CLH REPORT FOR POTASSIUM CHLORATE CLH report Proposal for Harmonised Classification and Labelling Based on Regulation (EC) No 1272/2008 (CLP Regulation), Annex VI, Part 2 International Chemical Identification: Potassium chlorate EC Number: 223-289-7 CAS Number: 3811-04-9 Index Number: 017-004-00-3 Contact details for dossier submitter: Swedish Chemicals Agency Esplanaden 3a, P.O Box 2 SE-172 13 Sundbyberg, Sweden [email protected] +46 8 519 41 100 Version number: 5 Date: 03/04/2020 CLH REPORT FOR POTASSIUM CHLORATE CONTENTS 1 IDENTITY OF THE SUBSTANCE........................................................................................................................1 1.1 NAME AND OTHER IDENTIFIERS OF THE SUBSTANCE...............................................................................................1 1.2 COMPOSITION OF THE SUBSTANCE..........................................................................................................................1 2 PROPOSED HARMONISED CLASSIFICATION AND LABELLING............................................................3 2.1 PROPOSED HARMONISED CLASSIFICATION AND LABELLING ACCORDING TO THE CLP CRITERIA............................3 3 HISTORY OF THE PREVIOUS CLASSIFICATION AND LABELLING ......................................................5 4 JUSTIFICATION THAT ACTION IS NEEDED AT COMMUNITY LEVEL.................................................5 5 IDENTIFIED USES..................................................................................................................................................5 6 DATA SOURCES .....................................................................................................................................................6 7 PHYSICOCHEMICAL PROPERTIES .................................................................................................................6 8 EVALUATION OF PHYSICAL HAZARDS.........................................................................................................9 9 TOXICOKINETICS (ABSORPTION, METABOLISM, DISTRIBUTION AND ELIMINATION) ..............9 10 EVALUATION OF HEALTH HAZARDS ............................................................................................................9 ACUTE TOXICITY ..............................................................................................................................................................9 10.1 ACUTE TOXICITY - ORAL ROUTE.........................................................................................................................9 10.1.1 Short summary and overall relevance of the provided information on acute oral toxicity...................14 10.1.2 Comparison with the CLP criteria ........................................................................................................17 10.1.3 Conclusion on classification and labelling for acute oral toxicity........................................................18 10.2 ACUTE TOXICITY - DERMAL ROUTE..................................................................................................................18 10.3 ACUTE TOXICITY - INHALATION ROUTE ...........................................................................................................18 10.3.1 Short summary and overall relevance of the provided information on acute inhalation toxicity .........19 10.3.2 Comparison with the CLP criteria ........................................................................................................19 10.3.3 Conclusion on classification and labelling for acute inhalation toxicity..............................................19 10.4 SKIN CORROSION/IRRITATION ..........................................................................................................................20 10.5 SERIOUS EYE DAMAGE/EYE IRRITATION...........................................................................................................20 10.6 RESPIRATORY SENSITISATION ..........................................................................................................................20 10.7 SKIN SENSITISATION.........................................................................................................................................20 10.8 GERM CELL MUTAGENICITY.............................................................................................................................20 10.9 CARCINOGENICITY...........................................................................................................................................20 10.10 REPRODUCTIVE TOXICITY ................................................................................................................................20 10.11 SPECIFIC TARGET ORGAN TOXICITY-SINGLE EXPOSURE ...................................................................................20 10.12 SPECIFIC TARGET ORGAN TOXICITY-REPEATED EXPOSURE ..............................................................................20 10.13 ASPIRATION HAZARD .......................................................................................................................................20 11 EVALUATION OF ENVIRONMENTAL HAZARDS.......................................................................................20 11.1 RAPID DEGRADABILITY OF ORGANIC SUBSTANCES ..........................................................................................21 11.2 ENVIRONMENTAL TRANSFORMATION OF METALS OR INORGANIC METALS COMPOUNDS .................................21 11.3 ENVIRONMENTAL FATE AND OTHER RELEVANT INFORMATION........................................................................22 11.3.1 Ready biodegradability..........................................................................................................................22 11.3.2 Hydrolysis..............................................................................................................................................23 11.3.3 Other convincing scientific evidence.....................................................................................................24 11.4 BIOACCUMULATION.........................................................................................................................................24 11.5 ACUTE AQUATIC HAZARD ................................................................................................................................24 11.5.1 Acute (short-term) toxicity to fish..........................................................................................................25 11.5.2 Acute (short-term) toxicity to aquatic invertebrates..............................................................................25 11.5.3 Acute (short-term) toxicity to algae or other aquatic plants .................................................................26 11.5.4 Acute (short-term) toxicity to other aquatic organisms.........................................................................28 11.6 LONG-TERM AQUATIC HAZARD........................................................................................................................29 11.6.1 Chronic toxicity to fish...........................................................................................................................29 11.6.2 Chronic toxicity to aquatic invertebrates ..............................................................................................30 CLH REPORT FOR POTASSIUM CHLORATE 11.6.3 Chronic toxicity to algae or other aquatic plants..................................................................................30 11.6.4 Chronic toxicity to other aquatic organisms .........................................................................................33 11.7 COMPARISON WITH THE CLP CRITERIA............................................................................................................33 11.7.1 Acute aquatic hazard .............................................................................................................................33 11.7.2 Long-term aquatic hazard (including bioaccumulation potential and degradation)............................34 11.8 CONCLUSION ON CLASSIFICATION AND LABELLING FOR ENVIRONMENTAL HAZARDS.......35 12 EVALUATION OF ADDITIONAL HAZARDS .................................................................................................35 13 ADDITIONAL LABELLING................................................................................................................................35 14 REFERENCES........................................................................................................................................................36 CLH REPORT FOR POTASSIUM CHLORATE 1 IDENTITY OF THE SUBSTANCE 1.1 Name and other identifiers of the substance Table 1: Substance identity and information related to molecular and structural formula of the substance Name(s) in the IUPAC nomenclature or other Potassium chlorate international chemical name(s) Other names (usual name, trade name, abbreviation) / ISO common name (if available and appropriate) / EC number (if available and appropriate) 223-289-7 EC name (if available and appropriate) Potassium chlorate CAS number (if available) 3811-04-9 Other identity code (if available) / Molecular formula ClHO3.K Structural formula SMILES notation (if available) [K+].[O-]Cl(=O)=O Molecular weight or molecular weight range 122.5495 g/mol Information on optical activity and typical ratio of Not applicable