LIG1 Antibody Cat. No.: 26-847 LIG1 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human LIG1. TESTED APPLICATIONS: ELISA, WB LIG1 antibody can be used for detection of LIG1 by ELISA at 1:62500. LIG1 antibody can be APPLICATIONS: used for detection of LIG1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. POSITIVE CONTROL: 1) 721_B Cell Lysate PREDICTED MOLECULAR 102 kDa WEIGHT: Properties PURIFICATION: Antibody is purified by peptide affinity chromatography method. CLONALITY: Polyclonal CONJUGATE: Unconjugated PHYSICAL STATE: Liquid September 29, 2021 1 https://www.prosci-inc.com/lig1-antibody-26-847.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose. CONCENTRATION: batch dependent For short periods of storage (days) store at 4˚C. For longer periods of storage, store LIG1 STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. Additional Info OFFICIAL SYMBOL: LIG1 ALTERNATE NAMES: LIG1, MGC117397, MGC130025, ACCESSION NO.: NP_000225 PROTEIN GI NO.: 4557719 GENE ID: 3978 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References LIG1is DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that BACKGROUND: lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. REFERENCES: 1) Liang, L., (2008) Nucleic Acids Res. 36 (10), 3297-3310. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 29, 2021 2 https://www.prosci-inc.com/lig1-antibody-26-847.html.