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Institution Legend Street City / ZIP-Code Book with online Textbook Country Book CD-ROM files/update with CD-ROM Email Date Signature Book Springer Customer Service Center GmbH, Haberstrasse 7, 69126 Heidelberg, Germany The first € price and the £ price are net prices, subject to local VAT. Prices indicated with * include VAT for books; DVD Set with DVD 7 Call: + 49 (0) 6221-345-4301 7 Fax: +49 (0)6221-345-4229 the € (D) includes 7% for Germany, the € (A) includes 10% for Austria. Prices indicated with ** include VAT for elec- 7 Email: [email protected] 7 Web: springer.com tronic products; 19% for Germany, 20% for Austria. All prices exclusive of carriage charges. Prices and other details are subject to change without notice. All errors and omissions excepted. H93635 springer.com Natural Sciences & Engineering | Biomedicine H. Heng, Wayne State University School of Medicine, Detroit, MI, USA 4D-Genomics Genome Dynamics and Constraint in Evolution Proposing that genes and genomes are discrete biological entities with genomes controlling evolu- tionary selection, this much-needed survey maps the contours of a new area of genome research that resolves troubling paradoxes and is key to our L. Annunziato, University of Naples Federico II, Italy Current Topics in Microbiology decoding efforts. (Ed) and Immunology Due March 2013 Sodium Calcium Exchange: Monograph A Growing Spectrum R. W. Compans, M. D. Cooper, F. Melchers, Series editor: M. B. Oldstone, P. K. Vogt, T. Honjo, 2013. Approx. 250 p. Hardcover of Pathophysiological Y. Y. Gleba, B. Malissen, Y. Kawaoka, K. Aktories, 7 approx. € 139,95 | £126.50 R. Rappuoli, J. E. Galan 7 approx. * € (D) 149,75 | € (A) 153,94 | sFr 186,50 Implications ISBN 978-1-4614-3919-6 Proceedings of the 6th International Volume 364 Conference on Sodium Calcium Exchange A. Rummel, T. Binz, Medizinische Hochschule Due November 2012 Hannover, Germany (Eds) Contributed volume Botulinum Neurotoxins 2013. XXV, 463 p. 133 illus., 53 in color. (Advances in Due December 2012 Experimental Medicine and Biology, Volume 961) Contributed volume Hardcover 7 approx. € 209,00 | £186.50 2013. VII, 389 p. 46 illus., 36 in color. Hardcover 7 approx. * € (D) 223,63 | € (A) 229,90 | sFr 275,50 7 € 139,95 | £126.00 ISBN 978-1-4614-4755-9 7 * € (D) 149,75 | € (A) 153,94 | sFr 186,50 ISBN 978-3-642-33569-3 A. Boullerne, University of Illinois at Chicago, IL, A. Dey, Anna University, Chennai, India (Ed) T. Jue, University of California Davis, California, US; USA; D. Osterhout, SUNY Upstate Medical University, K. Masuda, Kanazawa University, Kakuma-machi, Syracuse, NY, USA Cytochrome P450 2E1: Its Kanazawa-city, Ishikawa, Japan (Eds) Methods of Glial Cell Culture Role in Disease and Drug Application of Near Infrared Metabolism This book outlines methods for the isolation, Spectroscopy in Biomedicine purification and propagation of glial cells, such The book deals with various clinical aspects of This volume balances the need for physical sci- as oligodendrocytes, astrocytes, microglia and cytochrome P450 2E1 (CYP2E1) which is a potent ence/mathematics formalism with a demand Schwann cells. It provides clear and detailed source for oxidative stress. Oxidative stress is for biomedical perspectives. It details current protocols that are designed to be informative and critical for pathogenesis of diseases and CYP2E1 instrumentation and techniques as well as illus- easy to reproduce. is a major contributor for oxidative stress. Several trates current applications in addressing complex clinical disorders are associated with changes in biology questions. Due January 2013 regulation of CYP2E1 and the consequent abnor- Monograph malities which include alcoholic liver disease, al- Due March 2013 coholic pancreatitis, carcinogenesis, non-alcoholic 2013. 210 p. 150 illus., 60 in color. Hardcover Contributed volume fatty liver disease, non-alcoholic steatohepatitis, 7 approx. € 74,95 | £67.99 obesity, hepatitis C virus infection, reproductive 2013. XVI, 125 p. 70 illus., 22 in color. (Handbook of 7 approx. * € (D) 80,20 | € (A) 82,45 | sFr 107,50 organ toxicity, hepatocellular and cholestatic liver Modern Biophysics, Volume 4) Hardcover ISBN 978-1-4614-5923-1 cirrhosis, inhibition of bone repair, cross-tolerance 7 approx. € 154,95 | £139.50 in smokers and people treated with nicotine, 7 approx. * € (D) 165,80 | € (A) 170,44 | sFr 222,00 disorders of central nervous system, changes in ISBN 978-1-4614-6251-4 metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Due February 2013 Contributed volume 2013. X, 290 p. 35 illus., 5 in color. Hardcover 7 € 139,95 | £126.00 7 * € (D) 149,75 | € (A) 153,94 | sFr 186,50 ISBN 978-94-007-5880-3 1 Natural Sciences & Engineering | Biomedicine springer.com P. D. Katsikis, Drexel University College of Medicine, J. L. Mehta, University of Arkansas for Medical D. H. O‘Day, A. Catalano, University of Toronto at Philadelphia, PA, USA; S. P. Schoenberger, La Jolla Sciences, Little Rock, AR, USA; N. S. Dhalla, Mississauga, ON, Canada (Eds) Institute for Allergy and Immunology, CA, USA; University of Manitoba, Winnipeg, MB, Canada (Eds) B. Pulendran, Emory University, Atlanta, GA, USA Proteins of the Nucleolus (Eds) Biochemical Basis and Regulation, Translocation, & Biomedical Crossroads Between Innate and Therapeutic Implications of Functions Adaptive Immunity IV Angiogenesis This book offers insight into the nucleolus of the past, present and future, as well its regulation, Leading authorities on the biochemistry of this This volume presents reviews derived from work translocation, and biomedical function. Coverage complex physiological process explain its critical presented at the Aegean Conference: “4th Cross- includes nucleologenesis, nucleolar architecture, role in human growth and development as well roads between innate and adaptive immunity,“ and the relationship between the nucleolus and as the pathogenesis of cancer, heart disease, and which attracted scientists from all over the world cancer. other morbidities. The book fully updates the cur- to discuss their latest findings on Innate and rent literature. Adaptive immunity. Due January 2013 Due February 2013 Contributed volume Due February 2013 Contributed volume Contributed volume 2013. Approx. 455 p. 46 illus., 18 in color. Hardcover € 149,95 | £135.00 2013. Approx. 300 p. (Advances in Biochemistry in 7 2013. 300 p. (Advances in Experimental Medicine * € (D) 160,45 | € (A) 164,94 | sFr 200,00 Health and Disease, Tentative volume 6) Hardcover 7 and Biology, Volume 785) Hardcover ISBN 978-94-007-5817-9 7 approx. € 154,95 | £139.50 7 approx. € 104,95 | £93.00 7 approx. * € (D) 165,80 | € (A) 170,44 | sFr 206,50 7 approx. * € (D) 112,30 | € (A) 115,45 | sFr 137,50 ISBN 978-1-4614-5856-2 ISBN 978-1-4614-6216-3 A. Meissner, Harvard University, Cambridge, MA, USA; J. Walter, Saarland University, Saarbrücken, Germany (Eds) Epigenetic Mechanisms in Cellular Reprogramming Offering an overview of current topics and con- cepts concerning mechanisms and consequences of epigenetic reprogramming, this book addresses biomedical researchers in search of more detailed knowledge of novel mechanisms and methods of J. W. Laan, National Institute, Bilthoven, The study. M.‑O. Parat, University of Queensland School of