Cochrane Library Cochrane Database of Systematic Reviews Minimally invasive surgical techniques versus open myomectomy for uterine fibroids (Review) Bhave Chittawar P, Franik S, Pouwer AW, Farquhar C Bhave Chittawar P, Franik S, Pouwer AW, Farquhar C. Minimally invasive surgical techniques versus open myomectomy for uterine fibroids. Cochrane Database of Systematic Reviews 2014, Issue 10. Art. No.: CD004638. DOI: 10.1002/14651858.CD004638.pub3. www.cochranelibrary.com Minimally invasive surgical techniques versus open myomectomy for uterine fibroids (Review) Copyright © 2014 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd. Cochrane Trusted evidence. Informed decisions. Library Better health. Cochrane Database of Systematic Reviews T A B L E O F C O N T E N T S HEADER......................................................................................................................................................................................................... 1 ABSTRACT..................................................................................................................................................................................................... 1 PLAIN LANGUAGE SUMMARY....................................................................................................................................................................... 2 SUMMARY OF FINDINGS.............................................................................................................................................................................. 3 BACKGROUND.............................................................................................................................................................................................. 5 OBJECTIVES.................................................................................................................................................................................................. 6 METHODS..................................................................................................................................................................................................... 6 RESULTS........................................................................................................................................................................................................ 9 Figure 1.................................................................................................................................................................................................. 10 Figure 2.................................................................................................................................................................................................. 12 Figure 3.................................................................................................................................................................................................. 13 Figure 4.................................................................................................................................................................................................. 14 Figure 5.................................................................................................................................................................................................. 14 Figure 6.................................................................................................................................................................................................. 15 Figure 7.................................................................................................................................................................................................. 16 DISCUSSION.................................................................................................................................................................................................. 17 AUTHORS' CONCLUSIONS........................................................................................................................................................................... 19 ACKNOWLEDGEMENTS................................................................................................................................................................................ 19 REFERENCES................................................................................................................................................................................................ 20 CHARACTERISTICS OF STUDIES.................................................................................................................................................................. 22 DATA AND ANALYSES.................................................................................................................................................................................... 38 Analysis 1.1. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 1 Postoperative pain 40 at 6 hours............................................................................................................................................................................................... Analysis 1.2. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 2 Postoperative pain 40 at 24 hours............................................................................................................................................................................................. Analysis 1.3. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 3 Postoperative pain 41 at 48 hours............................................................................................................................................................................................. Analysis 1.4. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 4 Perioperative in- 41 hospital adverse events; unscheduled return to theatre................................................................................................................... Analysis 1.5. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 5 Perioperative in- 42 hospital adverse events; laparoconversion......................................................................................................................................... Analysis 1.6. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 6 Perioperative in- 43 hospital adverse events; injury to pelvic organs................................................................................................................................ Analysis 1.7. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 7 In-hospital adverse 43 events; postoperative fever.................................................................................................................................................................. Analysis 1.8. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 8 Haemoglobin drop 44 (g/dL)...................................................................................................................................................................................................... Analysis 1.9. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 9 Length of hospital 44 stay (hours)............................................................................................................................................................................................ Analysis 1.10. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 10 Operating time 44 (minutes)................................................................................................................................................................................................ Analysis 1.11. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 11 Improvement in 45 menstrual symptoms such as heaviness of periods, or pressure symptoms.................................................................................... Analysis 1.12. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 12 Recurrence of 45 fibroids................................................................................................................................................................................................... Analysis 1.13. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 13 Repeat 46 myomectomy......................................................................................................................................................................................... Analysis 1.14. Comparison 1 Laparoscopic myomectomy versus open myomectomy (all types), Outcome 14 Hysterectomy at 46 a later time............................................................................................................................................................................................ APPENDICES................................................................................................................................................................................................. 47 HISTORY.......................................................................................................................................................................................................