Table of Contents Welcome Letter ...................................... 2 The Fairmont Hotel Scientifi c Advisory Board ......................... 3 Vancouver General Congress Information ................ 5 June 13 –16 Social Program ........................................5 2007 Program .................................................. 6 Invited Speaker Presentations ................15 Oral Abstracts ....................................... 36 Poster Presentation Listing .................... 58 Poster Abstracts .................................... 64 Exhibits ............................................... 123 Hotel Floorplan ................................... 124 Presenting Author Index ...................... 125 Satellite Symposia Schedule ................ 128 1 Welcome Message Dear Colleagues, It is with great pleasure we welcome you to the Fifth International Congress of Hair Research. The purpose of this conference is to bridge the basic scientist and clinician in their pursuit to help patients with hair diseases. This exchange of ideas usually has a major impact on the fi eld of trichologic medicine and helps determine directions of research. It stimulates interactions and development in the fi eld. Basic science and clinical topics will be showcased in the form of workshops, plenary lectures, satellite sessions and poster presentations. We have brought together a dynamic group of Invited Speakers for the pre-conference workshops and to provide invited lectures throughout the program. We would like to thank the Scientifi c Advisory Committee for their work in reviewing and selecting the abstract presentations for this program. And we are especially grateful to our corporate sponsors, without whom this congress would not have been possible. Vancouver is such a spectacular city and we hope that you will take full advantage of the beautiful sites, wonderful cuisine and diverse culture. The downtown core is surrounded by a natural harbour and majestic mountains and offers site-seeing, beaches, shipping, restaurants and Stanley Park – all within walking distance. We encourage you to set out on foot and enjoy the scenery. Jerry Shapiro, MD George Cotsarelis, MD Conference Chair NAHRS President 2 Scientifi c Advisory Board Conference Chair Europe Jerry Shapiro, MD Bruno Bernard, PhD University of British Columbia, Vancouver, BC, Canada L’Oreal, Clichy, France NAHRS President Ulrike Blume-Peytavi, MD Humboldt University of Berlin, Berlin, Germany George Cotsarelis, MD University of Pennsylvania, Philadelphia, PA, USA Francisco Camacho-Martinez, MD Avenida Republica Argentina, Seville, Spain North America Rolf Hoffman, MD Freiburg University, Freiburg, Germany Wilma Bergfeld, MD, PhD The Cleveland Clinic Foundation, Cleveland, OH, USA Andrew Messenger, MD Royal Hallamshire Hospital, Sheffi eld, United Kingdom Vladimir Botchkarev, MD, PhD Boston University School of Medicine, Boston, MA, USA Ralf Paus, MD University Hospital Eppendorf, University of Hamburg, Angela Christiano, PhD Hamburg, Germany Columbia University, New York, NY, USA Valerie Randall, PhD Cheng Ming Chuong, MD, PhD University of Bradford, West Yorkshire, United Kingdom University of Southern California, Los Angeles, CA, USA Antonella Tosti, MD Andrzej Dlugosz, MD University of Bologna, Bologna, Italy University of Michigan Medical School, Ann Arbor, MI, USA Ralph Trüeb, MD Maria Hordinsky, MD University Hospital Zurich, Zurich, Switzerland University of Minnesota, Minneapolis, MN, USA Dominique van Neste, MD Kevin McElwee, PhD Skinterface, Tournai, Belgium University of British Columbia, Vancouver, BC, Canada Sarah Millar, PhD Asia University of Pennsylvania, Philadelphia, PA, USA Seiji Arase, MD Elise Olsen, MD School of Medicine, University of Tokushima, Tokushima, Japan Duke University, Durham, NC, USA Satoshi Itami, MD, PhD Anthony Oro, MD, PhD Osaka University Graduate School of Medicine, Osaka, Japan Stanford University, Stanford, CA, USA Kensei Katsuoka, MD Vera Price, MD Kitasato University School of Medicine, Kanagawa, Japan University of California, San Francisco, CA, USA Byung In Ro, MD, PhD Janet Roberts, MD Myongji Hospital, Kwandong University College of Medicine, NAHRS, Portland, OR, USA Koyang, Kyunggi, Korea Hideoki Ogawa, MD, PhD Kurt Stenn, MD Juntendo University, School of Medicine, Tokyo Japan Aderans Research Institute, Philadelphia, PA, USA Ryoji Tsuboi, MD, PhD Ken Washenik, MD, PhD Tokyo Medical University, Tokyo, Japan Bosley Medical Group, Beverly Hills, CA, USA David Whiting, MD Australia Dallas Associated Dermatologists, Dallas, TX, USA Phlip Hynd, PhD University of Adelaide, Adelaide, SA, Australia Rodney Sinclair, MD University of Melbourne, Melbourne, Vic, Australia 3 4 General Congress Information Registration Desk Hours (BC Foyer): Program Session Codes Name badges must be worn at all times during the Scientifi c WS – Workshop O – Oral Abstract Program Sessions and Social Events. The registration desk S – Invited Speaker P – Poster Abstract staff would be pleased to answer any questions about Vancouver or the Congress. Session 4B: Animal and Human Pathology Tuesday, June 12 16:00 – 20:00 Thursday, June 14th, 15:30 to 17:00 Wednesday, June 13 07:30 – 20:00 Thursday, June 14 07:00 – 17:00 For those attending this session, the session speakers have arranged sample slides for viewing. Microscopes will be Friday, June 15 07:00 – 17:00 available beginning on Wednesday morning until the end Saturday, June 16 07:30 – 17:00 of the day. Please ask the Registration Desk staff for the location of the slide viewing. Speaker Services Centre (Tweedsmuir Room) Speakers are asked to bring a copy of the presentations on Poster Presentations a CD or memory stick in PC format to the Speaker Services Posters are located in the British Ballrom and will be Centre 24 hours prior to your presentation. Computers will available for viewing until Saturday noon. A poster session be available for revisions. will be held on Friday, June 15th from 15:00 to 17:30. Presenters will stand by their posters to answer questions Exhibit Area Hours (British Ballroom) during the following times: Thursday, June 14 10:00 – 17:00 15:30 – 16:30 Session 1: even numbered posters Friday, June 15 10:30 – 17:00 16:30 – 17:30 Session 2: odd numbered posters Saturday, June 16 09:30 – 12:30 Poster presenters are reminded to remove their posters from the British Ballroom by 13:00 hrs on Saturday, June Accreditation 16th. Congress Organizers cannot take responsibility for posters left in the room after this time. The North American Hair Research Society International Congress of Hair Research is recognized by the American Congress Language Academy of Dermatology for 26 Hours of AAD category 1 CME credit and may be used toward the American The offi cial language of the Congress is English. Academy of Dermatology‘s Continuing Medical Education Award. Message and Job Posting Board Will be available by the registration desk. Social Program Welcome Reception Evening Social Event: Reception-style Dinner at All Delegates and Registered Accompanying Persons are the Vancouver Aquarium and Science Centre invited to attend. All Delegates and Registered Accompanying Persons are Date: Wednesday, June 13th invited to attend. Time: 18:30 – 21:00 Date: Friday, June 15th Venue: The Roof, Fairmont Hotel Vancouver Time: 18:30 – 22:00 Dress: Business Casual Dress: Business Casual Join us for drinks and hors d’oeuvres. Mingle with friends Shuttle Service: Shuttle transfers to the Vancouver - old and new - a great way to begin the 5th International Aquarium will be available. Please Congress of Hair Research. meet in the hotel lobby for transfer service, beginning at 18:00. 5 Program Tuesday, June 12, 2007 Time Topic Speakers 16:00 – 20:00 Registration Open BC Foyer Wednesday, June 13, 2007 Time Session # Topic Speakers 07:30 – 20:00 Registration Open BC Foyer 08:00 – 12:00 AM Pre-Conference Workshops Co-chairs: Room: Pattern Hair Loss (PHL) Pre Conference Andrew Messenger, Vancouver Island Workshop 1 Satoshi Itami, Vera Price 08:00 – 08:20 WS-1-A Etiology of Pattern Hair Loss Andrew Messenger 08:20 – 08:40 WS-1-B Clinical Presentation, Workup FPHL Elise Olsen 08:40 – 08:55 WS-1-C Management of Male Pattern Hair Loss Dominique van Neste 08:55 – 09:05 WS-1-D Pathology of PHL Wilma Bergfeld 09:05 – 09:25 WS-1-E Pattern Hair Loss – Medical Therapy Jerry Shapiro 09:25 – 09:45 WS-1-F Surgical Management of Pattern Hair Loss Ken Washenik 09:45 – 10:00 WS-1-G In Search Of Therapies For Pattern Hair Loss: Satoshi Itami Defi ning The Challenges And Searching For Solutions 10:00 – 10:15 Questions 10:15 – 10:40 Refreshment Break 10:40 – 11:20 Patient Viewing 11:20 – 12:00 Patient Discussion Co-chairs: Room: Cicatricial Alopecia Pre-Conference Elise Olsen, Waddington Workshop 2 Rodney Sinclair, Ryoji Tsuboi 08:00 – 08:20 WS-2-A Classifi cation and Clinical Presentation Ralph Trüeb 08:20 – 08:30 WS-2-B Histopathology of Cicatricial Alopecia David Whiting 08:30 – 08:45 WS-2-C Etiology of Cicatricial Alopecia: Background and Kurt Stenn Hypotheses to Test 08:45 – 08:55 WS-2-D CD200 Attenuates Hair Follicle-specifi c Infl ammation Michael Rosenblum in Mice 08:55 – 09:15 WS-2-E PPAR Gamma Deletion in Stem Cells of the Pratima Karnik Hair Follicle Causes Scarring Alopecia 09:15 – 09:30 WS-2-F CCCA Update Elise Olsen 09:30 – 09:40 WS-2-G Secrets of Cicatricial Alopecias Revealed by Mouse John Sundberg Models 09:40 – 09:55 WS-2-H Cicatricial Alopecia: A Practical Diagnosis and Pascal Reygagne Therapeutic Approach 09:55 – 10:10