ENVIRONMENTAL TOXICOLOGIC PATHOLOGY AND ONE HEALTH Poster Setup and Presentation Times Poster Setup Young Investigator Judging Times Sunday, June 23 ..................................................... 8:00 AM–4:00 PM Monday, June 24. .............................................10:20 AM–10:50 AM Your poster must be set up by 4:00 PM on Sunday, June 23. ..............................................................................and 2:45 PM–3:15 PM Poster Presentation Times Tuesday, June 25. ................................................ 9:35 AM–10:05 AM (Please plan to attend your posters during the following times). Poster Teardown Sunday, June 23 (Welcome Reception) ..........6:00 PM–6:30 PM Wednesday, June 26 ...............................................1:00 PM-2:00 PM Monday, June 24 ..............................................10:20 AM–10:50 AM Posters not removed by 2:00 pm, Wednesday, June 26, will be ..............................................................................and 2:45 PM–3:15 PM taken to the Registration Desk for pickup. Tuesday, June 25 ................................................. 9:35 AM–10:05 AM Wednesday, June 26 .......................................... 9:45 AM–10:15 AM 115 214 215 314 316 416 P054 P053 P052 P057 P056 P055 P049 P050 P051 P058 P059 P060 P048 P047 P046 113 212 213 312 313 412 P063 P062 P061 P043 P044 P045 P064 P065 P066 Ball P042 P041 P040 P069 P068 P067 P037 P038 P039 P070 P071 P072 P036 P035 P034 P075 P074 P073 109 208 209r 308 309 408 P031 P032 P033 P076 P077 P078 Exhibitoroom B Area P030 P029 P028 P081 P080 P079 P025 P026 P027 107(See page206 22 of the207 Final Program306 for Exhibitor307 406 Map) P082 P083 P084 P024 P023 P022 P087 P086 P085 P019 P020 P021 P088 P089 P090 P018 P017 P016 P093 P092 P091 P013 P014 P015 103 202 203 302 303 402 P094 P095 P096 P012 P011 P010 P099 P098 P097 P007 P008 P009 P100 P101 P102 101 200 201 300 301 400 P006 P005 P004 P105 P104 P103 P001 P002 P003 P106 P107 P108 ENTRANCE Visit www.toxpath.org/AM2019 for up-to-date information Poster Index 01 STP 38th Annual Symposium Poster Presentation Index Poster Categories Young Investigator Candidates .................................................P001–P021 New Technologies .........................................................................P053–P060 Biomarkers .......................................................................................P022–P024 Oncology/Carcinogenesis ...........................................................P061–P074 General Pathology/Toxicologic Pathology ............................P025–P052 Systemic/Organ-Specific Toxicologic Pathology .................P075–P106 P001 P009 Cytokine Signaling through Drosophila Mthl10 Ties Lifespan to Perinatal Di-(2-ethylhexyl) Phthalate Exacerbates Anaphylaxis in Environmental Stress Male Offspring Eui Jae Sung1, Yoichi Hayakawa2, Stephen Shears1 Emily Mackey1,2, Adam Moeser1 1NIEHS, Research Triangle Park, NC, USA. 2Saga University, Saga, Japan 1Michigan State University, East Lansing, MI, USA. 2North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA P002 Role of Necroptosis and Effects of Pharmacological Inhibition of P010 RIPK1 in Mycobacterium tuberculosis-Infected Mice Spontaneous Proliferative Typhlocolitis in FVB Mice Laine Feller, Elizabeth Ihms, William Bishai Lauren Peiffer, Cory Brayton, Karen Sfanos Johns Hopkins Department of Medicine, Baltimore, MD, USA Johns Hopkins University School of Medicine, Baltimore, MD, USA P003 P011 Expression of MARCKS Family Proteins Are Altered in a Naturally Bisphenol A and Its Analogues Induce Fibrosis in a 3D Human Occurring Organic Dust-Induced Asthma Model in Horses Uterine Fibroid Model Kaori Davis, Mary Sheats Jingli Liu, Linda Yu, Lysandra Castro, Yitang Yan, Darlene Dixon North Carolina State University, Raleigh, NC, USA NIEHS, Research Triangle Park, NC, USA P004 P012 HTLV-1 CTCF-Binding Site Is Dispensable for In Vitro Comparative Exposure Assessment in Pet Dogs: A Sentinel Immortalization and Persistent Infection In Vivo Species to Examine Health Outcomes? Michael Martinez1,2, Jacob Al-Saleem1,2, Amanda Panfil1,2, Wessel Dirksen1,2, Catherine Wise1,2, Stephanie Hammel3, Nicholas Herkert3, Jun Ma4,5, Alison Xiaogang Cheng3, Lee Ratner3, Patrick Green1,2,4 Motsinger-Reif6, Heather Stapleton3,7, Matthew Breen1,2,7,8,9 1The Ohio State University Center for Retrovirus Research, Columbus, OH, 1Program in Environmental and Molecular Toxicology, Department of USA. 2The Ohio State University Department of Veterinary Biosciences, Biological Sciences, North Carolina State University, Raleigh, NC, USA. Columbus, OH, USA. 3Washington University Division of Oncology, St. 2Department of Molecular Biomedical Sciences, College of Veterinary Louis, MO, USA. 4The Ohio State University Comprehensive Cancer Center, Medicine, North Carolina State University, Raleigh, NC, USA. 3Nicholas Columbus, OH, USA School of the Environment, Duke University, Durham, NC, USA. 4Department of Statistics, North Carolina State University, Raleigh, NC, P005 USA. 5Bioinformatics Research Center, North Carolina State University, Causes of Morbidity and Death in Sprague-Dawley and Raleigh, NC, USA. 6Biostatistics and Computational Biology Branch, National Wistar Rats in Two-Year Carcinogenicity Studies and Institute of Environmental Health Sciences, Durham, NC, USA. 7Duke Variations Over Time Cancer Institute, Durham, NC, USA. 8Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA. 9Center for Human Health and Nicholas Vetter1, Charissa Dean2, Keith Nelson2 the Environment, North Carolina State University, Raleigh, NC, USA 1Michigan State University, College of Veterinary Medicine, East Lansing, MI, 2 USA. Charles River Laboratories, Mattawan, MI, USA P013 P006 Aging-Like Spontaneous Epigenetic Silencing Facilitates WNT V600E Impact of Sex, Androgens, and Prostate Size on C57Bl6/J Mouse Activation, Stemness and BRAF -Induced Tumorigenesis Urinary Physiology: Gross and Histologic Assessment of a New Byunghak Kang1, Yong Tao1, Daniel Petkovich1, Yuba Bhandari1, Julie In1, 1 1 1 1 Platform for Toxicological Testing Genevieve Stein-O’Brien , Xiangqian Kong , Wenbing Xie , Nicholas Zachos , Shinji Maegawa2, Himani Vaidya3, Stephen Brown1, Ray-Whay Yen1, Xiaojian Hannah Ruetten, Kyle Wegner, Brett Mueller, Helen Zhang, Peiqing Wang, Shao4, Jai Thakor1, Zhihao Lu5, Yi Cai1, Yuezheng Zhang6, Izaskun Mallona7, Jaskiran Sandhu, Simran Sandhu, Zunyi Wang, Dale Bjorling, William Ricke, Miguel Peinado7, Cynthia Zahnow1, Nita Ahuja1, Elana Fertig1, Jean-Pierre Issa3, Paul Marker, Chad Vezina Stephen Baylin1, Hariharan Easwaran 1 University of Wisconsin-Madison, Madison, WI, USA 1The Johns Hopkins University School of Medicine, Baltimore, MD, USA. 2 P007 University of Texas, MD Anderson Cancer Center, Houston, TX, USA. 3Temple University, Philadelphia, PA, USA. 4McGill University, Montreal, Impact of Sex, Androgens, and Prostate Size on C57Bl6/J Mouse QC, Canada. 5Peking University Cancer Hospital & Institute, Beijing, China. Urinary Physiology: Functional Assessment of a New Platform 6University of Washington, Seattle, WA, USA. 7Germans Trias i Pujol Health for Toxicological Testing Science Research Institute (IGTP), Badalona, Spain Hannah Ruetten, Kyle Wegner, Helen Zhang, Peiqing Wang, Jaskiran Sandhu, Simran Sandhu, Dale Bjorling, William Ricke, Paul Marker, Chad Vezina University of Wisconsin Madison, Madison, WI, USA P008 Poster Withdrawn 02 Poster Index Download the 2019 Annual Meeting App for up-to-date information. ENVIRONMENTAL TOXICOLOGIC PATHOLOGY AND ONE HEALTH P014 P021 Peripheral Blood Cytokine Concentrations in Canine Effects of Intranasal Carnosine on Alpha-Synuclein (+) Neurons Glioma Patients in the Thy1-aSyn Mouse Model of Parkinson’s Disease Gregory Krane1,2, Kristen Messenger2, Christopher Mariani3,4 Josephine Brown, Kim Seroogy, Mary Beth Genter 1National Institute of Environmental Health Sciences: National Toxicology University of Cincinnati, Cincinnati, OH, USA Program: Cellular and Molecular Pathology Branch, Research Triangle Park, NC, USA. 2North Carolina State University: College of Veterinary P022 Medicine: Department of Molecular Biomedical Sciences, Raleigh, NC, Effect of Dilution on Hematologic Analysis of Rodent Blood USA. 3North Carolina State University: College of Veterinary Medicine: Samples on the ADVIA 2021i Hematology Analyzer Comparative Neuroimmunology and Neuro-Oncology Laboratory, Raleigh, Sukhdev Brar1, Keith Shockley2, Debra King1, Gregory Travlos1 4 NC, USA. North Carolina State University: College of Veterinary Medicine: 1Cellular and Molecular Pathology Branch, National Toxicology Program, Department of Clinical Sciences, Raleigh, NC, USA NIEHS, Research Triangle Park, NC, USA. 2Biostatistics and Computational Biology Branch, NIEHS, Research Triangle Park, NC, USA P015 A Time-Course Analysis of Blood-Tumor Barrier Pathology in P023 Brain Metastasis Analysis of Sugar Probes as Potential Biomarkers for Alix Dieterly1, Gozde Uzunalli1, Chinyere Kemet1, Aparna Soepriatna2, Craig Gastrointestinal Toxicity in Rats 2 3 Goergen , Michael Wendt Sayaka Kemmochi, Rio Saito, Yuka Masuyama, Hiromi Sugihara, Akira Inomata, 1 Department of Comparative Pathobiology, Purdue University, West Junichiro Hosokawa 2 Lafayette, IN, USA. Weldon School of Biomedical Engineering, Purdue Pharmaceutical & Healthcare Laboratories, FUJIFILM Corporation, 3 University, West Lafayette, IN, USA. College of Pharmacy, Department of Kanagawa, Japan