Efficient Professional Protein and Antibody Platforms SUN2 Antibody Basic information: Catalog No.: UPA63743 Source: Rabbit Size: 50ul/100ul Clonality: monoclonal Concentration: 1mg/ml Isotype: Rabbit IgG Purification: Protein A purified. Useful Information: WB:1:500-1:2000 IHC:1:50-1:200 Applications: FC:1:50-1:100 ICC/IF:1:50-1:100 Reactivity: Human, Mouse, Rat Specificity: This antibody recognizes SUN2 protein. Immunogen: Recombinant protein within human SUN2 aa 500-700. SUN2 (sad1/unc-84 protein-like 2), also known as UNC84B (unc-84 homolog B), FRIGG, KIAA0668 or RAB5IP, is a 717 amino acid single-pass membrane protein that contains one SUN domain and localizes to the membrane of both the nucleus and the endosome. Widely expressed in a variety of tis- sues, including lung, muscle and heart, SUN2 interacts with Rab 5A and may play a role in homotypic endosome fusion. The gene encoding SUN2 maps to human chromosome 22, which houses over 500 genes and is the second Description: smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additional- ly, translocations between chromosomes 9 and 22 may lead to the for- mation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Uniprot: Q9UH99(Human) Q8BJS4(Mouse) BiowMW: 80 kDa Buffer: 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. Storage: Store at 4°C short term and -20°C long term. Avoid freeze-thaw cycles. Note: For research use only, not for use in diagnostic procedure. Data: Gene Universal Technology Co. Ltd www.universalbiol.com Tel: 0550-3121009 E-mail: [email protected] Efficient Professional Protein and Antibody Platforms Western blot analysis of SUN2 on rat kidney tis- sue lysate using anti-SUN2 antibody at 1/2,000 dilution. Immunohistochemical analysis of paraf- fin-embedded rat epididymis tissue using an- ti-SUN2 antibody. Counter stained with hematox- ylin. Immunohistochemical analysis of paraf- fin-embedded human tonsil tissue using an- ti-SUN2 antibody. Counter stained with hematox- ylin. Immunohistochemical analysis of paraf- fin-embedded human colon tissue using an- ti-SUN2 antibody. Counter stained with hematox- ylin. Gene Universal Technology Co. Ltd www.universalbiol.com Tel: 0550-3121009 E-mail: [email protected] .