Anti-IPO7 Polyclonal Antibody Cat: K007740P Summary: 【Product name】: Anti-DCN antibody 【Source】: Rabbit 【Isotype】: IgG 【Species reactivity】: Human Mouse 【Swiss Prot】: O95373 【Gene ID】: 10527 【Calculated】: MW:120kDa 【Observed】: MW:130kDa 【Purification】: Affinity purification 【Tested applications】: WB IHC 【Recommended dilution】: WB 1:500-2000. IHC 1:25-100. 【WB Positive sample】: HeLa,293T 【IHC Positive sample】: Human stomach cancer 【Subcellular location】: Cytoplasm Nucleus 【Immunogen】: A synthetic peptide of human IPO7 【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information Verified picture Western blot analysis with IPO7 antibody Immunohistochemistry of paraffin-embedded diluted at 1:1000;Lane: HeLa,293T Human stomach cancer with IPO7 antibody diluted at 1:50 Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information.