In Sistemas Genómicos (ASCIRES Group) we are committed to improve our patients and their families’ life quality. Therefore, we design high quality tools for diagnosis, combining the most advanced technology with the latest scientific research. In this way, we present SG BabyTest, the most complete range of Non-Invasive Prenatal Test, developed by experts in reproductive health and genetics with over 20 years of experience in invasive prenatal diagnosis. SG BabyTest Plus: Analyses chromosomes of fetal DNA including sexual ones. SG BabyTest Advanced: NON-INVASIVE PRENATAL TEST (NIPT) Apart from chromosomes of fetal DNA, SG BABYTEST Plus / Advanced it includes the analysis of microdeletions. Sistemas Genómicos, belonging to ASCIRES Biomedical Group, is pioneering in Europe in the application of Next The most complete Generation Sequencing (NGS) in genetic diagnosis. Our Parque Tecnológico de Valencia. expertise in investigation and development of genetic Ronda G. Marconi, 6 46980 Paterna (Valencia). answer about your diagnosis services is based on our huge experience in the T (+34) 961 366 150 study of genome and human genetics. [email protected] baby's health. www.sistemasgenomicos.com What is SG SG BabyTest Plus / Advanced? How does SG BabyTest work? SG BabyTest, from one simple mother blood extraction, allows to stablish with high reliability During pregnancy, small fragments of fetal DNA circulate alongside other fragments of the risk of chromosomal abnormalities that can affect you baby’s health. It is the most maternal DNA in the mother's blood. From a maternal blood sample, we extract the DNA and complete Non-Invasive Prenatal Test as it analyses all the chromosomes: we examine it with the latest next-generation sequencing. The result is deeply examined by our • Trisomy 21 associated with Down syndrome. experts that analyses the results to determine the risk of chromosomal abnormalities. • Trisomy 18 associated with Edwards syndrome. • Trisomy 13 associated with Patau syndrome. From week 9 of pregnancy • Trisomías 16 y 22, asociadas a aborto espontáneo. • Trisomies for chromosomes 16 and 22, most often associated with spontaneous What do SG BabyTest results mean? abortion, as well as other less common types of aneuploidy such as those of chromosomes 9 and 15. Low risk High risk • Sex chromosome aneuploidies: Turner syndrome (presence of a single X sex Very low probability of fetal High probability of fetal chromosomal chromosomal aneuploidy in any of the aneuploidy in the indicated chromosome), Klinefelter syndrome (XXY), triple X syndrome and polysomy X. analysed chromosomes. chromosome. SG Baby Test Advanced, the amplified version of SG BabyTest Plus identifies* partial In this case, Sistemas Genómicos offers free invasive procedure (QF-PCR, FISH or aneuploidies (CNVs) related to 10 known microdeletion syndromes. Array) to check the results. • Angelman Syndrome. • Jacbosen Syndrome. • Prader-Willi Syndrome. • Langer-Giedion Syndrome. • 1p36 deletion. • DiGeorge II Syndrome. • Cri-du-cha Syndrome. • Phelan-McDermind Syndrome. • Wolf-Hirschhorn. • 16p11.2-p12.2 deletion. Why SG SG BabyTest? It also allows to distinguish your baby’s gender When is SG BabyTest particularly recommended ? Precision Security Experience • Advanced maternal age It detects the presence Without any risk for the The test is carried out by of chromosomal mother or the baby experts with more than • History of pregnancies with chromosomal aneuploidy. aneuploidies with as only one sample 20 years of scientific high reliability. of maternal blood and investigation • Foetuses with certain ultrasound abnormalities. is needed. experience. • High or intermediate risk established by the biochemical screening. BabyTest is a Non-Invasive Prenatal Test that does not imply any risk for the baby SG BabyTest can be used for all pregnant women who want to rule out chromosomal aneuploi- Only one sample of maternal blood is needed dies, regardless of their genetic condition or family history. Complete SG BabyTest analyses all the chromosomes and the Advanced version also includes 10 It reports CNVs related to 10 known syndromes microdeletions. * Some of these syndromes may be due to other alterations (i.e. mutations) that would not be detected by this test. .