Dr Talal Al-Mayhani PhD MRCP Talal Al-Mayhani is a neurology training doctor at the Royal Free Hospital, London. He supports the teaching of 2nd year undergraduate students at Clare in neurobiology and human behaviour. His medical research focuses on the basic science of neural stem cells and brain cancer and, more recently, on engagement with clinical research. Outside medicine Talal has a degree in history and philosophy of science, and interest in education/health systems, political theory and cultural criticism. He serves as Trustee for AlThuraya Foundation, a UK-based charity for postgraduate scholarships. Talal has published essays and articles in a number of newspapers, and in his general and medical blog Braincerto. He enjoys drawing, learning languages, reading and collecting antiques. Dr Michelle Arora Michelle Arora is a Consultant Paediatrician at Addenbrooke’s Hospital and Clinical Lead for Student Experience at the University of Cambridge School of Clinical Medicine. She is a national expert on Assessment and Feedback in medical education, and represents the University of Cambridge on the Medical Schools Council Assessment Alliance. Her research interests include exploring feedback seeking in learners using qualitative methodology. She edits the Member of the Royal College of Paediatrics and Child Health (MRCPCH) written examinations for postgraduate paediatric trainees and has recently been appointed national RCPCH Undergraduate Assessment Adviser. DR SIMON BUCZACKI Simon Buczacki is an academic consultant colorectal surgeon and a Fellow and Director of Studies for Medicine at Clare College. He is a College Lecturer in anatomy and has provided supervisions in anatomy to the first and second year medics at Clare for almost ten years. Simon is also a Group Leader at the Cambridge Stem Cell Institute where his research group is interested in the interaction between genetic sub-clones and cancer cell identity. Clinically, he has a sub-specialty interest in neuro-endocrine tumour surgery. e: sjab2 at cam.ac.uk t: @SiBucz w: https://crukcambridgecentre.org.uk/users/sjab2camacuk Dr Jason Carroll Dr Carroll runs a breast cancer research lab at Cancer Research UK, investigating the mechanisms of cancer progression and drug resistance. He is also Founder and CSO of Azeria Therapeutics, which develops new cancer treatments. At Clare, he is the Hammond Careers Tutor, providing career advice for students, and running career-related workshops. One important aspect is work experience, which is becoming essential for students to gain the best jobs and graduate positions, but can be difficult to identify and organise. Part of his role at Clare is to establish work experience positions that are available only to our students. Links: Lab- http://www.carroll-lab.org.uk/ Azeria- https://www.azeriatherapeutics.com/ Professor Nicky Clayton Professor of Comparative Cognition, Department of Experimental Psychology and Scientist in Residence, Rambert Dance Company What is your subject and specific area of study? I study the evolution and development of intelligence in crows, apes and young children. I work mainly with members of the crow family (corvids) in a variety of species including jackdaws, rooks and jays, although I also have some studies on rats, bats, apes and young children. I am currently also working with Ballet Rambert to produce a new, Darwinian-themed ballet called The Comedy of Change. You can see a video of one of the dances, as well as an interview with me, here. e: [email protected] See also Nicola Clayton Profile: Nicky and the Jays, Morell, V, Science, 315, 1074-1075. Dr Laurence Drake Laurence Drake studied medicine at St John’s, Cambridge then Addenbrooke’s. After completing the West Suffolk GP Scheme he became a GP Principal at Greensands Medical Practice in Cambridgshire/Bedfordshire for 26 years. His clinical interests are ophthalmology, musculoskeletal medicine and teaching. He enjoys violin playing, hill walking, and vintage motoring and engineering. Dr Richard Dyball Richard Dyball studied veterinary medicine at Clare. As an undergraduate he became interested in the brain and later in animal welfare. After spells researching in Bristol, New York, the Babraham institute and King's College London, he returned to the Department of Anatomy (now PDN) at Cambridge and to Clare as Director of Studies in Medicine teaching anatomy and neurobiology and researching on how information is carried by nerves. He is now retired but still examines anatomy for the Royal College of Surgeons, and demonstrates in the dissecting room. Paul is recently retired from a Readership in Cancer Biology in the Department of Pathology. He was previously Director of Studies in Pathology and in Medical Sciences, and still lectures on cancer to medical, veterinary and natural science courses. His research has been on breast cancer, and in recent years has focused on the cancer genome, particularly trying to catalogue the large-scale rearrangements of DNA, such as chromosome translocations, that remain poorly understood in common cancers. This research continues as part of two large projects at the Addenbrookes Site to sequence genomes of breast and oesophageal cancers. PROFESSOR PAUL FLETCHER PhD FMedSci FRCPsych Paul is Bernard Wolfe Professor of Health Neuroscience, Wellcome Investigator and Honorary Consultant Psychiatrist. He is Director of Studies for the MST 1B students, providing lectures and supervisions on neuroscience, psychology and psychiatry. His research concerns learning, perception and decision-making and how these may be disrupted both under normal circumstances and under the influence of drugs or mental illness. He also has a growing interest in the interaction between mental health and video games and was part of the BAFTA-winning development team that created “Hellblade: Senua’s Sacrifice” which depicts psychotic illness in the context of a game. e: [email protected] t: @PaulPcf22 TEDx: https://www.youtube.com/watch?v=tV2RLLtOgL4 BAFTA: http://www.bafta.org/games/awards/british-game-0 Professor John Gibson John Gibson came to Cambridge as an undergraduate in 1978, graduating in NST Physiology in 1981, PhD in Physiology in 1984 and VetMB in 1987. He has been supervising medics, vets and NatScis since 1981. He currently teaches Systems Physiology at Clare. Aside from Cambridge he has worked in the University of Liverpool and St George’s Hospital Medical School, London. His research focuses on ion and water homeostasis in cells, with particular emphasis on red cells in sickle cell disease. Professor Bill Harris Director of Studies in Neuroscience, and Professor of Anatomy My work focuses on the following questions, and others: Where does the nervous system come from in the embryo? How does it grow to the right size and shape? How do stem cells turn into more committed neuronal progenitors and how do these cells know when to leave the cycle and differentiate into neural and glial progenitors? Once born, how do these precursors differentiate? How do they choose a particular cell type to become amongst a myriad of possible fates, and by what cellular mechanisms do these cells become properly polarised, branched, and integrated into the neural circuitry of the developing brain? What mechanisms allow neurons to send out long axons that forge pathways to their targets in the brain, and recognise specific cells within these targets? I teach Part 1B Neurobiology as a supervisor for NST students and am Director of Studies for Part II in Physiology Development and Neuroscience and in Psychology Neuroscience and Behaviour which has a share of Medics and Vets. e: [email protected] http://www.pdn.cam.ac.uk/staff/harris/index.shtml http://www.neuroscience.cam.ac.uk/directory/profile.php?harris Professor Philip Jones Phil Jones is Professor of Cancer Development at the MRC Cancer Unit, Senior Group Leader at the Wellcome Sanger Institute and an academic consultant Oncologist at Addenbrooke’s Hospital. Phil gives supervisions in anatomy to first year medics at Clare. In the clinic Phil treats patients with skin cancer. His research interest is in how normal cells accumulate mutations as we age and the impact of this on cancer development. This has led to the insight that Darwinian evolution operates in our tissues, offering the hope that interventions that alter evolutionary selection may cut our risk of getting cancer. https://www.sanger.ac.uk/science/groups/jones-group Dr Heike Laman Dr Laman is a Senior University Lecturer in the Division of Cellular and Molecular Pathology in the Department of Pathology. She is Director of Studies for IB Pathology students and Part II Pathology and Genetics students. She also supervises IB Cellular and Developmental Biology. She researches the biology of ubiquitin ligases using mouse models, trying to understand their impact in different tissues types and how their mis-regulation causes disease. She is also working on translating the potential of ubiquitin ligases into novel types of therapeutics to treat cancer and Parkinson's disease. Daniel Marcos Dr Daniel Marcos is a Postdoctoral Researcher in the Department of Oncology since 2015 and Clare College Research Associate since 2016. He supervises Neurobiology Natural Sciences Tripos 1B students (2nd year undergraduate). He did his undergraduate training and PhD in the Department of Biochemistry (University of Extremadura, Spain) in the field of calcium pumps and their relationship with the beta-amyloid peptide. He spent time in the Centre of Molecular Biology (Madrid; Spain), Catholic University of Leuven (Belgium) and Centre for Membrane Pumps in Cells and Disease (Aarus, Denmark) where he reached a deeper understanding of the mechanism of calcium pumps. Now Daniel is based in the Department of Oncology studying the post translational modifications of ASCL1, a transcription factor master regulator of the nervous system development with an important role in the Neuroblastoma, the most common childhood cancer. He has also developed an interest in the understanding of the molecular basis of brain disorders.