JOURNAL OF VIROLOGY VOLUME 68 * APRIL 1994 * NUMBER 4 Arnold J. Levine, Editor in Chief (1994) Vincent R. Racaniello, Editor (1997) Princeton University Columbia University Princeton, N.J. Peter M. Howley, Editor (1998) New York, N.Y Harvard Medical School John M. Coffin, Editor (1996) Boston, Mass. Thomas E. Shenk, Editor (1994) Tufts University Medical School Princeton University Boston, Mass. Michael B. A. Oldstone, Editor (1994) Princeton, N.J. Scripps Clinic & Research Foundation Ronald C. Desrosiers, Editor (1998) La Jolla, Calif. Joseph Sodroski, Editor (1998) Harvard Medical School Dana-Farber Cancer Institute Boston, Mass. Carol Prives, Editor (1996) Boston, Mass. Columbia University Mary K. Estes, Editor (1998) New N.Y Inder M. Verma, Editor (1998) Baylor College of Medicine York, The Salk Institute Houston, Tex. San Diego, Calif. EDITORIAL BOARD Rafi Ahmed (1994) Harry B. Greenberg (1995) Elizabeth Moran (1996) Priscilla A. Schaffer (1996) Carl C. Baker (1994) Hidesaburo Hanafusa (1995) Bernard Moss (1995) Heinz Schaller (1995) Amiya K. Banerjee (1996) Ed Harlow (1996) Richard W. Moyer (1995) Sondra Schlesinger (1995) Kenneth L. Berns (1994) Gary S. Hayward (1996) James Mullins (1996) Robert J. Schneider (1994) Joseph B. Bolen (1994) Ari H. Helenius (1996) Brian R Murphy (1994) Manfred H. Schubert (1996) Thomas J.'Braciale (1994) Virginia S. Hinshaw (1996) Nicholas A. Muzyczka (1996) Bartholomew M. Sefton (1994) John Brady (1994) David D. Ho (1996) Gerald Myers (1995) Bert L. Semler (1995) Thomas R. Broker (1995) James M. Hogle (1994) Gary J. Nabel (1996) David A. Shafritz (1994) Michael J. Buchmeier (1995) John J. Holland (1996) Opendra Narayan (1994) Yosef Shaul (1995) Robert Callahan (1994) Kathryn V. Holmes (1994) Neal Nathanson (1996) Saul J. 'Silverstein (1994) Barrie J. Carter (1996) Nancy Hopkins (1995) Jay A. Nelson (1994) Daniel T. Simmons (1995) Mark Challberg (1995) Stephen H. Hughes (1994) Joseph R. Nevins (1994) Anna Marie Skalka (1996) Irvin S. Y. Chen (1996) Eric Hunter (1996) Dennis O'Callaghan (1995) Nahum Sonenberg (1996) Bruce W. Chesebro (1994) Tony Hunter (1995) Peter Palese (1994) Arne Stenlund' (1995) Donald M. Coen (1995) Nancy A. Jenkins (1995) Enzo Paoletti (1994) Mark F. Stinskj (1995) Gary H. Cohen (1-994) Richard A. Katz (1996) Takis S. Papas (1996) Jonathan P. Stoye (1996) Charles N. Cole (1995) Jack D. Keene (1994) Tristram G. Parslow (1996) James H. Strauss (1996) Peter L Collins (1994) Thomas J. Kelly (1994) J.' Thomas Parsons (1995) Bill Sugden (1996) Richard C. Condit (1995) Elliott Kief (1996) C. David Pauza (1996) Jesse Summers (1995) Neal G. Copeland (1995) Karla Kirkegaard (1996) David J. Pintel (1995) Ron Swanstrom (1996) Richard J. Courtney (1995) Geofy K Kitchingman (1995) Abraham Pinter (1994) Peter J. Tattersall (1995) Clyde S. Crumpacker II (1994) Daniel F. Klessig (1994) James M. Pipas (1996) John M. Taylor (1996) Bryan R, Cullen (1996) David M. Knipe (1994) Lewis I. Pizer (1996) Mary J. Tevethia (1996) Thomas Curran (1994) Hsing-Jien Kung (1996) Nancy Raab-Traub (1996) Satvir S. Tevethia (1994) Samuel Dales (1994) Ching-Juh Lai (1996) Arnold B. Rabson (1996) David A. Thorley-Lawson (1994) Daniel DiMaio (1994) Michael Lai (1994) R Frank Ramig (1994) Paula Traktman (1995) Walter Doerfler (1995) Jonathan Leis (1994) Dan S. Ray (1995) Didier Trono (1996) Elvera Ehrenfeld (1995) Jack Lenz (1996) Alan R. Rein (1996) Philip N. Tsichlis (1995) Robert N. Eisenman (1994) Norman L Letvin (1995) Carol S. Reiss (1996) Kenneth L. Tyler (1994) John Elder (1996) Maxine Linial (1994) Solon L Rhode (1995) Luis V. Villarreal (1994) Michael Emerman (1995) David M. Livingston (1994) William S. Robinson (1995) Peter K. Vogt (1996) Suzanne U. Emerson (1995) Douglas R Lowy (1995) Bernard Roizman (1994) Edward K. Wagner (1995) Lynn W. Enquist (1994) Paul J. Maddon (1996) John K. Rose (1994) Robert G. Webster (1996) Hung Fan (1994) James L Manley (1995) Craig Rosen (1996) Raymond M. Welsh (1994) Ellen Fanning (1994) Malcolm A. Martin (1995) Naomi Rosenberg (1995) Gail Wertz (1994) Bernard Fleckenstein (1996) William S. Mason (1994) Barry T. Rouse (1996) J. Lindsay Whitton (1995) Jane Flint (1996) Michael B. Mathews (1994) Roland R Rueckert (1994) Reed B. Wickner (1994) William R Folk (1994) Alan McLachlan (1996) Norman P. Salzman (1996) John W. Wills (1995) Paul D. Friesen (1994) A. Dusty Miller (1994) Charles E. Samuel (1995) Eckard Wimmer (1994) Denise A. Galloway (1995) Lois I. Miller (1994) Richard Jude Samulski (1995) Flossie Wong-Staal (1996) Don Ganem (1994) Edward S. Mocarski (1996) Peter Sarnow (1996) Moshe Yaniv (1995) Costa P. Georgopoulos (1995) Peter Model (1995) Nava Sarver (1996) Charles Hamish Young (1995) Joseph C. Glorioso (1995) John P. Moore (1996) Dorothea L Sawicki (1994) Harald zur Hausen (1995) Barbara H. Iglewski, Chairman, Publications Board Linda M. Illig, Director, Journals Judith Nedrow, Production Editor Arthur Gelmis, Assistant Production Editor The Journal of Virology, a publication of the American Society for Microbiology (ASM), 1325 Massachusetts Ave., N.W., Washington, DC 20005-4171, is devoted to the dissemination of fundamental knowledge concerning viruses of bacteria, plants, and animals. Investigators are invited to submit reports of original research in all areas of basic virology, including biochemistry, biophysics, genetics, immunology, morphology, physiology, and pathogenesis and immunity. Instructions to authors are published in the January issue each year; reprints are available from the editors and the Journals Division. The Journal is issued monthly, one volume per year. The nonmember print subscription prices are $380 (U.S.) (Canadians add 7% GST) and $454 (other countries) per year; single copies are $43 (Canadians add 7% GST). The member print subscription prices are $81 (U.S.) (Canadians add 7% GST) and $106 (other countries); single copies are $11 (Canadians add 7% GST). For prices of CD-ROM versions, contact the Subscriptions Unit, ASM. Correspondence relating to subscriptions, defective copies, missing issues, and availability of back issues should be directed to the Subscriptions Unit, ASM; correspondence relating to reprint orders should be directed to the Reprint Order Unit, ASM; and correspondence relating to disposition of submitted manuscripts, proofs, and general editorial matters should be directed to the Journals Division, American Society for Microbiology, 1325 Massachusetts Ave., N.W., Washington, DC 20005-4171. Phone: (202) 737-3600. Claims for missing issues from residents of the United States, Canada, and Mexico must be submitted within 3 months after publication of the issues; residents of all other countries must submit claims within 6 months of publication of the issues. Claims for issues missing because of failure to report an address change or for issues "missing from files" will not be allowed. Second-class postage paid at Washington, DC 20005, and at additional mailing offices. POSTMASTER: Send address changes to Journal of Virology, ASM, 1325 Massachusetts Ave., N.W., Washington, DC 20005-4171. Made in the U.S.A. Printed on acid-free paper. ISSN 0022-538X CODEN: JOVIAM Copyright © 1994, American Society for Microbiology. All Rights Reserved. The code at the top of the first page of an article in this journal indicates the copyright owner's consent that copies of the article may be made for personal use or for personal use of specific clients. This consent is given on the condition, however, that the copier pay the stated per-copy fee through the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923, for copying beyond that permitted by Sections 107 and 108 of the U.S. Copyright Law. This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works, or for resale. Author Index Aasted, Bent, 2720 Dow, Steven W., 2230 Jansen-Diirr, Pidder, 2206 Marion, Patricia L., 2091 Adelmant, Guillaume, 2097 Dubin, Gary, 2478 Javaherian, Kashi, 2624 Markham, Phillip, 2693 Akahane, Yoshihiro, 2671 Jenkins, Nancy A., 2320 Martin, Jennifer E., 2649 Albrecht, Julia, 2142 Eddleston, Michael, 2383 Jeong, Yong Seok, 2615 Martin, Malcolm A., 2503 Alexandersen, Soren, 2720 Eilers, Martin, 2206 Jiang, Min, 2065 Mason, William S., 2286 Alford, Patricia, 2693 Einfeld, David A., 2513 Johansen, Bjarne, 2398 Mayumi, Makoto, 2671 Allan, Jonathan, 2693 Eisenberg, Roselyn J., 2529 Johansen, Tere, 2398 McDougall, Ann S., 2151 Aloni, Yosef, 2741 Elkins, William R., 2649 Johnson, Marion D., III, 2331 McGregor, Martha W., 2051 Alonso-Caplen, Firelli, 2433 Engelke, Ute, 2752 Johnson, Philip R., 2649 McKnight, Kevin L., 2683 Angliker, Herbert, 2772 Ensoli, Barbara, 2677 Johnston, Robert E., 2683 Mehdi, Haider, 2415 Anlar, Fehim Yasar, 2415 Erickson, Ann L., 2756 Joswig, Silvia, 2206 Menendez-Arias, Luis, 2313 Menzo, Stefano, 2495 Bachmann, Barbara, 2765 Fauci, Anthony S., 2598 Kabat, David, 2570 Miller, Lois K., 2521 Baer, Margaret L., 2194 Fink, D. J., 2239 Kaiwar, Ravi, 2118 Mindich, Leonard, 2331 Bagnarelli, Patrizia, 2495 Folks, Thomas M., 2726 Kalyanaraman, Vaniambadi, Miyakawa, Yuzo, 2671 Balfe, Peter, 2161 Franchini, Genoveffa, 2693 2693 Mizushima, Hiroto, 2731 Bargmanti, William, 2073 Freed, Eric O., 2503 Kaplan, Michael J., 2415 Moens, Ugo, 2398 Basu, Mitali, 2478 Friedman, H. M., 2478 Katzenstein, Gil E., 2135 Monastyrskaya, Katherine, Basu, Saswata, 2478 Friedrich, Thomas D., 2355 Kaushal, S., 2468 2169 Bayer, Robert, 2415
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