CERTIFICATION EXAMINATION IN CHILD NEUROLOGY 2016 Content Blueprint (October 27, 2015) Part A Basic neuroscience Number of questions: 120 01. Neuroanatomy 3-5% 02. Neuropathology 3-5% 03. Neurochemistry 2-4% 04. Neurophysiology 5-7% 05. Neuroimmunology/neuroinfectious disease 2-4% 06. Neurogenetics/molecular neurology, neuroepidemiology 2-4% 07. Neuroendocrinology 1-2% 08. Neuropharmacology 4-6% Part B Behavioral neurology, cognition, and psychiatry Number of questions: 80 01. Development through the life cycle 3-5% 02. Psychiatric and psychological principles 1-3% 03. Diagnostic procedures 1-3% 04. Clinical and therapeutic aspects of psychiatric disorders 5-7% 05. Clinical and therapeutic aspects of behavioral neurology 5-7% Part C Clinical neurology (adult and child) The clinical neurology section of the Child Neurology Certification Examination is comprised of 70% child neurology questions and 30% adult neurology questions. Number of questions: 200 01. Headache disorders 1-3% 02. Pain disorders 1-3% 03. Epilepsy and episodic disorders 1-3% 04. Sleep disorders 1-3% 05. Genetic disorders 1-3% 06. Congenital disorders 1-3% 07. Cerebrovascular disease 1-3% 08. Neuromuscular diseases 2-4% 09. Cranial nerve palsies 1-3% 10. Spinal cord diseases 1-3% 2016 ABPN Content Specifications Page 1 of 19 Posted: November 12, 2015 Certification in Child Neurology 11. Movement disorders 1-3% 12. Demyelinating diseases 1-3% 13. Neuroinfectious diseases 1-3% 14. Critical care 1-3% 15. Trauma 1-3% 16. Neuro-ophthalmology 1-3% 17. Neuro-otology 1-3% 18. Neurologic complications of systemic diseases 2-4% 19. Neuro-oncology 1-3% 20. Neurotoxicology 1-3% 21. Pregnancy and neurology 1-3% 22. Child neurology specific disorders 2-4% 23. Ethics 1-3% 24. Clinical diagnostic and therapeutic procedures 2-4% 25. Interpersonal and communication skills 1-3% 26. Systems-based practice issues 1-3% TOTAL 100% CERTIFICATION EXAMINATION IN NEUROLOGY 2016 Content Outline Part A Basic neuroscience 01. Neuroanatomy A. Cerebral cortex B. Connecting systems C. Basal ganglia/thalamus D. Brainstem E. Cerebellum F. Cranial nerves G. Spinal cord H. Spinal roots/peripheral nerves I. Ventricular system, CSF J. Vascular K. Neuromuscular junction/muscle L. Autonomic nervous system 2016 ABPN Content Specifications Page 2 of 19 Posted: November 12, 2015 Certification in Child Neurology M. Embryology and neural development N. Pain pathways O. Radiologic anatomy, cerebral blood vessels (angiography or MRA) P. CSF anatomy, physiology, normal and abnormal patterns (cellular, chemical, enzymatic, serologic) Q. Other 02. Neuropathology A. Basic patterns of reaction B. Cerebrovascular disease C. Trauma (cranial and spinal) D. Metabolic/toxic/nutritional diseases E. Infections F. Demyelinating diseases/leukodystrophies G. Neoplasms H. Congenital/developmental anomalies I. Degenerative/heredodegenerative disorders J. Myopathies K. Peripheral nerve L. Neuromuscular junction disorders M. Radiologic pathology pertinent to assigned pathology sections N. Other 03. Neurochemistry A. Carbohydrate metabolism B. Lipid metabolism C. Protein metabolism D. Neurotransmitters E. Axonal transport F. Energy metabolism G. Blood-brain barrier H. Biochemistry of membranes/receptors/ion channels I. Neuronal excitation J. Vitamins (general aspects) K. Inborn errors of metabolism L. Electrolytes and minerals M. Neurotoxins N. Free radical scavengers O. Excitotoxicity P. Normal CSF constituents and volume Q. Other 04. Neurophysiology 2016 ABPN Content Specifications Page 3 of 19 Posted: November 12, 2015 Certification in Child Neurology A. Membrane physiology B. Synaptic transmission C. Sensory receptors and perception D. Special senses E. Reflexes F. Segmental and suprasegmental control of movement G. Cerebellar function H. Reticular system: mechanisms of sleep and arousal, consciousness, circadian rhythms I. Rhinencephalon; limbic system; visceral brain J. Learning and memory K. Cortical organization and function L. Pathophysiology of epilepsy M. Cerebral blood flow N. Autonomic function O. Blood-brain barrier P. Neurophysiology of the visual system Q. Neurophysiology of hearing and vestibular function R. Physiology of pain S. Physiology of peripheral nerve and muscle T. Other 05. Neuroimmunology/neuroinfectious disease A. Molecular pathogenesis of multiple sclerosis B. Molecular neurology of prion and infectious diseases C. Immunotherapy in multiple sclerosis, myasthenia gravis, and other neurologic disorders D. Other 06. Neurogenetics/molecular neurology, and neuroepidemiology A. Mendelian-inherited diseases B. Other modes of inheritance C. Mitochondrial disorders D. Trinucleotide repeat disorders E. Channelopathies F. Genetics of epilepsy G. Risk factors in neurologic disease H. Demographics of neurologic disease 07. Neuroendocrinology A. Thyroid gland B. Cushing syndrome C. Corticosteroids 2016 ABPN Content Specifications Page 4 of 19 Posted: November 12, 2015 Certification in Child Neurology D. Growth hormones E. Hypothalamic function F. Adrenal gland G. Pituitary gland H. Prolactin I. Androgen 08. Neuropharmacology A. General principles of neuropharmacology 1. Neuropharmacokinetics/ neuropharmacodynamics 2. Drug interactions 3. Age, gender, and ethnicity issues B. Anti-seizure medications C. Antibiotics/antimicrobials/vaccines D. Neuromuscular agents (neuromuscular junction) E. Therapeutic agents in movement disorders F. Vitamins (clinical aspects) 1. Vitamin deficiency states a. Vitamin B6 (pyridoxine) deficiency and dependency b. Vitamin B1 (thiamine) deficiency c. Vitamin B₁₂ (cobalamin) deficiency d. Nicotinic acid deficiency (pellagra) e. Biotinidase 2. Vitamin excess a. Hypervitaminosis A b. Hypervitaminosis D c. Vitamin B6 (pyridoxine) excess administration G. Analgesics (non-narcotics, narcotics, and other centrally active agents) H. Anticoagulants, antiplatelets, and thrombolytic agents I. Hormones J. Immunomodulatory and immunosuppressive agents K. Anticholinesterase drugs L. Neurologic side effects of systemic drugs M. Drugs used in cognitive disorders N. Miscellaneous drugs 2016 ABPN Content Specifications Page 5 of 19 Posted: November 12, 2015 Certification in Child Neurology Part B Behavioral neurology, cognition, and psychiatry 01. Development through the life cycle A. Infancy through adolescence, including developmental processes, tasks, crises, and transitions (e.g., school entry, peer relations, individuation) B. Adulthood, including developmental processes, tasks, crises, transitions (e.g., employment, parenting), and acquisition/loss of specific capacities (e.g., menopause) C. Late life, including developmental processes, tasks, crises, transitions, and acquisition/loss of specific capacities (e.g., cognition, physical endurance) 02. Psychiatric and psychological principles A. Cognition, including neuropsychology and cognitive psychology B. Psychological defenses 03. Diagnostic procedures A. Mental status examination B. Cognitive and neuropsychological testing 04. Clinical and therapeutic aspects of psychiatric disorders A. Disorders associated with infancy, childhood, or adolescence 1. Mental retardation (DSM-IV)/intellectual disability (DSM-5) 2. Learning disorders 3. Motor skills disorder 4. Communication disorders 5. Pervasive developmental disorders (DSM-IV)/autism spectrum disorders (DSM-5) 6. Attention-deficit and disruptive behavior disorders 7. Tic disorders 8. Elimination disorders 9. Other B. Schizophrenia and other psychotic disorders 1. Schizophrenia, schizophreniform and schizoaffective disorders 2. Brief psychotic disorder 3. Psychotic disorder due to a general medical condition (DSM- IV)/psychotic disorder due to another medical condition (DSM-5) 4. Substance-induced psychotic disorder (DSM- IV)/substance/medication-induced psychotic disorder (DSM-5) 5. Other C. Mood disorders (DSM-IV)/depressive disorders and bipolar and related disorders (DSM-5) 1. Depressive disorders a. Major depressive disorder b. Dysthymic disorder (DSM-IV)/persistent depressive disorder 2016 ABPN Content Specifications Page 6 of 19 Posted: November 12, 2015 Certification in Child Neurology [dysthymia] (DSM-5) c. Mood disorder due to a general medical condition (DSM- IV)/depressive disorder due to another medical condition (DSM-5) d. Other depressive disorders 2. Bipolar disorders a. Bipolar I disorder b. Bipolar II disorder 3. Other D. Anxiety disorders and obsessive-compulsive and related disorders 1. Panic disorder 2. Obsessive-compulsive disorder 3. Posttraumatic stress disorder 4. Acute stress disorder 5. Generalized anxiety disorder 6. Anxiety disorder due to a general medical condition (DSM-IV)/anxiety disorder due to another medical condition (DSM-5) 7. Substance-induced anxiety disorder (DSM-IV)/ substance/medication- induced anxiety disorder (DSM-5) 8. Other E. Somatoform disorders (DSM-IV)/somatic symptom and related disorders (DSM- 5) 1. Conversion disorder 2. Hypochondriasis (DSM-IV)/somatic symptom disorder (DSM-5) or illness anxiety disorder (DSM-5) 3. Other F. Factitious disorders G. Dissociative disorders 1. Dissociative amnesia 2. Other H. Personality disorders 1. Cluster A 2. Cluster B 3. Cluster C I. Eating disorders (DSM-IV)/feeding and eating disorders (DSM-5) 1. Anorexia nervosa 2. Bulimia nervosa J. Adjustment disorders (DSM-IV)/trauma- and stressor-related disorders (DSM-5) K. Treatment of psychiatric disorders 1. General principles of psychopharmacology 2016 ABPN Content Specifications Page 7 of 19 Posted: November 12, 2015 Certification in Child Neurology a.