OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA323248 ACOX3 Rabbit Polyclonal Antibody Product data: Product Type: Primary Antibodies Applications: IHC Recommended Dilution: ELISA: 1:2000-5000, IHC: 1:50-200 Reactivity: Human, Mouse, Rat Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: Fusion protein corresponding to a region derived from 325-625 amino acids of human acyl- CoA oxidase 3, pristanoyl Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol Concentration: lot specific Purification: Antigen affinity purification Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Gene Name: acyl-CoA oxidase 3, pristanoyl Database Link: NP_003492 Entrez Gene 80911 MouseEntrez Gene 83522 RatEntrez Gene 8310 Human O15254 Background: Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. Synonyms: acyl-Coenzyme A oxidase 3; pristanoyl This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 ACOX3 Rabbit Polyclonal Antibody – TA323248 Protein Pathways: alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway Product images: Predicted cell location: Cytoplasm. Positive control: Human cervical and colon cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin- embedded human cervical cancer tissue using ACOX3 antibody at dilution 1/35, on the right is treated with the fusion protein. (Original magnification:x 200) Predicted cell location: Cytoplasm. Positive control: Human cervical and colon cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin- embedded human colon cancer tissue using ACOX3 antibody at dilution 1/35, on the right is treated with the fusion protein. (Original magnification:x200) This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2.