Children’s Hospital Los Angeles Annual Report 2017 About Us The mission of Children’s Hospital Los Angeles is to create hope and build healthier futures. Founded in 1901, CHLA is the top-ranked children’s hospital in California and among the top 10 in the nation, according to the prestigious U.S. News & World Report Honor Roll of children’s hospitals for 2017-18. The hospital is home to The Saban Research Institute and is one of the few freestanding pediatric hospitals where scientific inquiry is combined with clinical care devoted exclusively to children. Children’s Hospital Los Angeles is a premier teaching hospital and has been affiliated with the Keck School of Medicine of the University of Southern California since 1932. Table of Contents 2 4 6 8 A Message From the Year in Review Patient Care: Education: President and CEO ‘Unprecedented’ The Next Generation 10 12 14 16 Research: Legislative Action: Innovation: The Jimmy Figures of Speech Protecting the The CHLA Kimmel Effect Vulnerable Health Network 18 20 21 81 Donors Transforming Children’s Miracle CHLA Honor Roll Financial Summary Care: The Steven & Network Hospitals of Donors Alexandra Cohen Honor Roll of Friends Foundation 82 83 84 85 Statistical Report Community Board of Trustees Hospital Leadership Benefit Impact Annual Report 2017 | 1 This year, we continued to shine. 2 | A Message From the President and CEO A Message From the President and CEO Every year at Children’s Hospital Los Angeles is by turning attention to the hospital’s patients, and characterized by extraordinary enthusiasm directed leveraging our skills in the arena of national advocacy. toward the thoughtful improvement of the hospital’s care for children. This year, a few really unique things It is these instances—and those that do not get happened—and their results will undoubtedly make it a national attention but are simply all in a day’s work year that shapes the institution for decades to come. for our physicians, nurses and caregivers—that earn accolades from the likes of U.S. News & World Report, Children’s Hospital Los Angeles launched the CHLA which ranked CHLA the top hospital in California and Health Network—L.A.’s first clinically integrated sixth overall in the United States for 2017-2018. network for pediatricians. The organization was created to support and strengthen the practices of It is also our work to maintain vigorous and high- local pediatricians, provide them access to CHLA’s performing research initiatives to develop new specialty expertise and support their efforts to improve treatments and cures for pediatric patients, as well as the quality of clinical care for children. We proudly academic programs and compassionate care delivery launched the Network with more than 100 of the models that result in awards, national recognition and region’s finest pediatricians as affiliates. Interest in this honors in all categories. These are external symbols endeavor has been even greater than anticipated—the that affirm the life-changing work that literally occurs ranks of affiliated physicians continue to grow, and daily throughout the Children’s Hospital Los Angeles they are already working with CHLA to address health care continuum. the health care needs of children throughout all of Los Angeles County and beyond. I invite you to review this annual report to appreciate CHLA’s far-reaching impact. Outstanding years like Clinical program visibility is commonplace for CHLA 2017 inspire our faculty physicians, caregivers, thanks to our nationally renowned pediatric expertise volunteers, Trustees and donors with renewed combined with our family-centered, compassionate enthusiasm and hope for the future. care. However, this year, an unprompted, televised testimonial of gratitude coincided with a national We are grateful to each of you for your support of debate centered on health care coverage, giving CHLA CHLA. Please accept my thanks on behalf of all of the an opportunity to help politicians in Washington, D.C., children entrusted to our care. realize the impact of their decisions on children. Late- night talk-show host Jimmy Kimmel dedicated a widely Warmest regards, viewed monologue to thanking Children’s Hospital Los Angeles for the lifesaving heart surgery performed on his newborn son, and spoke to politicians, asking them to draft health care policy that gives all Paul S. Viviano children access to quality medical care. CHLA made President and Chief Executive Officer a significant contribution to the national dialogue Annual Report 2017 | 3 Year in Review James “Jim” E. Stein, MD, MSc, was named CHLA’s first senior vice president and chief medical officer. For the third time, the American The Make March Matter™ campaign, An accomplished surgeon and Nurses Credentialing Center supporting critical, lifesaving care leader, Stein served as the hospital’s bestowed Magnet recognition on for patients at Children’s Hospital chief medical quality officer and CHLA for demonstrating superior Los Angeles, raised more than associate chief for the Department of patient care, nursing excellence and $1.7 million in its second year. Surgery prior to this new role. professional innovation. More than 1,200 participants Robert E. Shaddy, MD, joined U.S. News & World Report ranked gathered to raise funds and show Children’s Hospital Los Angeles in CHLA the top pediatric medical their support for CHLA at the June as chair of the Department of center in California for 2017-18. inaugural Walk L.A. event in June Pediatrics, pediatrician in chief and CHLA was one of only 10 children’s 2017. The event raised $430,000 senior vice president of Academic hospitals named to the publication’s for the hospital. Affairs at CHLA, as well as chair prestigious Honor Roll and placed of Pediatrics at the Keck School sixth overall in the nation. of Medicine of the University of Southern California. Shaddy most recently served as the vice chair of the Department of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania, and chief of the Division of Cardiology at Children’s Hospital of Philadelphia. 4 | Year in Review Alexandra Carter, MBA, CFRE, joined CHLA as senior vice president and chief development officer in September, Robert C. Seeger, MD, was recently In March 2017, CHLA celebrated overseeing the hospital’s fundraising awarded an $11 million program its 50th year as a premier center efforts. Carter’s development project grant from the National for pediatric kidney transplantation, leadership has resulted in success for Cancer Institute of the National with the anniversary of the hospital’s a variety of nonprofit organizations, Institutes of Health, to study first kidney transplant in 1967. The including Cedars-Sinai Medical neuroblastoma as a model for high- hospital also performed its 300th Center and John Wayne Cancer risk cancer and the mechanisms it liver transplant in December 2016. Institute at Saint John’s Health Center. uses to evade treatment. CHLA joined in the March for An international team of hematologists More than 200 physicians with Science Los Angeles, held on including Guy Young, MD, of CHLA, privileges at CHLA were recognized April 22, 2017, in downtown found that in patients with hemophilia in Pasadena Magazine’s 10th annual Los Angeles to defend the vital A with inhibitors, a novel therapy Top Doctors issue for 2017. role of science in maintaining our called emicizumab decreases health, safety and economy. Diane incidence of bleeding episodes by Tanaka, MD, was a keynote speaker 87 percent. This treatment has been at the event. called the single most significant advancement in hemophilia medicine in the past 20 years. Annual Report 2017 | 5 PATIENT CARE ‘Unprecedented’ CAR-T therapy has been characterized as the single “We are using CAR-T therapy in children who have greatest therapeutic breakthrough in childhood exhausted all other treatment options,” says Wayne. leukemia in a generation—and Children’s Hospital “They are coming to us in dire straits. This therapy is Los Angeles has played a major role in its putting up to 90 percent of those children in remission, advancement. CHLA is one of only 32 hospitals in which is unprecedented.” the country approved to treat patients with this new therapy. The therapy involves taking a patient’s own white blood cells and genetically modifying them in the laboratory Alan Wayne, MD, and Michael Pulsipher, MD, helped so that they can recognize the patient’s leukemia and launched key clinical trials of the therapy—Wayne attack and kill the cancerous cells. Wayne says that in starting one of the first trials at the National Cancer the future, CAR-T therapy is expected to be used for Institute of the National Institutes of Health, and many other types of cancers as well. Pulsipher playing a leading role in organizing and completing the international trial leading to the U.S. “Beyond chemotherapy, radiation, surgery and bone Food and Drug Administration’s first approval of CAR-T marrow transplantation—we are now harnessing cells. Wayne is now head of the Children’s Center for the patient’s own immune system to attack their own Cancer and Blood Diseases at CHLA, and Pulsipher cancer. This is an extremely potent new tool in our war heads its Blood and Marrow Transplantation Section. on cancer.” 6 | ‘Unprecedented’ Annual Report 2017 | 7 “We are truly educating not just the next generation— but the current one.” - Ilanit Brook, MD 8 | The Next Generation EDUCATION The Next Generation Children’s Hospital Los Angeles launched two new pediatric gastroenterology. CHLA’s Liver Transplant pediatric medicine fellowships this year: one in Program is the largest in Southern California and its Pediatric Liver Transplant, and another in Hospice and fellowship program is in high demand, with the one- Palliative Medicine. Fellowships are advanced training year position already filled for 2018.