DED UN 18 O 98 F http://www.nesacs.org N Y O T R E I T H C E N O A E S S S L T A E A C R C I N S M S E E H C C TI N December 2013 Vol. XCII, No. 4 O CA N • AMERI Monthly Meeting Summer Scholar Report A Medicinal Chemistry Symposium at Asymmetric Mannich Reactions via Pseudoephenamine Genzyme/Sanofi in Waltham Glycinamide Enolization. By Claire S. Harmange, Ian B. Seiple, Robin J. Sussman, Andrew G. Myers Photos and Reports NAS Biographical from NERM Memoirs By Morton Z. Hoffman By Michael Filosa Report from New Haven: Meeting of the Board of Directors of NERACS Morton Z. Hoffman, NESACS Representative to the NERACS Board [[email protected]] The Board of Directors of the North- east Region of the ACS, Inc. (NER- ACS) met on Saturday, October 26, 2013, in the Omni New Haven Hotel on the occasion of the Northeast Regional Meeting (NERM 2013). The NERACS Board consists of its Chair (Julianne Smist, Springfield College), Vice Chair (Richard Cobb, Eastman Kodak, retired), Secretary (Christopher Masi, Westfield State University), Treasurer (Wayne Jones, SUNY Bing- hamton), and representatives from the Doris Lewis (Suffolk University), flanked by Sharon Palmer (Amherst Regional High following local sections: Binghamton, Marinda Wu (ACS President) at left and Julie School), flanked by Marinda Wu (ACS Presi- Central Massachusetts, Central New Smist (NERACS Chair), receiving the 2013 E. dent) at left and Julie Smist (NERACS Chair), Ann Nalley Northeast Region Award for Volun- receiving the 2013 Division of Chemical Educa- York, Connecticut Valley, Cornell, teer Service to the ACS. tion Northeast Region Award for Excellence in Corning, Eastern New York, Green High School Teaching. Mountain, Maine, Mid-Hudson, New the present time, any income above (Photos by M. Z. Hoffman) Haven, Northeastern, Northern New expenditure for a NERM is shared in a financial balance sheet for the meeting York, Penn-York, Rhode Island, 40/60 ratio between NERACS and the should be in positive territory. Rochester, Western Connecticut, West- hosting local section. NERM 2015 will be held at Ithaca ern New York. Cobb expressed concern about the College, June 10-13, with Akiko Fill- In addition to executive officers paucity of nominations for the region continued on page 12 Smist, Cobb, and Masi, the following awards that are presented at NERM; in local section representatives were pres- fact, some awards cannot be given ent at the meeting: Willem Leenstra because the number of nominations (Green Mountai n), Mark Zell (Rhode does not reach the stipulated minimum. Island), Akiko Fillinger (Cornell), He asked the representatives of the Richard Hartmann (Rochester), local sections to urge their officers and Mitchell Bruce (Maine), Kenneth members to be active in the nomina- White and Jefferson Chin (New tion process. Inasmuch as there will be Haven), Morton Hoffman (Northeast- no NERM in 2014, there is now ample ern). Also in attendance were Thomas time for nominations to be generated Gilbert (ACS District I Director) and for the 2015 cycle of the following Michelle Stevenson (ACS staff liaison Northeast Region awards: Achieve- to NERM). ments in the Chemical Sciences, The Board elected Richard Cobb Excellence in High School Teaching, and Willem Leenstra as Chair and Vice Volunteer Service to the ACS, Advanc- Chair, respectively, for two-year terms ing Diversity in the Chemical Sci- (2014-15). It voted by acclamation its ences. appreciation for the service Julianne It was reported that as of that Smist provided as Chair for six years morning, more than 850 registrations from the time of the incorporation of had been received for NERM 2013; NERACS. The terms for the current over 480 oral and poster presentations Secretary and Treasurer run through were included in the program. There 2014. were 140 undergraduate research It was announced that the assets in posters, four high school student the NERACS Treasury are close to posters, and 27 exhibitors at the meet- $50,000; when they reach that level, ing. Although the room quota had not discussions will take place concerning been met at the Omni Hotel, which the long-term use of those funds. At will result in some penalty, overall the 2 The Nucleus December 2013 The Northeastern Section of the American Chemical Society, Inc. Contents Office: Anna Singer, 12 Corcoran Road, Burlington, MA 01803 (Voice or FAX) 781-272-1966. e-mail: secretary(at)nesacs.org Report from New Haven: NERACS _________________________2 NESACS Homepage: Meeting of the Board of Directors http://www.NESACS.org Officers 2013 Chair NESACS SE-MA Area Event_______________________________4 Liming Shao By Morton Z. Hoffman 158South Great Road Lincoln, MA 01773 limingshao(at)comcast.net Monthly Meeting _______________________________________5 shao(at)fas.harvard.edu 781-518-0720 A Medicinal Chemistry Symposium “Innovative Treatments for Chair-Elect Unmet Medical Needs” at Genzyme/Sanofi in Waltham, MA Catherine Costello Boston University School of Medicine 670 Albany Street, room 511 Report from New Haven: NERM ___________________________6 Boston, MA 02118-2646 by Morton Z. Hoffman cecmsms(at)bu.edu Immediate Past Chair Ruth Tanner NAS Biographical Memoirs 7 Olney Hall 415B _______________________________ Lowell, MA 01854 By Michael P. Filosa University of Mass Lowell Ruth_Tanner(at)uml.edu 978-934-3662 Summer Scholar Report _________________________________8 Secretary: Asymmetric Mannich Reactions via Pseudoephenamine Glycinamide Enolization Michael Singer Sigma-Aldrich By Claire S. Harmange, Ian B. Seiple, Robin J. Sussman, Andrew G. Myers 3 Strathmore Rd, Natick, MA 01360 774-290-1391, michael.singer(at)sial.com Photos from NERM 10 Treasurer: ____________________________________ James Piper 19 Mill Rd, Harvard, MA 01451 978-456-3155, piper28(at)attglobal.net Cover: Pictured at the first SE-MA NESACS area event held at UMass - Dart- Auditor: mouth on October 3, 2013 from L-R are Morton Hoffman, Robert Lichter, Jack Anthony Rosner Driscoll, Madeleine Jacobs, Ruth Tanner and Liming Shao. (Photo courtesy of Archivist Tim Frigo M. Z. Hoffman) Trustees: Peter C. Meltzer, Esther A. H. Hopkins, Editorial Deadlines: Michael E. Strem February 2014 Issue: December 15, 2013 Directors-at-Large March 2014 Issue: January 15, 2014 David Harris, Stephen Lantos, James Phillips, Ralph Scannell, Mary Burgess, John Burke Councilors Alternate Councilors Term Ends 12/31/2013 Alfred Viola Mark Froimowitz Michael Singer Sophia R. Su Robert Lichter Kenneth C. Mattes Mary Shultz Tim Frigo Leland L. Johnson, Jr. Mukund Chorghade Term Ends 12/31/2014 Katherine Lee C. Jaworek-Lopes The Nucleus is published monthly, except June and August, by the Northeastern Section of the American Michael P. Filosa Lawrence Scott Chemical Society, Inc. Forms close for advertising on the 1st of the month of the preceding issue. Text Doris Lewis Andrew Scholte must be received by the editor six weeks before the date of issue. Morton Z. Hoffman Raj Rajur Editor: Michael P. Filosa, Ph.D., 18 Tamarack Road, Medfield, MA 02052 Email: Patrick Gordon John Podobinski Mary Burgess Stuart Levy filosam(at)verizon.net; Tel: 508-843-9070 Term Ends 12/31/2015 Associate Editors: Myron S. Simon, 60 Seminary Ave. apt 272, Auburndale, MA 02466, Catherine E. Costello Marietta Schwartz Mindy Levine, 516-697-9688, mindy.levine(at)gmail.com Ruth Tanner JerryJasinski Board of Publications: Mary Mahaney (Chair), Vivian K. Walworth, James Phillips Dorothy J. Phillips Stephen Lantos Michaeline Chen Norton P. Peet Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Tel: 978-456-8622 Jackie O’Neil Wilton Virgo Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, All Chairs of standing Email: Manager-vincegale(at)mboservices.net; Tel: 781-837-0424 Committees, the editor Contributing Editors: Morton Hoffman, Feature Editor; Dennis Sardella, Book Reviews of THE NUCLEUS, and Calendar Coordinator: Michael P. Filosa, email: Michael.filosa(at)verizon.net the Trustees of Section Photographers: Morton Hoffman and James Phillips Funds are members of the Board of Directors. Any Proofreaders: Donald O. Rickter, Vivian K. Walworth, Mindy Levine Coun cilor of the American Chemical Soci- Webmaster: Roy Hagen ety residing within the section area is an ex Copyright 2013, Northeastern Section of the American Chemical Society, Inc. officio member of the Board of Directors. The Nucleus December 2013 3 “Everything You Always Wanted to NESACS Know about ACS, But Were Afraid to 2013 NESACS Golf Sponsors Ask” at the first Southeastern Massa- chusetts (SE-MA) area event organized LSNE Lyophilization Services of NE SE-MA Area by the Subsection Task Force (STF). Strem Chemical Among those attending were former Litman Gerson Event and current NESACS members from Sage Chemical industry and academia, nonmember Davos at UMass Dartmouth – chemists and teachers from the area, Prime Organics October 3, 2013 representatives from the Rhode Island Brian O-Reilly, LLP, Patent Litigation Local Section, and guests. The meet- By Morton Z. Hoffman ing also attracted a significant number Johnson Matthey of UMD faculty and students. IRIX Pharmaceuticals Cambridge Major O’Conner Carnathan and Mack, LLC Edelstein and Co. Chengda - Social Hour Sponsor engage members in areas that are remote from our Boston/Cambridge and environs core in which almost all Emmanuel Ojadi with MadeleineJacobs the Section’s activities take place, specifically, SE-MA (Barnstable, Bris- MadeleineJacobs meets with UMD Students Approximately 80 people came to the tol, Dukes, Nantucket, and Plymouth University of Massachusetts Dart- The purpose of the meeting was to Counties) and New Hampshire (NH). mouth (UMD) on Thursday, October 3, begin the process of exploring the fea- At the present time, STF has the fol- to hear Madeleine Jacobs, ACS Execu- sibility of establishing subsections lowing membership: Morton Hoffman tive Director and CEO, speak on within NESACS to help connect and (Boston University), Ruth Tanner (University of Massachusetts Lowell), Robert Lichter (Merrimack Consult- ants), Jack Driscoll and Jennifer Maclachlan (PID Analyzers), Robert Howard (Weeset Advisors), Jerry Jasinski (Keene State College) and Gary Weisman (University of New Hampshire).