Anti-MRPS17 monoclonal antibody, clone FQS23694 (DCABH-6110) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Rabbit monoclonal to MRPS17 Antigen Description Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. Immunogen Recombinant fragment within Human MRPS17. The exact sequence is proprietary.Database link: Q9Y2R5 Isotype IgG Source/Host Rabbit Species Reactivity Human Clone FQS23694 Purity Tissue culture supernatant Conjugate Unconjugated Applications IHC-P, WB, ICC/IF, IP Positive Control HeLa, HepG2 and U937 cell lysate; Human kidney and liver tissue; HeLa cells Format Liquid Size 100 μl Buffer pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 0.05% BSA, 50% Glycerol 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Preservative 0.01% Sodium Azide Storage Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Ship Shipped at 4°C. GENE INFORMATION Gene Name MRPS17 mitochondrial ribosomal protein S17 [ Homo sapiens ] Official Symbol MRPS17 Synonyms MRPS17; mitochondrial ribosomal protein S17; 28S ribosomal protein S17, mitochondrial; 28S ribosomal protein S17; mitochondrial; HSPC011; MRP S17; RPMS17; S17mt; MRP-S17; Entrez Gene ID 51373 Protein Refseq NP_057053 UniProt ID Q9Y2R5 Chromosome Location 7p11-q11.21 Function rRNA binding; structural constituent of ribosome; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.