ASBMR 2010 Annual Meeting Metro Toronto Convention Centre, South Building Toronto, Ontario, Canada October 15-19, 2010 TABLE OF CONTENTS ASBMR Council/Staff .......................................................................................... v Program Committee ............................................................................................. v Abstract Reviewers ............................................................................................. vi ASBMR Committee Members/Representatives ........................................................... viii Award Winners ................................................................................................ xii Supporters ...................................................................................................... xiv General Information .......................................................................................... xv ASBMR Policies ................................................................................................ xv Continuing Medical Education Credit ..................................................................... xvi Meeting Resource Materials ................................................................................ xvii Travel Resources ............................................................................................. xviii ASBMR Networking Center ................................................................................. xix Information for Speaker and Poster Presenters ........................................................... xx WEDNESDAY, OCTOBER 13, 2010 ISCD: Bone Densitometry Course – Clinician Only ISCD Bone Densitometry Course Registration ........................................................ 1 ISCD Bone Densitometry Course: Clinician Course - Lectures 1-8 ................................ 1 THURSDAY, OCTOBER 14, 2010 ISCD: Bone Densitometry Course - Clinician Only ISCD Bone Densitometry Course Check-In ........................................................... 1 ISCD Bone Densitometry Course: Clinician Course - Lectures 9&10 ............................. 1 FRIDAY, OCTOBER 15, 2010 Day-at-a-Glance ............................................................................................ 2 Plenary Symposium I: Osteoimmunology - New Pathways Invading Bone ....................... 4 Meet-the-Professor Sessions ............................................................................... 4 Grant Writing Workshop: Show Me the Money! ..................................................... 5 Special Session for Health Professionals ................................................................ 6 Symposium - Bone and Kidney: A Dangerous Relationship ........................................ 6 Symposium - Tissue Crosstalk in the Developing Skeleton ......................................... 7 Symposium - Treating Osteoporosis In the 21st Century ............................................ 7 Symposium - Tumor Cell Signaling to Bone ........................................................... 8 Welcome and Announcements ........................................................................... 8 Presentation of the ASBMR William F. Neuman Award ........................................... 8 ASBMR/ECTS Clinical Debate - Too Much Suppression of Turnover Is Bad for Bone ...... 8 Meet-the-Professor Sessions ............................................................................... 9 Oral Poster Session: Osteoporosis: How Do Treatments Work? ................................... 9 Oral Poster Session: Signaling Pathways in Mouse Models ........................................ 10 Oral Poster Session: Bone Cell Biology & Physiology ............................................... 11 Oral Poster Session: Bone Gains and Losses ......................................................... 12 Posters and Exhibits Open ............................................................................... 13 New Investigator/ New Member/ First-time Attendee Reception ................................. 13 Minority Investigator Reception ........................................................................ 13 Welcome Reception and Plenary Poster Session ..................................................... 13 In Vivo Working Group .................................................................................. 36 Non-Invasive Assessment of Bone Microarchitecture and Function Working Group ......... 36 i Pediatric Bone and Mineral Working Group ......................................................... 37 Bone Turnover Marker Working Group .............................................................. 38 Working Group on Skeletal Aging ..................................................................... 38 Nutrition and Bone Health Working Group .......................................................... 39 Special Event: Speed Networking ....................................................................... 39 SATURDAY, OCTOBER 16, 2010 Day-at-a-Glance ........................................................................................... 40 ASBMR Networking Breakfast ......................................................................... 42 Posters Open ............................................................................................... 42 Plenary Symposium II -The Hip Fracture Epidemic ................................................ 42 Presentation of the ASBMR Gideon A. Rodan Excellence in Mentorship Award ............ 42 Presentation of the ASBMR Lawrence G. Raisz Award .......................................... 43 Exhibits Open ............................................................................................. 43 Coffee Break ............................................................................................... 43 Concurrent Oral Session 01: Osteoblasts and Bone Metabolism ................................. 43 Concurrent Oral Session 02: Bone and Cartilage: Cartilage Development and Endochondral Ossification .............................................................................................. 44 Concurrent Oral Session 03: Disorders of Bone and Mineral Metabolism: Metabolic Bone Disease ................................................................................................... 45 Concurrent Oral Session 04: Osteoporosis Assessment: Fracture Risk in Men ................. 46 Concurrent Oral Session 05: Osteoporosis Treatment ............................................... 47 Concurrent Oral Session 06: Paget’s Disease and Other Disorders of Bone ..................... 48 Poster Session I and Poster Tours ...................................................................... 49 Meet-the-Professor Sessions ............................................................................ 108 Clinical Roundtable/Case Conference: Clinical Utility of Genetic Testing – Application to Parathyroid Disorders ............................................................................... 109 State-of-the-Art Lecture - Genomic Profiling as a Tool for Discovery ......................... 109 Concurrent Oral Session 07: Osteocytes and Their Functions ................................... 109 Concurrent Oral Session 08: Osteoclasts: Factors Regulating Activity ......................... 110 Concurrent Oral Session 09: Calciotropic and Phosphotropic Hormones: Mineral Metabolism and the PTH Circuit .................................................................. 111 Concurrent Oral Session 10: Osteoporosis Epidemiology: Body Composition, Bone Mass and Fracture Risk .................................................................................... 112 Concurrent Oral Session 11: Bone Biomechanics and Quality: Preclinical Model Systems .......................................................................... 114 Concurrent Oral Session 12: Osteoporosis Therapy and Complications ....................... 115 Coffee Break .............................................................................................. 116 Symposium - Can We Talk? Cell Communication In the Skeleton ............................. 116 Symposium - Task Force Report on Atypical Femoral Fractures .............................. 116 ASBMR Town Hall Meeting .......................................................................... 117 Dancing with the ASBMR Stars - Social Event .................................................... 117 SUNDAY, OCTOBER 17, 2010 Day-at-a-Glance ......................................................................................... 118 Posters Open ............................................................................................. 121 Gerald D. Aurbach Memorial Lecture: PPARs: Tackling Frailty ............................... 121 Presentation of the ASBMR Fuller Albright Award .............................................. 121 Presentation of the ASBMR Frederic C. Bartter Award ......................................... 121 Exhibits Open ............................................................................................ 121 Coffee Break .............................................................................................. 121 Concurrent Oral Session 13: Osteoblasts: Wnt All Around ...................................... 121 Concurrent Oral Session 14: Osteoclasts: Molecular Pathways to Bone Resorption ......... 122 Concurrent Oral Session 15: Cancer and Bone: Myeloma and Treatments .................... 123 Concurrent Oral Session 16: Osteoporosis