USOO966236OB2 (12) United States Patent (10) Patent No.: US 9,662,360 B2 Squires (45) Date of Patent: May 30, 2017 (54) TREATMENT OF HERPES, PSEUDOMONAS, (56) References Cited STAPH, AND HEPATITIS U.S. PATENT DOCUMENTS (71) Applicant: Meryl J. Squires, Barrington, IL (US) 4,200,655 A 4, 1980 Farah et al. (72) Inventor: Meryl J. Squires, Barrington, IL (US) 23.63 A ck 3. My . A61K 8,37 (73) Assignee: Meritus Corporation (DM) 5,167,952 A 12/1992 McHugh 424f735 5,221,533 A 6/1993 Perlman (*) Notice: Subject to any disclaimer, the term of this 5,387,611 A 2f1995 Rubinstein patent is extended or adjusted under 35 E. f 2.88. S. Jr. U.S.C. 154(b) by 0 days. 6.350.784 B 2.2002 Squires 6,355,684 B1* 3/2002 Squires .................. A61K9/145 (21) Appl. No.: 14/961,035 514,642 7,071,233 B2 7/2006 Squires (22) Filed: Dec. 7, 2015 2003/O113357 A1* 6, 2003 Bell ....................... A61K 8.345 424/401 (65) Prior Publication Data * cited by examiner US 2016/O151436A1 Jun. 2, 2016 Primary Examiner — Rei-Tsang Shiao Related U.S. Application Data (74) Attorney, Agent, or Firm — Tolpin & Partners, PC; (63) Continuation-in-part of application No. 14/848,525, Thomas W. Tolpin filed on Sep. 9, 2015, now abandoned, which is a continuation-in-part of application No. 12/248,402, (57) ABSTRACT filed on Oct. 9, 2008, now abandoned. An improved method (process) is provided to treat herpes, pseudomonas, staphylococcus (staph), and hepatitis and (51) Int. Cl. help treat or alleviate cold Sores, rashes, skin conditions, or A63/335 (2006.01) Symptoms resulting from herpes, pseudomonas, Staph, and A6 IK 36/28 (2006.01) hepatitis. The method uses a special medicinal composition A6 IK 3/4 (2006.01) which can be self-administered and maintained for a pre A6 IK 3/466 (2006.01) scribed time. The attractive medicinal composition can A6 IK3I/045 (2006.01) comprise a quaternary ammonium salt Surfactant, a skin A6 IK 9/00 (2006.01) protectant and an alcohol. The quaternary ammonium salt A6 IK 47/10 (2017.01) Surfactant can comprise benzalkonium halide, preferably A6 IK 47/6 (2006.01) benzalkonium chloride. The skin protectant can comprise A6 IK 47/8 (2017.01) Allantoin. The alcohol can serve as a pain reliever and can (52) U.S. Cl. comprise benzyl alcohol. The medicinal composition can CPC ............ A61K 36/28 (2013.01); A61K 9/0014 also include other compounds, additives, herbal extracts (2013.01); A61 K3I/045 (2013.01); A61 K and/or carriers. Desirably, the medicinal composition is 3 1/14 (2013.01); A61K 31/4166 (2013.01); maintained on the infected regions until external symptoms A61K 47/10 (2013.01); A61K 47/16 (2013.01); and physical manifestations of the symptoms resulting from A61K 47/186 (2013.01) herpes, pseudomonas, hepatitis, or Staph Substantially dis (58) Field of Classification Search appear from the infected regions. USPC .......................................................... 514/642 See application file for complete search history. 13 Claims, No Drawings US 9,662,360 B2 1. 2 TREATMENT OF HERPES, PSEUDOMONAS, people with a Suppressed immune system, Such as people STAPH, AND HEPATITIS with cancer, AIDS or an organ transplant. These people are at higher risk of more severe infection. CROSS REFERENCES TO RELATED If the Sore appears on the Soft tissues inside the mouth, it APPLICATION may be a canker sore. Cold sores or fever blisters and are quite different from canker Sores, a condition people some This application is a continuation-in-part of U.S. patent times associate them with. Cold sores are caused by the application Ser. No. 14/848,525 filed on Sep. 9, 2015, which herpes simplex virus and they're contagious. Canker Sores, is a continuation-in-part of U.S. patent application Ser. No. which arent contagious, are ulcers that occur in the soft 12/248,402 filed on Oct. 9, 2008 10 tissues inside your mouth, places where cold Sores don't occur. Cold Sores are common occurrences although cold BACKGROUND OF THE INVENTION Sores may not be completely curable or prevented, medicinal treatments can help reduce their frequency and limit the The present invention relates to medicinal treatment, and duration of their occurrence. more particularly, to medicinal treatments and preventions 15 to treat herpes, pseudomonas, staphylococcus (staph), and Complete healing of cold sores or fever blisters can take hepatitis and help treat or alleviate cold Sores, rashes, skin 7 to 10 days or more. For some people, however, cold sores conditions, or symptoms resulting from herpes, pseudomo can be painful. Initial symptoms can include mouth Sore nas, Staph, and hepatitis. ness, fever, Sore throat, or Swollen lymph glands. Small Cold sores, also known as fever blisters, are clusters of children sometimes drool before a cold sore appears. After small blisters on the lip and outer edge of the mouth. They the blisters develop, cold sores usually break open, weep are called cold sores or fever blisters because they often clear fluid, and then crust over and disappear after several occur during a viral illness, Such as a cold. Cold Sores are days to a week. small, painful, fluid-filled blisters on the mouth or nose. The Cold sores follow the usual course of herpes simplex virus skin around the blisters is often red and inflamed. The 25 infections in that the first outbreak is usually more painful blisters can break open, weep a clear fluid, and then Scab and lasts longer than recurrent infections. The first time the over after a few days. Cold Sores usually appear on the lips. skin in or around the mouth comes in contact with the herpes Occasionally, they occur on the nostrils, chin or fingers. simplex virus; the outbreak occurs inside the mouth on the Sometimes, cold Sores can occur inside the mouth, but gums, tongue, and throat. This is called gingivostomatitis. typically on the gums or hard palate or roof of the mouth. 30 Cold sores are caused by a viral infection or a virus known This first infection occurs most often in childhood, and the as herpes simplex type I (HSV-1) that attacks the skin and highest incidence of infection occurs between 6 months and nervous system. Cold Sores are the most common manifes three years of age. Children get pain, fever, Swollen lymph tation of a herpes simplex virus infection. Fever blisters are nodes, and can have difficulty Swallowing. These symptoms caused more often by the herpes simplex virus type 1 35 last for about a week and resolve spontaneously. Children (HSV-1) than herpes simplex virus type 2 (HSV-2). HSV-1 with gingivostomatitis are at risk for dehydration if the pain is different from herpes simplex type II (HSV-2), which is keeps them from drinking fluids. the virus that causes the sexually transmitted disease known Once a person has been exposed to the herpes simplex as genital herpes. Herpes simplex virus type 2 is usually virus, the virus remains in the cells in the body and can responsible for genital herpes. However, either type of the 40 reactivate at any time. Reactivation can be triggered by herpes virus can cause Sores in the facial area or on the trauma to the skin, menstruation, Sun exposure, stress, fever, genitals. and other causes. This reactivation produces the lesions we After the first episode of cold sores or fever blisters, the know as cold sores or fever blisters. Fever blisters are most herpes virus lies dormant in the nerves or skin around the often seen on the border of the lip and consist of three to five original area until something sets the virus off into another 45 vesicles. Over the next three to five days, the vesicles can eruption. Herpes simplex virus can be reactivated in become pustular, ulcerative, and then crust over. Symptoms response to various stimuli including UV radiation from Sun are usually most severe 8 hours after the outbreak. Many exposure, stress, a cold, illness, or dental work. Fever and people have about two outbreaks per year, but some people menstruation can also trigger a recurrence of cold Sores. have greater than six outbreaks per year. Cold Sores or fever blisters are contagious and can be 50 Recurrent infections of cold sores are often preceded by spread by direct contact with infected saliva or droplets in a prodrome, symptoms that appear before the outbreak the breath, or by skin to skin contact. Cold sores can be occurs. Common prodromal symptoms for cold Sores or spread through coughing, Sneezing, direct contact with a fever blisters are pain, tingling, and burning. A herpes cold sore, or touching contaminated fluid-such as from prodrome can last from two hours to two days. The first kissing an infected person and touching the person’s saliva. 55 symptoms that can appear during an outbreak of cold Sores Cold Sores can also be spread from one person to an area of may include tingling, burning, or itching in the area around someone else’s body by touching an active cold Sore or the mouth or nose. This first portion of the outbreak is sharing things that a person who has a cold Sore has used. known as the prodromal stage or period. Within a few hours Shared eating utensils, razors and towels can spread the to days, the area may become reddened and develop Small infection of cold Sores. A parent who has a cold Sore can 60 fluid-filled blisters. Several of these small blisters may even spread the infection to their child.