Curriculum Vitae Annika Guse Dr. Annika Guse [email protected] Education & Training 2008 – 2012 Postdoctoral Fellow Stanford University, USA Biochemistry 2006 – 2007 Postdoctoral Fellow Technical University of Braunschweig, Germany Biotechnology 2002 – 2005 Ph.D. University of Vienna, Austria Molecular Biology graduated with distinction 1996 – 2001 B.Sc. / M.Sc. (Diplom) Technical University of Braunschweig, Germany Genetics, Cell Biology, Botany Research Experience 01/2013 – Emmy-Noether-Junior-Groupleader, University of Heidelberg, Centre for Organismal Studies (COS), Department of Molecular Evolution and Genomics, Germany Cellular basis of cnidarian symbiosis 09/2008 – 09/2012 Postdoctoral Fellow, Stanford University, Department of Biochemistry, USA Assembly mechanism of centromeres and kinetochores in higher eukaryotes Mentor: Prof. Dr. Aaron Straight 08/2006 – 08/2007 Postdoctoral Fellow, Technische Universität Braunschweig, Department of Biotechnolgy, Germany Functional knockdown of proteins at posttranslational levels with ER retained antibodies Mentor: Prof. Dr. Stefan Dübel 04/2002 – 06/2005 Ph.D., Research Institute of Molecular Pathology (IMP), Vienna, Austria AuroraB regulation of cytokinesis by phosphorylation of MKLP1 Supervisor: Prof. Dr. Michael Glotzer 2002 Research Assistant (2 months), John Innes Centre, Norwich, UK Molybdenum-cofactor-biosynthesis in E. coli Supervisor: Prof. Dr. Tracy Palmer 2001 Diploma Thesis, Technische Universität Braunschweig, Germany and John Innes Centre, Norwich, UK Thesis title: “The final step of molybdenum-cofactor-biosynthesis in E. coli: characterization of the MobA protein“ Supervisor Prof. Dr. Ralf-R. Mendel and Prof. Dr. Tracy Palmer 2000 Visiting student (5 months), John Innes Centre, Norwich, UK Supervisor: Prof. Dr. Tracy Palmer 1999 Visiting student (3 months), University of Cordoba, Spain Supervisor: Prof. Dr. Emilio Fernandez-Reyes 1 Curriculum Vitae Annika Guse Publications Hambleton, E.A.*, Guse, A.*, Pringle, J.R. Robust patterns of symbiosis specificity between Symbiodinium and the adults and larvae of Aiptasia (*equal contribution). Under review Miell, M.D.D, Fuller, C.J., Guse, A , Barysz, H.M, Downes, A., Owen-Hughes, T., Rappsilber, J., Straight, A.F., and Allshire, R.C. CENP-A confers a reduction in height on octameric nucleosomes. Nature Structural & Molecular Biology. 2013 May 5. doi: 10.1038/nsmb.2574. [Epub ahead of print] Guse, A., Fuller, C.J., Straight, A.F. A cell free system for functional centromere and kinetochore assembly. Nature Protocols 2012 Sep 20; 7(10), 1847–1869. Guse, A., Carroll, C.W., Moree, B., Fuller, C.J., Straight, A.F. (2011) In vitro centromere and kinetochore assembly on defined chromatin templates. Nature 2011 Aug 28;477(7364):354-8 Commentary by Pidoux, A. & Allshire R., (2011) Cell Division: Six degrees of separation. Nature 2011 Sep 15;477(7364):283-5 Highlighted by Huddleston JE., (2011) Cell Division: CENPA´s tail rules the centromere. Nature Review Molecular Cell Biology. 2011 Sep 23;12(10):626 Commentary by Bowers SR. & Mellone BG. (2011) Starting from Scratch: de novo kinetochore assembly in vertebrates. EMBO Journal 2011 Sep 6;30(19):3882-4 Strebe, N.*, Guse, A.*, Schüngel, M., Schirrmann, T., Hafner, M., Jostock, T., Hust, M., Müller, W., Dübel, S. (2009). Functional knockdown of VCAM-1 at the posttranslational level with ER retained antibodies. (*equal contribution). Journal of Immunological Methods 2009 Feb 28;341(1-2):30-40 Guse, A., Mishima, M., Glotzer, M. (2005). Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis. Current Biology 2005 Apr 26;15(8):778-86 Romano, A., Guse, A., Krascenicova, I., Schnabel, H., Schnabel, R., Glotzer, M. (2003). CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1. Journal of Cell Biology 2003 Apr 28;161(2):229-36 Guse, A., Stevenson, C.E., Kuper, J., Buchanan, G., Schwarz, G., Giordano, G., Magalon, A.,Mendel, R.R., Lawson, D.M., Palmer, T. (2003). Biochemical and structural analysis of the molybdenum cofactor biosynthesis protein MobA. Journal of Biological Chemistry 2003 Jul 11;278(28):25302-7 Awards & Fellowships 2012 Emmy-Noether-Award to establish an independent research lab in Germany (5 years); German Research Foundation (DFG) 2011 Selected to participate in the career academy Building Bridges, June 22-25 in Berlin, organized by the German Scholars Organization e.V. 2010 Funds to participate in the course Analytical & Quantitative Light Microscopy at the Marine Biological Laboratories (MBL) in Woods Hole, USA; German Research Foundation (DFG) 2010 Travel grant to participate in the European Career Fair in Boston, USA; German Federal Ministry of Education and Research 2009 Postdoctoral Fellowship (24 months); German Research Foundation (DFG) 2008 Dean´s Postdoctoral Fellowship (12 months); Stanford University, USA 2002 Selection into the Vienna Biocenter PhD Program, Research Institute of Molecular Pathology (IMP), Vienna, Austria 2000 Braunschweiger Bürgerpreis (500 €) for excellent studies and engagement at the Technische Universität Braunschweig, Germany 1999 Erasmus Scholarship for student research at the University of Cordoba, Spain, with Prof. Dr. E. Fernandez-Reyes 2 Curriculum Vitae Annika Guse Invited Talks & Presentations (*job talks) 2013 Braunschweig University of Technology, Institute of Plant Biology, Braunschweig, Germany (talk, 30 May) EMBO Conference, New Model Systems Linking Ecology and Evolution 1-4 May 2013, EMBL Heidelberg, Germany (talk) 2012 9th Okazaki Biology Conferences, Marine Biology II 14-19 October, Okazaki & Okinawa, JP (poster) *German Research Foundation, Bonn, Germany (talk for the “Emmy-Noether” Group Leader Selection, 25 April) Max F. Perutz Laboratories, Vienna, Austria (talk, 13 February) *Max Planck Institute for Developmental Biology, Tübingen, Germany (talk at the FML Group Leader Search Symposium, 9 February) 2011 American Society For Cell Biology, Annual Meeting 3-7 Dec 2011, Denver, USA (talk) University of Heidelberg, Centre for Organismal Studies (talk, 20 September) UC San Francisco, Bay Area Chromatin Club (talk, 25 August) UC Berkeley, Department of Bioengineering (talk, 13 April) 2010 American Society For Cell Biology, Annual Meeting 11-15 Dec 2010, Philadelphia, USA (poster) Stanford University, Department of Genetics (talk, 18 October) Stanford Biochemistry Retreat, Lake Tahoe, USA (talk, 6 October) 2009 American Society For Cell Biology, Annual Meeting 5-9 Dec 2011, San Diego, USA (poster) Stanford Biochemistry Retreat, Lake Tahoe, USA (poster) 2004 American Society For Cell Biology Summer Meeting: Cytokinesis, 22-25 July 2004, University of Vermont Burlington, USA (poster) 2002 American Society For Cell Biology, Annual Meeting, San Francisco, USA (poster) 2001 Molybdenum and Tungsten Enzymes Gordon Conference, Oxford, UK (poster) Extracurricular Activities 2011 Coral-Reef-Ecology Excursion, Dahab, Egypt, as guest scientist, lead by Prof. Christian Wild, University of Bremen, Germany, for 10 M.Sc. students (1 week) 2010 Analytical & Quantitative Light Microscopy course at the Marine Biological Laboratories (MBL), Woods Hole, USA (2 weeks) 10/2007 - 12/2007 Coral-reef fieldwork and PADI Divemaster training at the Red Sea Environmental Center (RSEC), Dahab, Egypt (3 months) 09/2005 - 06/2006 Coral-reef fieldwork in Mahahual, Mexico, with Global Vision International (GVI) (3 months), environmental fieldwork in La Hesperia, Ecuador, with Global Volunteer Network (1 month) and travel in Latin America (5 months) Teaching Experience 09/2011 Guest-Lecture “Mobile Microscopy for Coral-Reef Research using the CellScope” at a coral-reef-ecology excursion for 10 M. Sc. students in Dahab, Egypt, organized by Prof. Christian Wild, University of Bremen, Germany 08/2006 - 08/2007 Supervision of 2 Ph.D. students 08/2006 - 08/2007 Coordination of the International Graduate College (IGC) “Molecular Complexes with Biomedical Relevance”, Technical University of Braunschweig, Germany for 8 graduate students; responsible for coordination of a teaching program, a 1 day mini-symposium, invitation of guest speakers, social events and webpage maintenance 3 Curriculum Vitae Annika Guse 2006 Supervisor of “Biochemistry 1” (BB01), Technical University of Braunschweig. 8 M.Sc. students (2 weeks) 2006 Teaching English to the local community (6 adults) in Mahahual, Mexico (3 months) 1999 Tutor for “Genetic Methods” (G0), Technical University of Braunschweig, Germany. Assistance of supervising professor in experimental aspects of this course for 24 M. Sc. students (2 weeks) Press Coverage 2010 Laborjournal Portrait “Forschen in der Fremde - Annika Guse, Stanford, Kalifornien” 4 .