LEUKEMIA/MDS Other Leukemias of SPECIFIED CELL TYPE C94. Leukemia, C91. 0 - Acute erythroid leukemia LYMPHOID 2 - Acute megakaryoblastic leukemia 0 - Not having 3 - Mast cell leukemia achieved remission 0 - Acute lymphoblastic leukemia 4 - Acute panmyelosis with myelofibrosis 1 - In remission 1- Chronic lymphocytic leukemia of 8 - Other specified leukemias 2 - In relapse B-cell type 3 - Prolymphocytic leukemia of B-cell type 0 - Not having 6 - Myelodysplastic disease, not classified STOP 4 - Hairy cell leukemia achieved remission 5 - Adult T-cell lymphoma/leukemia 1 - In remission (HTLV-1-associated) 2 - In relapse 6 - Prolymphocytic leukemia of T-cell type Leukemia of A - Mature B-cell leukemia Burkitt-type C95. Z - Other lymphoid leukemia UNSPECIFIED 9 - Unspecified CELL TYPE 0 - Not having 0 - Acute achieved remission 1 - Chronic 1- In remission Leukemia, 9 - Unspecified C92. 2– In relapse MYELOID 0 - Acute myeloblastic leukemia Unspecified Malignant Neoplasms of 1 - Chronic myeloid leukemia, BCR/ABL- C96. positive 0 -Not having LYMPHOID, HEMATO 2 - Atypical chronic myeloid leukemia, achieved remission BCR/ABL-negative 1 - In remission POIETIC & RELATED TISSUE 3 - Myeloid sarcoma 2 - In relapse 0 - Multifocal and multisystemic (disseminated) 4 - Acute promyelocytic leukemia Langerhans-cell histiocytosis 5 - Acute myelomonocytic leukemia 2 - Malignant mast cell tumor 6 -Acute myeloid leukemia with 11q23- 4 - Sarcoma of dendritic cells (accessory cells) abnormality 5 - Multifocal and unisystemic Langerhans-cell A - Acute myeloid leukemia with histiocytosis multilineage dysplasia 6 - Unifocal Langerhans-cell histiocytosis Z - Other myeloid leukemia A - Histiocytic sarcoma 9 - Unspecified Z - Other specified 9 - Unspecified Leukemia, MONOCYTIC C93. MYELODYSPLASTIC D46. 0 - Acute monoblastic/monocytic SYNDROME (MDS) leukemia 0 - Not having achieved remission 0 - Refractory anemia without ring sideroblasts, so stated 1 - Chronic myelomonocytic leukemia 1 - Refractory anemia with ring sideroblasts 3 - Juvenile myelomonocytic leukemia 1- In remission 2– In relapse A - Refractory cytopenia with multilineage dysplasia Z - Other monocytic leukemia B - Refractory cytopenia with multilineage dysplasia and 9 - Unspecified ring sideroblasts C - Myelodysplastic syndrome with isolated del(5q) STOP chromosomal abnormality 4 - Refractory anemia, unspecified Z - Other myelodysplastic syndromes Poisoning by Adverse Effect of & Underdosing of, T45.1X 9 - Unspecified 0 - Not having achieved remission 2 - Refractory anemia ANTINEOPLASTIC & 1- 1 with excess of blasts IMMUNOSUPPRESSIVE DRUGS 2– 2 1- Poisoning by antineoplastic and Use T45.1X code for adverse effect, if applicable immunosuppressive drugs, A - initial encounter accidental (unintentional) D - subsequent encounter 5- Adverse effect of antineoplastic & S - sequela Multiple Myeloma & Malignant immunosuppressive drugs PLASMA CELL C90. NEOPLASM 0 - Multiple Myeloma 0 - Not having achieved remission 1 - Plasma cell leukemia 1 - In remission 2 - Extramedullary plasmacytoma 2 – In relapse 3 - Solitary plasmacytoma © Copyright 2015; Revised 9/24/15 HEMATOLOGY 1 B-CELL LYMPHOMA Lymphoma, Lymphoma, HODGKIN C81. OTHER C85. 0 - Nodular lymphocyte 0 - Unspecified site NON-HODGKIN predominant 1 - Head, neck, face 0 - Unspecified site 1 - Nodular sclerosis classical 2 - Intrathoracic 1 - Unspecified -B cell lymphoma 1 - Head, neck, face 2 - Mixed cellularity classical 3 - Intra-abdominal 2 - Mediastinal (thymic) large 2 - Intrathoracic 3 - Lymphocyte-depleted 4 - Axilla and upper limb B-cell 3 - Intra-abdominal classical 5 - Inguinal region and lower limb 8 - Other specified types of 4 - Axilla and upper limb 4 - Lymphocyte-rich classical 6 -Intrapelvic non-Hodgkin’s 5 - Inguinal region and lower limb 7 - Other classical 7 -Spleen 9 - Unspecified 6 -Intrapelvic 9 - Unspecified 8 - Multiple-sites 7 -Spleen 9 - Extranodal and solid organ site 8 - Multiple-sites 9 - Extranodal and solid organ site Lymphoma, Lymphomas C82. , FOLLICULAR MALIGNANT C88. 0 - Grade I 1 - Grade II 0 - Unspecified site IMMUNOPROLIFERATIVE 2 - Grade III unspecified 1 - Head, neck, face & OTHER B-CELLS 3 - Grade IIIa 2 - Intrathoracic 4 - Grade IIIb 3 - Intra-abdominal 0 - Waldenstrom macroglobulinemia 5 - Diffuse follicle center 4 - Axilla and upper limb 2 - Heavy chain disease lymphoma 5 - Inguinal region and lower limb 3 - Immunoproliferative small intestinal disease 6 - Cutaneous follicle center 6 -Intrapelvic 4 - Extranodal marginal zone B-cell lymphoma of mucosa- lymphoma 7 -Spleen associated lymphoid tissue MALT[ -lymphoma] 8 - Other types lymphoma 8 - Multiple-sites 8 - Other malignant immunoproliferative diseases 9 - Unspecified 9 - Extranodal and solid organ site 9 - Unspecified. Lymphoma, Other SPECIFIED T/NK-CELL C86. Lymphoma, 0 - Extranodal NK/T-cell lymphoma, nasal type C83. 1 - Hepatosplenic T-cell lymphoma NON-FOLLICULAR 2 - Enteropathy-type (intestinal) -T cell lymphoma 0 - Small cell B-cell Lymphoma 0 - Unspecified site 3 - Subcutaneous panniculitis-like-T-cell lymphoma 1 - Mantle cell Lymphoma 1 - Head, neck, face 4 - Blastic NK-cell lymphoma 3 - Diffuse Large -B cell 2 - Intrathoracic 5 - Angiommunoblastic -T cell lymphoma lymphoma 3 - Intra-abdominal 6 - Primary cutaneous CD-30-positive -T cell proliferations 5 - Lymphoblastic (diffuse 4 - Axilla and upper limb lymphoma) 5 - Inguinal region and lower limb 7 - Burkitt lymphoma 6 -Intrapelvic 8 - Other non-follicular 7 -Spleen Lymphoma (includes PEL/ 8 - Multiple-sites intravascular) 9 - Extranodal and solid organ site 9 - Unspecified © Copyright 2015; Revised 9/24/15 HEMATOLOGY 2 MYELOPROLIF/MGUS Neoplasms of Uncertain Behavior of POLYCYTHEMIA D45 LYMPHOID, HEMA- D47. VERA TOPOIETIC & RELATED TISSUE 0 - Histiocytic and mast cell tumors of uncertain behavior MONOCLONAL D47.2 1 - Chronic myeloproliferative disease GAMMOPATHY 2 - Monoclonal gammopathy STOP 3 - Essential (hemorrhagic) thrombocythemia 4 - Osteomyelofibrosis 9 - Unspecified Other & Unspecified Diseases of D75. Z - Other specified 1- Post-transplant lymphoproliferative BLOOD & BLOOD- neoplasms disorder (PTLD) 9 - Other specified neoplasms FORMING ORGANS For MYELOFIBROSIS, use D75.81 (MYELOFIBROSIS) 0 - Familial erythrocytosis 1 - Secondary polycythemia STOP ESSENTIAL D47.3 9 - Unspecified (HEMORRHAGIC) 8 - Other 1- MYELOFIBROSIS specified (Code first underlying disorder such as THROMBOCYTHEMIA diseases neoplasm. If applicable, code for associated of therapy-related MDS and for adverse effects blood and to identify drug) blood- 2 - Heparin induced thrombocytopenia (HIT) MYELOFIBROSIS D75.81 forming 9 - Other specified diseases of blood organs and blood-forming organs Anemia, NUTRITIONAL ANEMIAS FOLATE DEFICIENCY D52. Anemia, 0 –Dietary D50. 1 - Drug-induced IRON DEFICIENCY (Use additional code for adverse effects, 0 - Secondary to blood loss (chronic) if applicable, to identify drug) 1 - Sideropenic dysphagia 8 - Other 8 - Other iron deficiency anemias 9 - Unspecified 9 - Unspecified Anemias, Anemia, D53. D51. OTHER NUTRITIONAL VITAMIN B12 0 - Protein deficiency anemia 1 - Other megaloblastic anemias, DEFICIENCY not elsewhere classified 0 - Intrinsic factor deficiency 2 - Scorbutic anemia 1 - Selective vitamin B12 malabsorption with proteinuria 8 - Other 2 - Transcobalamin II deficiency 9 - Unspecified 3 - Other dietary Vitamin B12 deficiency 8 - Other 9 - Unspecified IRON OVERLOAD & E83.1 OTHERS 0 - Disorder of Iron Metabolism, unspecified STOP 0 - Hereditary 1 - Due to repeated red 1 - Hemochromatosis blood cell transfusions 8 - Other 9 - Unspecified © Copyright 2015; Revised 9/24/15 HEMATOLOGY Hemolytic Anemia, OTHER ANEMIAS ACQUIRED D59. 0 -Drug-induced autoimmune Anemia due to (Use additional code for adverse effects, if applicable, to D55. identify drug) ENZYME DISORDERS 1 - Other autoimmune 0 - Due to glucose-6-phosphate dehydrogenase [G6PD] deficiency 2 - Drug-induced non-autoimmune 1 - Other disorders of glutathione metabolism (Use additional code for adverse effects, if applicable, to 2 - Disorders of glycolytic enzymes identify drug) 3 - Disorders of nucleotide metabolism 3 - Hemolytic-uremic syndrome 8 - Other anemias (Use additional code to identify associated: E. coli, 9 - Unspecified Pneumoncoccal pneumonia, or Shigella dysenteriae) 4 - Other non-autoimmune 5 - Paroxysmal nocturnal hemoglobinuria (Marchiafava-Micheli) 6 - Hemoglobinuria due to hemolysis from other external causes 8 - Other acquired hemolytic anemias THALASSEMIA D56. 9 - Unspecified 0 –Alpha 1 - Beta 2 - Delta-beta 3 - Minor Other Aplastic Anemias & Other 4 - HPFH (Hereditary persistence of fetal hemoglobin) 5 - Hemoglobin E-beta D61. 8 - Other BONE MARROW 9 - Unspecified FAILURE SYNDROMES 0– Constitutional 1 - Constitutional (pure) red blood cell aplasia aplastic anemia 9 - Other constitutional aplastic anemia SICKLE CELL D57. 0 - Antineoplastic 8 - Other DISORDERS 1- Pancytopenia chemotherapy specified induced 0 - Unspecified aplastic pancytopenia 0 - Hb-SS with crisis 1 - Acute chest syndrome STOP anemias & 1 - Other drug-induced 2 - Splenic sequestration other bone pancytopenia marrow 8 - Other pancytopenia 1 - Sickle cell without crisis failure 2 - Myelophthisis 3 - Sickle-cell trait STOP syndromes 9- Other specified aplastic anemias STOP & other bone 2 - Hb-C disease 0 - Without crisis STOP 4 - Thalassemia marrow failure 8 - Other Sickle-Cell syndrome 1 - Acute chest 1 - With crisis syndrome 1 - Drug-induced aplastic anemia 2 - Splenic (If applicable, use additional code for adverse effects sequestration