Supporting Materials A New Wave in Integrative Medicine: Ayurvedic Medicine for the Modern Practitioner Stuart Rothenberg, M.D. Nancy Lonsdorf, M.D. National Co-Directors, Institute of Integrative Ayurveda Medical Education Maharishi Ayur-Veda Health Professionals Training Program Level One, Module 1 The Ayurvedic Classical Texts The Charaka Samhita Brihat Trayi: Sushruta Samhita Ashtanga Hridaya Samhita (Vagbhata Samhita) the 3 major texts The Bhava-Prakash Samhita Laghu Trayi: Sharngadhar Samhita Madhav Nidan Samhita the 3 minor texts Other Kashyap Samhita Classical Texts Bhel Samhita Harita Samhita “Good health stands at the very root of virtuous acts, acquirement of wealth, fulfillment of desires, and ultimate emancipation. Diseases are destroyers of health, well-being, and life. This has manifested itself as a great obstacle in the way of human life. What could be its remedy? With this end in view, they (the sages) entered into meditation…” -Charaka Samhita, Sutrasthana 1.15-16 Copyright 2014, Maharishi Ayur-Veda Association of America 2.8 Maharishi Ayur-Veda Health Professionals Training Program Level One, Module 1 12. Correlation with Modern Physics: Unified Field Theory (super-symmetric superstring theory) Copyright 2014, Maharishi Ayur-Veda Association of America 2.9 Maharishi Ayur-Veda Health Professionals Training Program Level One, Module 1 PREVENTION AND TREATMENT MODALITIES OF MAHARISHI AYUR-VEDA 1. Consciousness/ 6.Vedic exercise / Stress-reduction: Yoga asanas Transcendental MeditationTM 7. Behavioral regimens, technique and daily and seasonal advanced techniques routines to normalize biological rhythms 2. Diet and nutrition 8. Environmental Health, 3. Herbal preparations near environment (Sthapatya Veda) 4. Physiological purification procedures 9. Environmental Health, (Panchakarma) distant environment (Jyotish) 5.Vedic Vibration and Vedic Sound therapy 10. Collective health measures Copyright 2014, Maharishi Ayur-Veda Association of America 2.10 MAHARISHI AYURVEDA: RECOMMENDED READING Ayurvedic Healing: Contemporary Maharishi Ayurveda Medicine and Science, by Hari Sharma, MD and Christopher Clark, MD Total Heart Health: How to Prevent and Reverse Heart Disease with the Maharishi Vedic Approach to Health, by Robert Schneider, MD, FACC and Jeremy Fields, PhD Transcendence: Healing and Transformation through Transcendental Meditation, by Norman Rosenthal, MD Heaven’s Banquet: Vegetarian Cooking for Lifelong Health the Ayurveda Way, by Miriam K. Hospodar All of the above titles are available at Amazon.com and BarnesandNoble.com . Ayurvedic Medicine Bibliography Selected References General principles: 1. Bodeker G. Evaluating Ayurveda. Journal of Alternative and Complementary Medicine 2001;7(5): 389-392. 2. Chopra A, Doiphode V. Ayurvedic medicine: core concept, therapeutic principles, and current relevance. Medical Clinics of North America 2002; 86(1):75-89. 3. Mishra LC (ed.): Scientific Basis for Ayurvedic Therapies. CRC Press (USA); 2003. 635 pgs. 4. Sharma HM, Clark C, Micozzi M: Ayurvedic Healing: Contemporary Maharishi Ayurveda Medicine and Science. Singing Dragon Press, 2012. 320 pgs. 5. Thatt UM, Dahanukar SA. Ayur-Veda in contemporary scientific thought: Trends in pharmacology. Science 1986;7:247–251. 6. Williamson, EM (ed.): Major Herbs of Ayurveda. Churchill Livingstone, 2002. 361 pgs. 7. Nader T, Rothenberg S, Averbach R, Charles B, Fields JZ, Schneider RH. Improvements in chronic diseases with a comprehensive natural medicine approach: A review and case series. Behavioral Med 2000;26:34–46. 8. Rothenberg S, Belok S, Fields JZ. The Maharishi Vedic Medicine Chronic Disorders Program: Introduction and Case Histories. Alternative and Complementary Therapies 2003;9(4):183-190. 9. Prasher B, et al. Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. Journal of Translational Medicine 2008;6:48. 10. Patwardhan B, et al. Classification of Human Population Based on HLA Gene Polymorphism and the Concept of Prakriti in Ayurveda. The Journal of Alternative and Complementary Medicine. April 2005, 11(2): 349-353. 11. Hankey A. A test of the systems analysis underlying the scientific theory of Ayurveda's Tridosha. J Altern Complement Med. 2005 Jun;11(3):385-90. 12. Patwardhan B, Bodeker G. Ayurvedic Genomics: Establishing a Genetic Basis for Mind–Body Typologies. The Journal of Alternative and Complementary Medicine. June 2008, 14(5): 571-576. 13. Ghodke Y, Joshi K, Patwardhan B. Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability. Evid Based Complement Alternat Med. 2009 Dec 16. 14. Deocaris CC, Widodo N, Wadhwa R, Kaul SC. Merger of Ayurveda and tissue culture-based functional genomics: inspirations from systems biology.J Transl Med. 2008 Mar 18;6:14. 15. Tripathi PK, Patwardhan K, Singh G. The basic cardiovascular responses to postural changes, exercise, and cold pressor test: do they vary in accordance with the dual constitutional types of Ayurveda? Evid Based Complement Alternat Med. 2011;2011. pii: 251850. Epub 2010 Aug 30. 16. Hankey A. Ayurvedic Physiology and Etiology: The Doshas and Their Functioning in Terms of Contemporary Biology and Physical Chemistry. Journal Of Alternative And Complementary Medicine 2001;7(5):567–574. 17. Kurup RK, Kurup PA. Hypothalamic digoxin, hemispheric chemical dominance, and the tridosha theory. Int J Neurosci 2003;3(5):657-81. 1 18. Patwardhan B, Warude D, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: a comparative overview. Evidence-Based Complementary and Alternative Medicine 2005,2 (4):465-473. 19. Patwardhan B. The quest for evidence based Ayurveda: Lessons Learned. Current Science 2012, 102(25), 106-1417. 20. Das S. Susruta, the pioneer urologist of antiquity. J Urol 2001;165(5):1405–8. 21. Kansupada KB, Sassani JW. Sushruta: the father of Indian surgery and ophthalmology. Doc Ophthalmol 1997;93(1–2):159–67. 22. Patwardhan K. The history of the discovery of blood circulation: unrecognized contributions of Ayurveda masters. Adv Physiol Educ 2012;36(2):77–82. 23. Shirodkar JA, Sayyad MG, Nanal VM, Yajnik C. Anguli Parimana in Ayurveda and its association with adiposity and diabetes. J Ayurveda Integr Med 2014;5(3):177–84. 24. Raha S. Foundational principles of classical Ayurveda research. J Ayurveda Integr Med 2013;4(4):198–205. 25. Raha S. A critique of statistical hypothesis testing in clinical research. J Ayurveda Integr Med. 2011;2(3):105-14. 26. Narahari SR, Aggithaya MG, Suraj KR. A protocol for systematic reviews of Ayurveda treatments. Int J Ayurveda Res 2010;1(4):254–67. 27. Patwardhan B, Joglekar V, Pathak N, Vaidya A. Vaidya-scientists: catalysing Ayurveda renaissance. Curr Sci 2011;100(4):476–83. 28. Anantha ND. Approaches to pre-formulation R & D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes. J Ayurveda Integr Med 2013;4(1):4–8. 29. Singh RH. Perspectives in innovation in the AYUSH sector. J Ayurveda Integr Med 2011;2(2): 52–4. 30. Patwardhan B. AyuGenomics – integration for customized medicine. Indian J Nat Prod 2003;19:16–23. 31. Sumantran VN, Tillu G. Cancer, inflammation, and insights from Ayurveda. Evid Based Complement Altern Med 2012;2012:306346. 32. Chopra A, Saluja M, Tillu G. Diet, Ayurveda and interface with biomedicine. J Ayurveda Integr Med 2010;1(4):243–4. 33. Chopra A. Ayurvedic medicine and arthritis. Rheum Dis Clin North Am 2000;26(1):133– 44. 34. Patwardhan B, Vaidya ADB. Natural products drug discovery: accelerating the clinical candidate development using reverse pharmacology approaches. Indian J Exp Biol 2010;48(3):220–7. 35. Patwardhan B. Ayurveda: the “Designer” medicine: a review of ethnopharmacology and bioprospecting research. Indian Drugs 2000;37(5):213–27. 2 36. Patwardhan B, Vaidya ADB, Chorghade M, Joshi SP. Reverse pharmacology and systems approaches for drug discovery and development. Current Bioactive Compounds 2008;4(4):201–212. 37. Patwardhan B. The new pharmacognosy. Comb Chem Highthroughput Screen 2014;17(2):97. 38. Vaidya ADB. Reverse pharmacological correlates of Ayurvedic drug actions. Indian J Pharmacol 2006;38(5):311–5. 39. Patwardhan B, Mashelkar R. Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward? Drug Discov Today 2009;14(15- 16):804–11. 40. Dwivedi V, Anandan EM, Mony RS, Muraleedharan TS, Valiathan MS, Mutsuddi M, et al. In vivo effects of traditional Ayurvedic formulations in Drosophila melanogaster model relate with therapeutic applications. PLoS One 2012;7(5):e37113. 41. Chopra A, Saluja M, Tillu G. Ayurveda-modern medicine interface: a critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis. J Ayurveda Integr Med 2010;1(3):190–8. 42. Sumantran VN, Tillu G. Insights on personalized medicine from Ayurveda. J Altern Complement Med. 2013;19(4):370-5. Three-dosha theory and constitutional typology 1. Govindaraj P, Nizamuddin S, et al. Genome-wide analysis correlates Ayurveda Prakriti. Nature Scientific Reports 5, Article number: 15786 (2015); doi:10.1038/srep15786. 2. Prasher B, et al. Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. Journal of Translational Medicine 2008;6:48. 3. Patwardhan B, et al. Ayurvedic Genomics: Establishing a Genetic Basis for Mind–Body Typologies. The Journal of Alternative and Complementary Medicine. June 2008, 14(5): 571-576. 4. Rotti