HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody Cat. No.: 59-972 HIST1H2BH/HIST1H2BK/HIST3H2BB Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human Predicted species reactivity based on immunogen sequence: Xenopus, Mouse, Bovine, HOMOLOGY: Chicken, Zebrafish, Rat This HIST1H2BH/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized IMMUNOGEN: with a KLH conjugated synthetic peptide between 26-52 amino acids from the Central region of human HIST1H2BH/HIST1H2BK/HIST3H2BB. TESTED APPLICATIONS: WB APPLICATIONS: For WB starting dilution is: 1:1000 PREDICTED MOLECULAR 14 kDa WEIGHT: Properties This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification. CLONALITY: Polyclonal September 26, 2021 1 https://www.prosci-inc.com/hist1h2bh-hist1h2bk-hist3h2bb-antibody-59-972.html ISOTYPE: Rabbit Ig CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide. CONCENTRATION: batch dependent Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Additional Info OFFICIAL SYMBOL: HIST1H2BH ALTERNATE NAMES: Histone H2B type 1-H, Histone H2Bj, H2B/j, HIST1H2BH, H2BFJ ACCESSION NO.: Q93079 PROTEIN GI NO.: 7387739 GENE ID: 8345 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with BACKGROUND: linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq]. REFERENCES: 1) Kim, S.C., et al. Mol. Cell 23(4):607-618(2006) 2) Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006) 3) Pavri, R., et al. Cell 125(4):703-717(2006) 4) Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006) ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 26, 2021 2 https://www.prosci-inc.com/hist1h2bh-hist1h2bk-hist3h2bb-antibody-59-972.html.