Myozenin-2 Recombinant Protein Cat. No.: 92-145 Myozenin-2 Recombinant Protein Specifications SPECIES: Human SOURCE SPECIES: E. coli SEQUENCE: Met1-Leu264 FUSION TAG: C-6 His tag TESTED APPLICATIONS: APPLICATIONS: This recombinant protein can be used for biological assays. For research use only. PREDICTED MOLECULAR 30.9 kD WEIGHT: Properties Greater than 95% as determined by reducing SDS-PAGE. PURITY: Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. PHYSICAL STATE: Lyophilized Lyophilized from a 0.2 um filtered solution of 10mM Tris, pH 8.0. It is not recommended BUFFER: to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. September 24, 2021 1 https://www.prosci-inc.com/myozenin-2-recombinant-protein-92-145.html Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks. STORAGE CONDITIONS: Reconstituted protein solution can be stored at 4-7˚C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚C for 3 months. Additional Info OFFICIAL SYMBOL: MYOZ2 ALTERNATE NAMES: Myozenin-2, Calsarcin-1, FATZ-Related Protein 2, MYOZ2, C4orf5 ACCESSION NO.: Q9NPC6 PROTEIN GI NO.: 78070603 GENE ID: 51778 Background and References Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signaling. It may BACKGROUND: serve as intracellular binding proteins involved in linking Z line proteins such as alpha- actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signaling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 24, 2021 2 https://www.prosci-inc.com/myozenin-2-recombinant-protein-92-145.html.