OriGene Technologies, Inc. OriGene Technologies GmbH 9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-888-267-4436 Phone: +49-5221-34606-0 Fax: +1-301-340-8606 Fax: +49-5221-34606-11 [email protected] [email protected] AP12093PU-N Polyclonal Antibody to Ubiquilin-2 (UBQLN2) (C-term) - Purified Alternate names: Chap1, DSK2 homolog, HRIHFB2157, N4BP4, PLIC-2, PLIC2, Protein linking IAP with cytoskeleton 2, Ubiquitin-like product Chap1/Dsk2 Quantity: 0.4 ml Concentration: lot specific Background: Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low. Uniprot ID: Q9UHD9 NCBI: 9606 GeneID: 29978 Host / Isotype: Rabbit / Ig Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Dsk2. Applications: ELISA: 1/1,000. Western Blot: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: This antibody is specific to Ubiquilin-2 (UBQLN2/DSK2) (C-term). Species: Human. Other species not tested. Add. Information: Predicted Molecular weight: 65765 Da Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures. General Readings: 1. Walters, K.J., et al., Biochemistry 41(6):1767-1777 (2002). 2. Kleijnen, M.F., et al., Mol. Cell 6(2):409-419 (2000). 3. Ueki, N., et al., Nat. Biotechnol. 16(13):1338-1342 (1998). For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. OG/20130805 1 / 2 AP12093PU-N: Polyclonal Antibody to Ubiquilin-2 (UBQLN2) (C-term) - Purified Pictures: Western blot analysis of anti-Dsk2 Pab (C- term) (Cat. #AP12093PU-N) to detect Dsk2 in HeLa cell lysate. For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. OG/20130805 2 / 2 Powered by TCPDF (www.tcpdf.org).