PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 8 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 8. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Utp20 Nop14 Wdr36 Tbl3 Utp14a Rps7 Utp14b Utp11l Utp20 Nop14 Wdr36 CEM 1 (242 datasets) Tbl3 Utp14a Rps7 Utp14b Singletons Utp11l Symbol Num ofCEMGenes:5.Predicted683.SelectedDatasets:242.Strength:1.8 CEM 1,Geneset"[G]small-subunitprocessome",Page1 Ebna1bp2 Mybbp1a Mrps18b Gemin5 Pdcd11 Ruvbl1 Atad3a Utp14a Polr1b Cirh1a Grwd1 Heatr1 Mak16 Nop16 Wdr46 Nop56 Wdr43 Nsun2 Wdr74 Wdr36 Nop14 Hspa4 Eif2b3 Ddx27 Ddx56 Ddx18 Rrp15 Rrp12 Pprc1 Utp20 Noc2l Noc4l Noc3l Nat10 Pwp2 Bop1 Nop2 Ppan Eif3b Ftsj3 Rrp9 Lyar Bysl Tsr1 Dis3 Gart Tbl3 Srm Aatf Nifk 0.0 1.0 GSE16874 [12] GSE6837 [8] GSE44175 [18] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE33942 [12] GSE20954 [14] GSE13693 [9] GSE38031 [8] GSE27092 [6] GSE20987 [12] GSE30160 [6] GSE15155 [12] GSE12498 [12] GSE38335 [9] GSE51483 [45] GSE13408 [14] GSE46606 [30] GSE27114 [6] GSE12499 [10] GSE26568 [6] GSE44923 [16] GSE46150 [8] GSE4535 [6] GSE53951 [10] GSE10273 [9] GSE17886 [16] GSE6957 [12] GSE34126 [19] GSE30745 [12] GSE39886 [24] GSE26096 [10] GSE32386 [13] GSE46185 [6] GSE16691 [12] GSE33156 [18] GSE46091 [8] GSE7069 [8] GSE7342 [12] GSE6526 [16] GSE15267 [8] GSE27605 [8] GSE8621 [12] GSE32598 [11] GSE18042 [18] GSE10912 [6] GSE32986 [18] GSE9878 [6] GSE5976 [12] GSE7012 [13] GSE46090 [12] GSE8091 [16] GSE21861 [8] GSE44261 [12] GSE10113 [12] GSE9735 [9] GSE21063 [24] GSE12948 [9] GSE40282 [6] GSE6689 [12] GSE51804 [10] GSE13692 [8] GSE48203 [9] GSE46942 [7] GSE12464 [23] GSE28389 [20] GSE38304 [8] GSE7764 [10] GSE48382 [10] GSE31166 [6] GSE25423 [10] GSE46724 [6] GSE6933 [15] GSE21491 [9] GSE18993 [13] GSE36814 [20] GSE18395 [8] GSE18660 [10] GSE31598 [12] GSE42047 [24] GSE33199 [64] GSE30855 [6] GSE20100 [15] GSE51243 [7] GSE32214 [6] GSE11220 [44] GSE44355 [10] GSE5671 [18] GSE27546 [51] GSE14012 [24] GSE49128 [17] GSE15173 [6] GSE34324 [12] GSE48935 [12] GSE42877 [14] GSE18135 [18] GSE34902 [6] GSE2527 [6] GSE11222 [42] GSE56777 [8] GSE17513 [12] GSE32277 [33] GSE7503 [6] GSE21670 [16] GSE20302 [12] GSE12581 [16] GSE10871 [32] GSE41895 [12] GSE39984 [18] GSE55809 [8] GSE39897 [36] GSE39034 [9] GSE30962 [16] GSE29632 [42] GSE27378 [8] GSE17316 [12] GSE42021 [27] GSE51883 [30] GSE21842 [8] GSE12465 [14] GSE13874 [14] GSE15268 [16] GSE10806 [11] GSE13547 [12] GSE13493 [6] GSE23006 [48] GSE15808 [29] GSE4189 [14] GSE48790 [8] GSE37000 [47] GSE28593 [9] GSE16454 [24] GSE42883 [12] GSE10246 [182] GSE10913 [6] GSE34723 [101] GSE34114 [12] GSE7897 [60] GSE10627 [51] GSE34618 [7] GSE20391 [11] GSE51608 [6] GSE24289 [6] GSE21033 [12] GSE27786 [20] GSE6085 [43] GSE27563 [93] GSE31406 [12] GSE25825 [8] GSE4739 [19] GSE21309 [9] GSE25645 [17] GSE37907 [24] GSE13590 [12] GSE6065 [100] GSE9954 [70] CEM+ CEM GSE18115 [8] GSE15610 [12] GSE9533 [35] GSE43197 [27] GSE18136 [12] GSE52075 [9] 0.0 GSE49248 [12] GSE47959 [8] GSE4288 [36] Scale ofaveragePearsoncorrelations GSE7759 [112] GSE37676 [6] GSE7050 [18] GSE6674 [15] GSE7460 [52] GSE15871 [18] 0.2 GSE29241 [6] GSE42135 [42] GSE34863 [8] GSE39458 [6] GSE14406 [54] GSE27159 [8] GSE56345 [9] GSE16679 [8] GSE13611 [8] 0.4 GSE15121 [6] GSE58262 [18] GSE22841 [12] GSE34961 [9] GSE48932 [12] GSE5332 [12] GSE34279 [30] GSE38001 [12] GSE20604 [6] 0.6 GSE9760 [12] GSE31570 [6] GSE7404 [144] GSE31028 [6] GSE22989 [10] GSE30868 [8] GSE23495 [6] GSE48397 [10] GSE30176 [12] 0.8 GSE46600 [44] GSE29929 [14] GSE46854 [20] GSE43419 [20] Score 205.97 207.00 208.24 209.93 210.30 212.24 212.63 213.00 214.55 214.60 214.88 215.48 215.61 216.13 217.67 218.68 219.99 220.33 223.06 223.74 226.02 226.38 227.05 227.43 227.67 233.73 233.87 235.00 237.62 238.02 241.15 241.30 241.39 241.52 244.09 246.38 246.80 247.30 247.65 248.62 251.48 256.17 258.02 261.11 264.20 1.0 Notes Mphosph10 Symbol Num ofCEMGenes:5.Predicted683.SelectedDatasets:242.Strength:1.8 CEM 1,Geneset"[G]small-subunitprocessome",Page2 Fam203a Tomm40 Gpatch4 Dnajc11 Exosc2 Rbm19 Smyd5 Rsl1d1 Prpf31 C1qbp Polr1e Polr1a Wdr55 Nop58 Ddx51 Abce1 Ddx21 Ddx39 Znhit6 Pa2g4 Prmt5 Gspt1 Trmt6 Abcf2 Utp15 Yars2 Bms1 Cct6a Nol11 Elac2 Wdr4 Nhp2 Nob1 Pno1 Pop1 Dkc1 Rcc1 Pus7 Pes1 Imp4 Urb2 Rars Rrs1 Gnl3 Adsl Nip7 Nle1 Ltv1 Ncl 0.0 1.0 GSE16874 [12] GSE6837 [8] GSE44175 [18] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE33942 [12] GSE20954 [14] GSE13693 [9] GSE38031 [8] GSE27092 [6] GSE20987 [12] GSE30160 [6] GSE15155 [12] GSE12498 [12] GSE38335 [9] GSE51483 [45] GSE13408 [14] GSE46606 [30] GSE27114 [6] GSE12499 [10] GSE26568 [6] GSE44923 [16] GSE46150 [8] GSE4535 [6] GSE53951 [10] GSE10273 [9] GSE17886 [16] GSE6957 [12] GSE34126 [19] GSE30745 [12] GSE39886 [24] GSE26096 [10] GSE32386 [13] GSE46185 [6] GSE16691 [12] GSE33156 [18] GSE46091 [8] GSE7069 [8] GSE7342 [12] GSE6526 [16] GSE15267 [8] GSE27605 [8] GSE8621 [12] GSE32598 [11] GSE18042 [18] GSE10912 [6] GSE32986 [18] GSE9878 [6] GSE5976 [12] GSE7012 [13] GSE46090 [12] GSE8091 [16] GSE21861 [8] GSE44261 [12] GSE10113 [12] GSE9735 [9] GSE21063 [24] GSE12948 [9] GSE40282 [6] GSE6689 [12] GSE51804 [10] GSE13692 [8] GSE48203 [9] GSE46942 [7] GSE12464 [23] GSE28389 [20] GSE38304 [8] GSE7764 [10] GSE48382 [10] GSE31166 [6] GSE25423 [10] GSE46724 [6] GSE6933 [15] GSE21491 [9] GSE18993 [13] GSE36814 [20] GSE18395 [8] GSE18660 [10] GSE31598 [12] GSE42047 [24] GSE33199 [64] GSE30855 [6] GSE20100 [15] GSE51243 [7] GSE32214 [6] GSE11220 [44] GSE44355 [10] GSE5671 [18] GSE27546 [51] GSE14012 [24] GSE49128 [17] GSE15173 [6] GSE34324 [12] GSE48935 [12] GSE42877 [14] GSE18135 [18] GSE34902 [6] GSE2527 [6] GSE11222 [42] GSE56777 [8] GSE17513 [12] GSE32277 [33] GSE7503 [6] GSE21670 [16] GSE20302 [12] GSE12581 [16] GSE10871 [32] GSE41895 [12] GSE39984 [18] GSE55809 [8] GSE39897 [36] GSE39034 [9] GSE30962 [16] GSE29632 [42] GSE27378 [8] GSE17316 [12] GSE42021 [27] GSE51883 [30] GSE21842 [8] GSE12465 [14] GSE13874 [14] GSE15268 [16] GSE10806 [11] GSE13547 [12] GSE13493 [6] GSE23006 [48] GSE15808 [29] GSE4189 [14] GSE48790 [8] GSE37000 [47] GSE28593 [9] GSE16454 [24] GSE42883 [12] GSE10246 [182] GSE10913 [6] GSE34723 [101] GSE34114 [12] GSE7897 [60] GSE10627 [51] GSE34618 [7] GSE20391 [11] GSE51608 [6] GSE24289 [6] GSE21033 [12] GSE27786 [20] GSE6085 [43] GSE27563 [93] GSE31406 [12] GSE25825 [8] GSE4739 [19] GSE21309 [9] GSE25645 [17] GSE37907 [24] GSE13590 [12] GSE6065 [100] GSE9954 [70] CEM+ CEM GSE18115 [8] GSE15610 [12] GSE9533 [35] GSE43197 [27] GSE18136 [12] GSE52075 [9] 0.0 GSE49248 [12] GSE47959 [8] GSE4288 [36] Scale ofaveragePearsoncorrelations GSE7759 [112] GSE37676 [6] GSE7050 [18] GSE6674 [15] GSE7460 [52] GSE15871 [18] 0.2 GSE29241 [6] GSE42135 [42] GSE34863 [8] GSE39458 [6] GSE14406 [54] GSE27159 [8] GSE56345 [9] GSE16679 [8] GSE13611 [8] 0.4 GSE15121 [6] GSE58262 [18] GSE22841 [12] GSE34961 [9] GSE48932 [12] GSE5332 [12] GSE34279 [30] GSE38001 [12] GSE20604 [6] 0.6 GSE9760 [12] GSE31570 [6] GSE7404 [144] GSE31028 [6] GSE22989 [10] GSE30868 [8] GSE23495 [6] GSE48397 [10] GSE30176 [12] 0.8 GSE46600 [44] GSE29929 [14] GSE46854 [20] GSE43419 [20] Score 177.31 178.18 178.87 178.95 179.09 179.09 179.39 179.70 181.19 181.24 181.48 181.90 182.00 182.45 184.44 184.97 185.49 186.24 186.96 187.33 188.01 188.26 188.29 189.22 189.68 190.00 190.26 192.32 192.49 192.69 192.88 194.30 194.31 194.54 194.64 195.39 196.47 197.57 197.67 198.35 199.54 200.70 201.40 201.81 202.66 202.68 203.96 204.88 205.02 205.63 1.0 Notes Symbol Num ofCEMGenes:5.Predicted683.SelectedDatasets:242.Strength:1.8 CEM 1,Geneset"[G]small-subunitprocessome",Page3 Zmynd19 Trmt61a Timm10 Sssca1 Mettl13 Dnttip2 Ruvbl2 Spata5 Mthfd1 Polr2h G3bp1 Heatr3 Wdr18 Aimp2 Bend3 Usp10 Apex1 Sdad1 Naa25 Naa15 Rrp1b Tex10 Gmps Dimt1 Nol10 Ptcd3 Sf3a3 Pwp1 Ttc27 Strap Gpn1 Wdr3 Nop9 Eif3g Eif3d Kti12 Xpo5 Pus1 Qtrt1 Lsg1 Rrp8 Gnl2 Utp6 Cct5 Ppat Tars Rcl1 Ipo5 Nkrf Atic 0.0 1.0 GSE16874 [12] GSE6837 [8] GSE44175 [18] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE33942 [12] GSE20954 [14] GSE13693 [9] GSE38031 [8] GSE27092 [6] GSE20987 [12] GSE30160 [6] GSE15155 [12] GSE12498 [12] GSE38335 [9] GSE51483 [45] GSE13408 [14] GSE46606 [30] GSE27114 [6] GSE12499 [10] GSE26568 [6] GSE44923 [16] GSE46150