LABORATORY CHEMICAL SAFETY REFERENCE MANUAL 2013 Risk Management Services www.riskmanagement.ubc.ca Table of Contents Emergency Contact Numbers ............................................................................................ 5 Forward and Disclaimer .................................................................................................... 6 University of British Columbia Safety Policy ........................................................................ 7 1. Introduction ................................................................................................................ 9 1.1 Risk Management Services (RMS) ............................................................................ 9 1.2 Duties and Responsibilities ...................................................................................... 9 1.3 Incident/Accident Reporting ..................................................................................... 9 1.4 Chemical Safety Program ....................................................................................... 10 1.5 Environmental Services Facility (ESF)...................................................................... 10 2. Risk Assessment ........................................................................................................ 11 2.1 Safe Experiment Design ......................................................................................... 11 2.1.1 Introduction ................................................................................................... 11 2.1.2 Responsibility ................................................................................................. 11 2.1.3 Procedure ...................................................................................................... 11 2.1.4 Sources of Information .................................................................................... 13 2.2 Workplace Hazardous Materials Information System (WHMIS) .................................. 14 2.2.1 Introduction ................................................................................................... 14 2.2.2 Background .................................................................................................... 14 2.2.3 Labels ............................................................................................................ 15 2.2.4 Material Safety Data Sheets ............................................................................. 18 2.3 Chemicals Hazards and Handling ............................................................................ 19 2.3.1 Introduction ................................................................................................... 19 2.3.2 Class A- Compressed Gases and Cryogenic Materials ......................................... 21 2.3.3 Class B- Flammable and Combustible Materials .................................................. 22 2.3.4 Class C- Oxidizing Materials ............................................................................. 24 2.3.5 Class D- Toxic Material .................................................................................... 25 2.3.6 Class E- Corrosive Materials ............................................................................ 30 2.3.7 Class F- Dangerously Reactive Materials ............................................................ 31 2.3.8 Special Hazardous Chemicals ........................................................................... 33 3. Risk Control ............................................................................................................... 35 3.1 Introduction ......................................................................................................... 35 3.2 Engineering Controls ............................................................................................. 35 Revision of: 2011 page 2 of 100 Revised By: Richard Colwell Risk Management Services Chemical Laboratory Safety Manual.doc 3.2.1 Facilities & Equipment ..................................................................................... 35 3.2.2 Laboratory Fume Hoods .................................................................................. 36 3.2.3 Safety Showers and Eye Wash Stations ............................................................. 37 3.2.4 Refrigerators .................................................................................................. 38 3.2.5 Temperature Control ....................................................................................... 38 3.2.6 Control of Suck-Back ....................................................................................... 39 3.2.7 Reduced Pressure Operations........................................................................... 39 3.2.8 Centrifuge Safety ............................................................................................ 39 3.2.9 Electrophoresis apparatus ................................................................................ 40 3.2.10 Lyophilizer Safety .......................................................................................... 40 3.3 Administrative Controls ......................................................................................... 41 3.3.1 Chemical Storage and Segregation ................................................................... 41 3.3.1.1 Inventory ................................................................................................ 41 3.3.1.2 General Rules for Safe Storage ................................................................... 43 3.3.1.3 Chemical Segregation for Storage ............................................................... 43 3.3.1.4 Storage Guidelines of Specific Hazard Classes .............................................. 45 3.3.2 WHMIS Worker Education and Training ............................................................ 47 3.3.3. Laboratory Inspections ................................................................................... 47 3.3.4 Fire Safety Procedures ..................................................................................... 50 3.3.5 Treatment of Injuries ...................................................................................... 50 3.3.6 Spill Clean-Up Procedures ................................................................................ 50 3.4 Personal Protective Equipment ............................................................................... 52 3.4.1 Protective Clothing .......................................................................................... 52 3.4.2 Respitory Protection ........................................................................................ 55 3.4.3 Eye or Face Protection ..................................................................................... 55 3.4.4 Hearing Protection .......................................................................................... 56 3.5 Occupational and Preventive Health Program .......................................................... 56 4. Waste Disposal ......................................................................................................... 58 5. Transportation and Receiving of Hazardous Materials on Campus................................... 60 5.1 Certification .......................................................................................................... 60 5.2 Receiving Procedures ............................................................................................ 60 5.3 Dangerous Goods Hazard Categories ...................................................................... 60 5.4 Shipping Description ............................................................................................. 61 5.5 Safety Symbols and Labels .................................................................................... 62 5.6 Documentation Required ....................................................................................... 62 5.7 Dangerous Occurrences ......................................................................................... 63 5.8 Packaging Damaged in Transport ........................................................................... 63 6. References ................................................................................................................ 64 Revision of: 2011 page 3 of 100 Revised By: Richard Colwell Risk Management Services Chemical Laboratory Safety Manual.doc Appendix A: Handwashing Procedure for Laboratories ...................................................... 64 Appendix B: General Laboratory Safety Rules ................................................................... 65 Work Habits ............................................................................................................... 65 Safety Wear ............................................................................................................... 65 Purchasing, Use and Disposal ...................................................................................... 65 Substitutions .............................................................................................................. 66 Appendix C: Flash Points of Common Flammable Liquids ................................................... 67 Appendix D: Carcinogens, Reproductive Toxins and Sensitizers .......................................... 70 Appendix E: Dangerously Reactive Materials (from TDG List) ............................................