University of Toronto Libraries • Department of Social Sciences, University of Toronto at Scarborough International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Collaboration provides • Shared resources and technology • Zero to very low start up cost • Tested technology • Acts as PubMedCentral for less developed countries • Cross-linking and hyper-linking • Advantage of established ranking and search positions ( Google Scholar, ISI Web of Content) • Full Integration with Eprints/T-Space server for long term archiving International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Operational aspects FILES GATHERED / NEW ISSUE PUBLISHED CREATED ARTICLE IMAGE CONVERSION CONVERSION FINAL TOUCHES & CHECKING FOR ACCURACY UPLOAD & CHECK EPrints & ARCHIVING International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Technical infrastructure Low cost hardware – Intel based computers Open Source / free software – Red Hat Linux OS – Perl – Javascript – PostgreSQL database – Apache Web Server • Standard Technologies – HTML, XML, XSLT, SQL, SOAP International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China PDF fullpaper OAI Harvester sspp220000 www.bioline.org.br OAI Harvester DSMZDSMZ PPDDFF FFuulll lP Paappeer r RReeppoossitiotoryry abstract fullpaper UT HTML PDFUT HTML DDooccuummeennt t FFuulll lP Paappeer r journals HTML Repository taggingtagging and and Repository foformrmaattinXMLttingg homepage SSppeeccieiess N Naammeess Database Database OAI Harvester AAbbsstrtaracctsts RReeppoossitiotoryry (XML) (XML) AAbbsstrtaracctsts DDaatatabbaassee OAI Harvester CCoonntrtorolelerr DDaatatabbaassee OAI Harvester XMLXML Config AAuuxx Files Files Config (XML/HTML) FFilieless (XML/HTML) International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China <article id="oc05011" lang="en" volume="100" number="01" month="02" year="2005“ pages="55-58" content="html" version="xml" received-date="20040319“ accepted-date="20041220" bioline-date="20050414" frewww.bioline.org.bre="yes"> <title lang="en">Antifungal activity from <taxon genus="Ocimum" species="gratissimum"><sp>Ocimum</sp> <sp>gratissimum</sp></taxon> L. towards <taxon genus="Cryptococcus" species="neoformans"><sp>Cryptococcus</sp> <sp>neoformans</sp></taxon> </title> <author>Janine de Aquino Lemos, Xisto Sena Passos, Orionalda de Fátima Lisboa Fernandes, José Realino de Paula, Pedro Henrique Ferri, Lúcia Kioko Hasimoto e Souza, Aline de Aquino Lemos, Maria do Rosário Rodrigues Silva </author> <keyword lang="en">Ocimum gratissimum, essential oil, eugenol, Cryptococcus neoformans</keyword> <abstract lang="en"> Cryptococcal infection had an increased incidence in last years due to the explosion of acquired immune deficiency syndrome epidemic and by using new and effective immunosuppressive agents. The currently antifungal therapies used such as amphotericin B, fluconazole, and itraconazole have certain limitations due to side effects and emergence of resistant strains. So, a permanent search to find new drugs for cryptococcosis treatment is essential. Ocimum gratissimum, plant known as alfavaca (Labiatae family), has been reported earlier with in vitro activity against some bacteria and dermatophytes. In our work, we study the in vitro activity of the ethanolic crude extract, ethyl acetate, hexane, and chloroformic fractions, essential oil, and eugenol of <i>O. gratissimum</i> using an agar dilution susceptibility method towards 25 isolates of <taxon genus="Cryptococcus" species="neoformans"><sp>Cryptococcus</sp> <sp>neoformans</sp></taxon>. All the extracts of <i>O. gratissimum</i> studied showed activity in vitro towards <i>C. neoformans</i>. Based on the minimal inhibitory concentration values the most significant results were obtained with chloroformic fraction and eugenol. It was observed that chloroformic fraction inhibited 23 isolates (92%) of <i>C. neoformans</i> at a concentration of 62.5 μg/ml and eugenol inhibited 4 isolates (16%) at a concentration of 0.9 μg/ml. This screening may be the basis for the study of <i>O. gratissimum</i> as a possible antifungal agent. </abstract> <copyright> Copyright 2005 - Instituto Oswaldo Cruz - Fiocruz. </copyright> </article> International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br Results of OA so far - conventional • Bioline journals included in numerous library e-journal & e- resource lists • Bioline E-Prints server included in ISI Current Web Contents - http://www.isinet.com/products/cap/ccc/cwc/ • Inclusion in Ulrich’s Serials Directory • Bioline journals listed in the Directory of Open Access Journals (DOAJ) – http://www.doaj.org • Featured in various articles: e.g. "Open Archives Initiative Data Providers. Part II: Science and Technology," Library Hi Tech News 21, no. 5 (June 2004): 22-30. 22-30. http://www.public.iastate.edu/~gerrymck/OAI-DP-II.pdf • Project recommended to journals by officials at the WHO International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China www.bioline.org.br International Conference on Strategies and Policies for Open Access to Scientific Information June 22-24, Beijing, China