Known Bioactive Library: Microsource Discovery 1 ICCB-L ICCB-L Vendor ID Compound Name Bioactivity Source TradeName References Cas # Plate Well Appl Microbiol Biotechnol 82:333 3264 A03 01506125 ALLYLTHIOUREA chelating agent synthetic 109-57-9 (2009) J Clin Endocrinol Metab 75:901 3264 A05 01506047 TIRATRICOL thyroid agent synthetic TRIAC 51-24-1 (1992) Toxicol Appl Pharmacol 14:515 synthetic; ENT- 3264 A07 01504191 PIPERONYL BUTOXIDE insecticide synergist BUTACIDE (1969); IARC Monographs 30:183 51-03-6 14250 (1983) 3264 A09 01506153 CARGLUMIC ACID carbamylphosphate synthetase activator synthetic CARBAGLU 1188-38-1 DIFLOXACIN synthetic; Abbott- Antimicrob Agents Chemother 29:193 3264 A11 01502359 antibacterial, DNA gyrase inhibitor DICURAL 91296-86-5 HYDROCHLORIDE 56619 (1986); 30:689 (1986 3264 A13 01506151 DEXFOSFOSERINE roborant synthetic 407-41-0 synthetic; ORF- Lancet 1:551 (1983); Int J Clin 3264 A15 01506200 THYMOPENTIN immunoregulator IMMUNOX 69558-55-0 15244 Pharmacol Res 4:431 (1984) 3264 A17 01506155 BENZOCLIDINE antihypertensive synthetic OXYLIDINE Pharmaceut Chem J 11:60 (1977) 16852-81-6 DARIFENACIN synthetic; UK- 3264 A19 01505714 M3 muscarinic antagonist, bladder suppressant ENABLEX 133099-07-7 HYDROBROMIDE 88525-04 3264 A21 01506158 MEPARFYLON hypnotic, sedative synthetic ALLOTROPAL Pharm J 2:184 (1976) 77-75-8 widely distributed in 3264 C03 01500987 GLUTAMINE (D) dietary suppliment NUTRESTORE 6899-04-3 plants J Clin Pharmacol Biopharm 17:475 3264 C05 01506173 NITROXOLINE antibacterial syntrhetic ENTEROCOL 4008-48-4 (1979); Pathol Biol 35:879 (1987) 3264 C07 01506108 TENYLIDONE contrast agent synthetic 893-01-6 vasoconstrictor, antihistamine, nasal 3264 C09 01506195 IPROHEPTINE synthetic METRON Arzneim Forsch 17:25 (1967) 13946-02-6 decongestant 3264 C11 01502383 ERDOSTEINE mucolytic synthetic; Rrv-144 SECRESOLV 84611-23-4 JACS 63:263 (1941); Science 3264 C13 01502345 URACIL antineoplastic synthetic; SQ-6201 66-22-8 133:1923 (1961) Contact Dermatitis 6:222 (1980); Acta 3264 C15 01506199 MEXENEONE sunscreen synthetic UVISTAT 1641-17-4 Derm Venereol 79:211 (1999) synthetic; HOE- Arch Int Pharmacodyn Ther 8:77 3264 C17 01502551 CHLOROBUTANOL antimicrobial CHLORETONE 57-15-8 095K (1901) Eur J Pharmacol 233:119 (1993); Biochem Biophys Res Commun PIMAGEDINE 3264 C19 01506176 glycosylation inhibitor synthetic; GER-11 199:147 (1994); 225:525 (1996) 1937-19-5 HYDROCHLORIDE PROFLAVINE 3264 C21 01504305 antiseptic synthetic; Brit J Exper Path 28:1 (1947) 553-30-0, 1811-28-5 HEMISULFATE 3264 E03 01506166 PICONOL decongestant synthetic 586-98-1 3264 E05 00307080 d-LIMONENE skin irritant, sensitizer Citrus oils, Helv Chim Acta 46:1480 (1963) 138-86-7 ESTRADIOL 3264 E07 01502400 estrogen semisynthetic J Clin Endocrinol 1:559 (1941) 113-38-2 DIPROPIONATE ANISODAMINE 3264 E09 00300047 anticholinergic, antispasmodic Scopolia tanguticus Naturwissenschaften 49: 281 (1962) 17659-49-3 HYDROBROMIDE citrus aurantium; 3264 E11 01506085 OXEDRINE anti-obesity 94-07-5 SYNEPHRINE 3264 E13 01301027 LACITOL laxative, sweetener synthetic IMPORTAL 585-86-4, 81025-04-9 Antimicrob Agents Chemother 19:82 3264 E15 01506107 SULFACARBAMIDE antibacterial synthetic SULFAUREA 547-44-4 (1981) 3264 E17 01506106 SULBENTINE antifungal synthetic; D-47 FUNGIPLEX Arch Pharm 293:957 (1960) 350-12-9 3264 E19 01506161 HEXYLENE GLYCOL humectant synthetic; PC-1 107-41-5 ADRENOLONE 3264 E21 01506124 adrenergic (opthalmic) synthetic STRYPHNASAL Int J Pharmaceut 1:189 (1978) 62-13-5, 99-45-6 (base) HYDROCHLORIDE Pharmacol Toxicol 74:244 3264 G03 01502356 LEVOSIMENDAN vasodilator synthetic; OR-1254 SIMDAX (1994);Cardiovasc Drud Rev 14:286 141505-33-1 (1996) MSDiscovery1 Page 1 of 10 Created 9/2015 ICCB-L ICCB-L Vendor ID Compound Name Bioactivity Source TradeName References Cas # Plate Well N-METHYL (-)EPHEDRINE 3264 G05 02300220 adrenergic agonist, analeptic synthetic 552-79-4 [1R,2S] synthetic; Bayer- 3264 G07 00330012 COUMOPHOS insecticide, cholinesterase inhibitor MELDANE 56-72-4 21199 3264 G09 01301025 ERYTHRITOL sweetener synthetic 149-32-6 J Chem Soc 1954:1171; 3264 G11 01505920 PANTETHINE antilipemic semisynthetic 16816-67-4 Atherosclerosis 50:73 (1984) 3264 G13 01502283 DIMESNA antineoplastic, uroprotectant synthetic 16208-51-8 analgesic, antiinflammatory, antipyretic, COX-II synthetic; ML- 3264 G15 01504526 FIROCOXIB EQIOXX Am J Vet Res 65:503 (2004) 189954-96-9 inhibitor 1785713 BETAMETHASONE 3264 G17 01505723 antiinflammatory semisynthetic CELESTOVET 987-24-6 ACETATE synthetic; BAY- Toxicol Appl Pharmacol 14:515 3264 G19 00330066 PROPOXUR insecticide BAYGON 114-26-1 39007, BAY-9010 (1969); Vet Med Rev 1:80 (1985) widespread in 3264 G21 01504524 ORNITHINE hepatoprotectant, anticholesteremic 70-26-8 nature synthetic; R- enatiomer of 3264 I03 01504283 ARMODAFINIL analeptic NUVIGIL 112111-43-0 modafinil (01505361) Eur J Biochem 229:558 3264 I05 01505167 ACADESINE glucose uptake stimulant; AMPK activator synthetic ARASINE (1995)Biochem J 338:783 (1999); J 2627-69-2 Mol Neurosci 17:45 (2001) 3264 I07 00212151 CHLORQUINALDOL antiinfectant, antifungal synthetic SITOSTERAN 72-80-0 meat extracts, sugar beet, Bacillus Biochem Biophys Res Commun subtilis, E. coli, 3264 I09 03100024 INOSINE cell function activator, cardiotonic 13:394 (1963); J Pharmacol 14:47 58-63-9 Saccharomyces (1983) cerevisiae, Fusarium spp 3264 I11 01505456 PARAMETHADIONE anticonvulsant synthetic PARADIONE 115-67-3 BETAMETHASONE 3264 I13 01505725 antiinflammatory, glucocorticoid semisynthetic CELESTONE 151-73-5 SODIUM PHOSPHATE semisynthetic; CL- J Econ Entomol 84:1266 (1991); Am J 3264 I15 01505394 MOXIDECTIN anthelmintic, antiparasitic CYDECTIN 113507-06-5 301423 Vet Res 53:1409 (1992) 3264 I17 01301017 AMYLENE HYDRATE hypnotic, antidiabetic, pharmaceutical aid synthetic Am J Med Sci 114:459 (1897) 75-85-4 ALISKIREN Curr Opin Invest Drugs 3:1479 3264 I19 01505710 renin inhibitor synthetic TEKTURNA 173334-57-1 HEMIFUMARATE (2002); Circulation 111:1012 (2005) synthetic; NSC- 3264 I21 01301014 CAPTAMINE depigmentor 108-02-1 45463 3264 K03 01301015 CYCLAMIC ACID sweetener synthetic HEXAMIC ACID 100-88-9 3264 K05 01301016 DEHYDROACETIC ACID antifungal, antibacterial synthetic DHA J Pharmacol Exp Ther 99:57 (1950) 520-45-6 RIBOFLAVIN 5- wdiespread in 3264 K07 01505763 vitamin, enzyme cofactor Helv Chim Acta 35:457 (1952) 130-40-5 PHOSPHATE SODIUM plants and animals synthetic; CGA- 3264 K09 01505903 CYROMAZINE acaricide, insecticide, ectoparisitide 66215-27-8 72662 Arzneim Forsch 2:165 (1952); 3:503 3264 K11 01505082 CYCLANDELATE vasodilator synthetic; BS-572 CYCLOSPASMOL 456-59-7 (1953) J Ocular Pharmacol Ther 17:421 3264 K13 01503871 TRAVOPROST antiglaucoma, PG-FP agonist synthetic; AL-6221 TRAVATAN 157283-68-6 (2001); Opthalmology 109:998 (2002) synthetic; BMS- 3264 K15 01502275 DASATINIB antineoplastic SPRYCEL 863127-77-9 354825-03 Med Res Rev 7: 29 (1987); Am J Trop semisynthetic; 3264 K17 01504143 ARTENIMOL antimalarial, antiinflammatory Med Hyg 61:187 (199); Trends 81496-81-3 dihydroartemisinin Pharmacol Sci 20:199 (1999) widespread in 3264 K19 01504525 OROTIC ACID hepatoprotectant, uricosuric agent J Biol Chem 202:91 (1953) 65-86-1 animals MSDiscovery1 Page 2 of 10 Created 9/2015 ICCB-L ICCB-L Vendor ID Compound Name Bioactivity Source TradeName References Cas # Plate Well J Chem Soc 1958: 2231; Org Biomol 3264 K21 01500819 BERGENIN hepatoprotectant Bergenia spp. 477-90-7 Chem. 6:2713 (2008) SODIUM TETRADECYL 3264 M03 01300042 sclerosing agent synthetic SOTRADECOL J Ind Hyg Toxicol 30:63 (1948) 139-88-8 SULFATE 52432-72-1, 468-61-1 3264 M05 01505774 OXELAIDIN CITRATE antitussive synthetic J Pharm Pharmacol 10:40 (1958) (base) CAMYLOFINE 3264 M07 01505785 anticholinergic synthetic 54-30-8 DIHYDROCHLORIDE 3264 M09 01504523 FTAXILIDE antiulcer synthetic; MP-12 19368-18-4 Arch Pathol Lab Med 100:127 (1976); 3264 M11 01504502 BITOSCANATE anthelmintic synthetic; 16842 JONIT 4044-65-9 J Pediatr Surg 18:131 (1983) 3264 M13 01503711 ORBIFLOXACIN antibacterial synthetic ORBAX 113617-63-3 synthetic; Chem Pharm Bull 25:1335 (1977; 3264 M15 01505762 PYRITINOL cognition enhancer, nootropic 1098-97-1 pyrithioxin Arzniem) Forsch 19:5 (1968) Cal West Med 37:405 (1932); J 3264 M17 01504510 CHINIOFON antiprotozoal, amebicide synthetic YATREN Pharmacol. Exper Ther 45:273 8002-90-2 (1932). 3264 M19 01504616 MEPIROXOL antihyperlipemic synthetic 6968-72-5 androgen, estrogen, treatment of menopausal adrenal glands, 3264 M21 01505083 PRASTERONE Lancet 343:1479 (1994) 53-43-0 syndrome male urine synthetic; 3264 O03 00330058 CHLORPYRIFOS insecticide 2921-88-2 DURSBAN 3264 O05 01504507 CHLORINDIONE antcoagulant, Vitamine K antagonist synthetic; G25766 1146-99-2 3264 O07 01504505 CARZENIDE diuretic, carbonic anhydrase inhibitor synthetic 138-41-0 3264 O09 01504518 EFLOXATE coronary vasodilator synthetic 119-41-5 1837-57-6; 6402-23-9 3264 O11 01505168 ETHACRIDINE LACTATE antiseptic, abortifaceant synthetic RIVANOL Clin Obster Gynacol 11:573 (1984) (hydrate) synthetic; J Pharmacol Exp Ther 229:851 hepatotoxic at 3264 O13 01504617 ISAXONINE nerve growth stimulant (1984); J Neurol Neurosurg Psychiatry 4214-72-6 clinical dose 48:933 (1985) (1500mg) 3264 O15 01504515 DIACETAMATE analgesic, antiinflammatory synthetic 2623-33-8 synthetic; FMC- Pestic Sci 6:537 (1975); 8:264 (1977); 3264 O17 01503606 CYPERMETHRIN insecticide BASATHRIN 52315-07-8 30980, PP-383 Arch Toxicol 67:510 (1993) HYDROXYPROGESTERON 3264 O19 01701060 progestin urine and blood 3168-01-2 E J AOAC 58:694 (1975); Anal Chem 3264 O21 01502316 NIFURSOL antiprotozoal